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A QM/MM investigation of the active-ready (Hox) form of [FeFe]-hydrogenase from D. desulfuricans, in which the electronic properties of all Fe-S clusters (H, F and F') have been simultaneously described using DFT, was carried out with the aim of disclosing a possible interplay between the H-cluster and the accessory iron-sulfur clusters in the initial steps of the catalytic process leading to H2 f

The introduction and the diffusion of digital technology have strongly affected the way archaeologists manage and perceive the information detected during the field investigation process. In the last two decades digital instruments have been used in archaeology at any level, and their constant employment increased the opportunities for researchers and scholars to detect, document, analyse and visu

The enzyme 11 beta-hydroxysteroid dehydrogenase type 2 (11BHSD2) converts cortisol to cortisone in the kidney, thereby protecting the mineralocorticoid receptor from the mineralocorticoid actions of cortisol. The syndrome of Apparent Mineralocorticoid Excess (AME), a rare monogenic form of early onset hypertension with autosomal recessive inheritance, is caused by homozygous or compound heterozygo

To investigate the evidence behind supposed advantages of insulin detemir over existing therapy (NPH insulin), we carried out a systematic review. We analysed the available documentation presented after registration of the drug by the European drug regulatory authority (EMEA) and approached the data presented at the authority's Internet site. Some data from Food and Drug Administraion (FDA) contri

Popular Abstract in Swedish Multikonjugerad Adaptiv Optik för Astronomiska Teleskop 1. Atmosfärisk turbulens Allt sedan man på 1600-talet började bruka optiska instrument inom astronomin, för att understödja det mänskliga ögat då man beskådade stjärnhimlen, har astronomer strävat efter att bygga allt större och bättre teleskop för att kunna se längre ut i rymden och skönja allt ljussvagare objekt.This work analyses several aspects of multi-conjugate adaptive optics (MCAO) for astronomy. The research ranges from fundamental and technical studies for present-day MCAO projects, to feasibility studies of high-order MCAO instruments for the extremely large telescopes (ELTs) of the future. The first part is an introductory exposition on atmospheric turbulence, adaptive optics (AO) and MCAO, esta

Current therapy for haemophilia A is guided by severity of the disease, which in turn is best reflected in patients' endogenous factor VIII activity levels. For patients with severe haemophilia (particularly children), prophylaxis with continuous routine factor replacement has become standard of care in developed countries and is gradually becoming the standard of care in developing countries. The

Our purpose was to study different actors opinion about what reasons there are to homelessness among young abusers in Malmö. When we are talking about young abusers we mean those who are under 25 years old. Our central questions were: Which reasons could different actors see? Were the actor’s view of the reasons the same or were there any difference? How was the cooperation between the different a

Villa homes are designed to be able to tackle many injured leading factors. Today's villa homes are planned and projected by many years of experience in villa construction. No matter how well you planned the project planning and execute it, an injury can occur. Moisture and water damage can occur from a variety of factors, both from the outer- and inner factors. The external factors may be in

In this thesis, the objective was to design a base station for a startup company as a compliment to their main product, a control center device. The thesis resulted in a prototype that worked as intended and it fulfilled all desired criteria; charging ability, mountable on walls and placeable on flat horizontal surfaces. The prototype is divided into two parts: One unit, the station, and one unit

This project explored the usage and effectiveness of a natural water filtration system using xylem from Picea Abies, or Norway Spruce. The project is concentrated on the region of southeast and south Asia where people suffer from water contamination, providing a concept of a water filter with comprehensive protection against waterborne diseases. The study implemented secondary research on product

The wind power industry has long remained passive on broader sustainability issues, grounded in the perception that the industry is inherently linked with environmental sustainability. Within the past 5 years, there has been a dramatic change in the stakeholder and corporate perception of sustainability. Increasing expectations from stakeholders are pressuring wind OEMs to transition and advance c

Skogsbruket utgör en ekonomisk tillgång för enskilda skogsägare. Samtidigt spelar skogen en central roll för bevarandet av den biologiska mångfalden, då den fungerar som livsmiljö för många skyddsvärda arter. Artskyddsförordningen (2007:845) innehåller bestämmelser om fridlysning av vissa djur- och växtarter. Fridlysningsbestämmelserna kan inverka på skogsägarens frihet att bruka skogen genom att Forestry serves as a valuable economic resource for individual forest owners. Simultaneously, forests play a crucial role in preserving biodiversity by providing habitats for protected species. The Swedish Species Protection Ordinance (2007:845) contains provisions aimed at safeguarding these species, which can restrict forest owners' freedom to use their properties through prohibiting logging

This thesis will explore the development and influence of human rights protection in the field of direct taxation. Human rights protection in European Union began with the adoption of the Convention for the protection of human rights and fundamental freedoms, but over time with the adoption of the Charter, it has taken a leading role in the EU taxation area. This most significant change in the EU

ar. Enorma framsteg har gjorts de senaste decennierna i neonatalvården (vård för nyfödda barn) och omkring 80% av EPT-barn i Sverige överlever. Dessa framsteg innefattar bl.a. administrering av kortison för att påskynda lungmognaden, modern teknisk utrustning, bättre kunskaper om neonatala sjukdomar m.m. Globalt är överlevnaden av EPT-barn lägre i länder med sämre ekonomiska förutsättningar och däAim: To evaluate a pipeline for automatic MRI brain segmentation and volumetric tissue structure quantification in a cohort of extremely preterm infants. Methods: 13 extremely preterm neonates underwent MRI-scanning at a term equivalent age. Seven of these subjects had suitable MRI sequences and were analyzed in the pipeline. Segmentation of MRI brain images into brain tissue types and parcellati

Denna uppsats ämnar undersöka, analysera och diskutera försvarlighetsbedömningar vid förtal enligt brottsbalken. Uppsatsen söker svaret på hur bedömningen går till samt hur den bör gå till. Undersökningen är begränsad till att omfatta förtal begångna på sociala medier då någon blivit utpekad som brottsling. Uppsatsen avhandlar även aspekten vad som är relevant vid en försvarlighetsbedömning vid fö

Antalet rapporterade cancerfall i Sverige har mer än dubblerats sedan 1970-talet. Cancerfonden rapporterade att 61100 personer blev diagnostiserade med cancer under 2015 och att prostatacancer är den mest förekommande typen av cancer. Ett vanligt sätt att behandla prostatacancer är extern strålbehandling, där en strålkälla (vanligtvis en linjäraccelerator) som befinner sig utanför kroppen används Purpose/objective The main objective was to create a software that automates the process of creating treatment plans used for Pareto front-based dose planning for prostate cancer patients. A second objective/purpose was to add a robustness test to this program to evaluate the effect of prostate movements on the treatment plans. Material/method An IronPython program was designed to control and col

The aim of this study was to explore how six professionals from three organizations that handle cases of domestic violence, depict partner violence and how they describe and understand the problem of domestic violence in relation to individual and gender perspectives. To analyze this theme, I used qualitative method. Interviews was held with staff members from three different cells: a social servi

Background: Routine oxygen therapy has for a long time been used as part of the standard treatment for myocardial infarction (MI), despite a lack of randomized controlled trials (RCT) to support the use. A recent Cochrane review on oxygen treatment for normoxic MI patients found no evidence supporting the use, rather the trend pointed towards possible harm for oxygen. The SOCCER-study (Supplementa

Uppsatsen behandlar rättsfiguren culpa in contrahendo, vårdslöshet i samband med avtalsförhandlingar. Huvudregeln är att parterna förhandlar på egen risk vilket innebär att de inte kan räkna med att få sina förhandlingskostnader ersatta i det fall avtalsförhandlingarna strandar. Culpa in contrahendo utgör ett undantag till denna huvudregel. För att ersättning enligt culpa in contrahendo ska kunnThis thesis analyzes culpa in contrahendo, negligence in the negotiations of an agreement. The general rule is that the parties negotiate at their own risk and are not compensated for any costs in case that the negotiations fails. Culpa in contrahendo is one exception to that general rule. For culpa in contrahendo to apply there must be a duty of care between the negotiating parties. With duty of