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The greater sensitivity of magnetic resonance spectroscopy (MRS) compared with MRI to brain abnormalities in Rasmussen's encephalitis was demonstrated in a 3-year-old boy. The patient, with symptoms, signs and morphological findings consistent with Rasmussen's encephalitis, was followed with MRI and MRS over 30 months. That metabolic changes can be disclosed by MRS before the development of sympto
Factors influencing the effect of pilot-injection on main-injection combustion were investigated using heat release analysis in a heavy-duty diesel engine fuelled with standard diesel fuel, and included the effect of those factors on engine performance and emissions.Combinations of pilot injection parameters i.e. pilot start of injection, pilot mass, pilot-main injection separation, and rail pressFactors influencing the effect of pilot-injection on main-injection combustion were investigated using heat release analysis in a heavy-duty diesel engine fuelled with standard diesel fuel, and included the effect of those factors on engine performance and emissions.Combinations of pilot injection parameters i.e. pilot start of injection, pilot mass, pilot-main injection separation, and rail press
Enligt 1 kap. 2 § första stycket brottsbalken krävs som huvudregel uppsåt hos den som begår en otillåten gärning, medan oaktsamhet aktualiseras i de fall det är särskilt föreskrivet. Svensk straffrätt utgår från tre uppsåtsformer: avsikts-, insikts- och likgiltighetsuppsåt. Likgiltighetsuppsåt infördes i svensk rätt genom rättsfallet NJA 2004 s. 176 och utgör sedan dess uppsåtets nedre gräns, det As a general rule, Chapter 1, Section 2 of the Swedish Criminal Code requires intent on the part of the offender for a criminal act to be punishable, whereas negligence is relevant only where expressly prescribed. Swedish criminal law recognises three forms of intent: direct intent, indirect intent, and intent by indifference. Intent by indifference was introduced into Swedish law through the Supr
Aims: In a co-twin control design, we aimed to examine whether individuals who initiate metformin treatment have an altered risk of incident diagnosis of osteoarthritis (OA), for up to 11 years after starting the treatment, compared with their non-treated co-twin. Methods: In all twin pairs different for metformin treatment (N=1 261 pairs) and all eligible twins/singletons (N=52 341) aged 35–75 ye
Epigenome-wide studies of pancreatic islets provide valuable insights into type 2 diabetes (T2D) but lack methylomes from individual cell types. Here we show changes to alpha and beta cell-specific methylomes and transcriptomes from people with or without T2D, using whole-genome bisulfite sequencing and RNA sequencing. We discover 22,544 differentially methylated regions annotated to 7,975 genes i
The prevalence of anthropogenic climate disasters is increasing, and this phenomenon is partly attributable to the substantial emissions of various industries. Renewable hydrogen (H2) possesses properties that are well suited to the decarbonization of hard-to-abate industries. This energy source has seen a surge in interest and necessity in recent years, driven by regulatory targets set by the Eur
STUDY QUESTIONDoes endometriosis and/or adenomyosis, diagnosed using the International Deep Endometriosis Analysis (IDEA) group and the Morphological Uterus Sonographic Assessment (MUSA) group revised definitions, impact cumulative live birth rates (CLBR) after three consecutive IVF or ICSI treatments?SUMMARY ANSWERWomen with endometriosis and/or adenomyosis, as diagnosed using transvaginal ultras
Deficiency in C1 inhibitor (C1INH, SERPING1) is canonically associated with hereditary angioedema (HAE-C1INH) but not thrombosis. To determine the thrombosis risk conferred by loss of C1INH in the general population, we studied genetically-defined C1INH deficiency across 635,823 participants. Functionally deleterious germline coding variation in SERPING1 was rare (~1:10,000), indicating strong gen
Ethiopia achieved a remarkable episode of agricultural intensification from the mid-1990s to the late-2010s, yet the political mechanisms that enabled this transformation—and the distributional and environmental consequences that followed—remain insufficiently understood. This article ex- amines how political leadership, understood in institutional rather than personalistic terms, shaped both the Ethiopia achieved a remarkable episode of agricultural intensification from the mid-1990s to the late-2010s, yet the political mechanisms that enabled this transformation—and the distributional and environmental consequences that followed—remain insufficiently understood. This article ex- amines how political leadership, understood in institutional rather than personalistic terms, shaped both the
This chapter builds upon three streams of experience by its author: (a) one related to his six-year term as the first UN Special Rapporteur on human rights and counterterrorism (2005-2011), namely the identification of the absence of a proper international definition of terrorism as an important source of human rights abuses, (b) his observation of actual court practice and media coverage where de
– 304 – Utbildningsplan 1 Identifikation • Programmets namn och inriktning: musikerutbildning, sång. • Omfattning i högskolepoäng: 120. • Nivå: A. • Programkod: KAMUS. Inriktning: SÅNG. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 14 februari 2007. Utbild ningsplanen träder i kraft den 1 juli 2007. 2 Programbeskrivning Musikerutbildning, piano, syftar till att utbilda mus
https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildn_kurspl_master_sang13.pdf - 2026-05-22
Background: Renalase (gene name RNLS), a recently discovered enzyme with monoamine oxidase activity, is implicated in the degradation of catecholamines. Recent studies delineate a possible role of this enzyme in blood pressure (BP) maintenance and cardiac protection and two single nucleotide polymorphisms, RNLS rs2576178 A > G and rs2296545 C > G have been associated with hypertension. The latter
BACKGROUND: Cost-effective fermentation of lignocellulosic hydrolysate to ethanol by Saccharomyces cerevisiae requires efficient mixed sugar utilization. Notably, the rate and yield of xylose and arabinose co-fermentation to ethanol must be enhanced. RESULTS: Evolutionary engineering was used to improve the simultaneous conversion of xylose and arabinose to ethanol in a recombinant industrial Sacc
We study agents situated in partially observable environments, who do not have sufficient resources to create conformant (complete) plans. Instead, they create plans which are conditional and partial, execute or simulate them, and learn from experience to evaluate their quality. Our agents employ an incomplete symbolic deduction system based on Active Logic and Situation Calculus for reasoning abo
Popular Abstract in Swedish Nya operationsmetoder för trokantära höftfrakturer – klinisk och biomekanisk utvärdering av Medoff´s glidplatta och Twin hook Akademisk avhandling av Ola Olsson Sammanfattning på svenska Benskörhet är en folksjukdom som bidrar till uppkomst av en rad typfrakturer. Till dessa hör höftfrakturer, som utgör ett folkhälsoproblem och en stor utmaning för samhällets sjuvårdsIn allowing compression along the femoral shaft (uniaxial dynamization) and optional compression along the femoral neck (biaxial dynamization), the Medoff sliding plate (MSP) represents a new principle in the fixation of trochanteric hip fractures. The Twin hook with 2 apical hooks was designed as an alternative to the lag screw. In 3 prospective consecutive case series and 1 prospective randomize
To investigate the evidence behind supposed advantages of insulin detemir over existing therapy (NPH insulin), we carried out a systematic review. We analysed the available documentation presented after registration of the drug by the European drug regulatory authority (EMEA) and approached the data presented at the authority's Internet site. Some data from Food and Drug Administraion (FDA) contri
A QM/MM investigation of the active-ready (Hox) form of [FeFe]-hydrogenase from D. desulfuricans, in which the electronic properties of all Fe-S clusters (H, F and F') have been simultaneously described using DFT, was carried out with the aim of disclosing a possible interplay between the H-cluster and the accessory iron-sulfur clusters in the initial steps of the catalytic process leading to H2 f
The introduction and the diffusion of digital technology have strongly affected the way archaeologists manage and perceive the information detected during the field investigation process. In the last two decades digital instruments have been used in archaeology at any level, and their constant employment increased the opportunities for researchers and scholars to detect, document, analyse and visu
Transient experiments are one of many techniques available to study heterogeneous catalysis and the catalysts used. The results obtained by transient experiments contain valuable information that is helpful in explaining reaction mechanism and interaction at the catalytic surface. The work that was performed covers areas that reach from the selective (ammoxidation) and complete oxidation of propan
Popular Abstract in English Proteins are molecular machines of the human body which regulate all life sustaining processes such as energy production, communication, transport of essential molecules, defense against microbes, etc. They are built by small molecular units called amino acids, bound together like pearls on a necklace. Each amino acid consists of a common part and a unique side chain. TAnisotropic protein interactions have a strong orientation dependence resulting from an uneven distribution of charged and hydrophobic residues on the protein surface. They play an important role in protein behaviors such as protein association, surface adsorption and phase separation. In this thesis, we have studied the effect of anisotropic interactions on the behavior of various proteins mainly
