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The aim of the project has been to elucidate molecular events leading to amyloidosis in Hereditary Cystatin C Amyloid Angiopathy (HCCAA) patients, to enable simple diagnosis of the disease and with the ultimate goal to understand the amyloid formation process in detail, in order to develop inhibitors to the process. At the DNA level, a point mutation segregating with HCCAA was identified in the cy
Twenty-nine consecutive cases with a t(8;21)(q22;q22) in the bone marrow (BM) karyotype were retrospectively studied concerning clinical, morphological and cytogenetic data. All had been diagnosed as acute myeloid leukaemia (AML), 27 FAB subtype M2 and two M1, comprising 5% of all cytogenetically analysed AML during 18 yr. Auer rods were the most consistent t(8;21)-associated morphological finding
This thesis presents investigations for the improvement of electrical contact and catalytical properties of two fungal redox enzymes, cellobiose dehydrogenase (CDH) and pyranose dehydrogenase (PDH), with electrodes and the use of the prepared electrodes as carbohydrate biosensors and in enzymatic biofuel cells. The performance of enzyme modified electrodes can be improved in two ways, by modifying
Popular Abstract in Swedish Populärvetenskaplig sammanfattning: När udda blir mainstream - om stress och likriktning i växtsamhället I skogen råder stress på många sätt, och precis som i det mänskliga samhället har stressen i växtsamhället ökat under de senaste decennierna. Dessa händelser har heller inte skett oberoende av varandra. Vårt allt snabbare tempo med krav på ökad tillväxt har inte baSoil acidification has become a source of serious concern in many parts of the world. In southern Sweden, the deposition of acidifying substances, such as nitrogen and sulphur compounds, has decreased the mean pH of forest soils by almost one unit since the 1950s. Apart from H+ ions themselves being harmful to plant roots, the potential toxicity of aluminium (Al) is increased when pH drops below 5
Idiopathic Scoliosis is a spinal deformity affecting approximately 3% of otherwise healthy children or adolescents. The etiology is still largely unknown but has an important genetic component. Genome-wide association studies (GWAS) have identified a number of common genetic variants that are significantly associated with idiopathic scoliosis in Asian and Caucasian populations, rs11190870 close to
Context. On the order of 20% of the very metal-poor stars in the Galaxy exhibit large carbon enhancements. It is important to establish which astrophysical sites and processes are responsible for the elemental abundance patterns of this early Galactic population. Aims. We seek to understand the nature of the progenitors of three main-sequence turnoff Carbon-Enhanced Metal-Poor (CEMP) stars, CS 310
Huntington's disease is an autosomal dominant disease which presents with striatal and cortical degeneration causing involuntary movements, dementia and emotional changes. We employed 16-week-old transgenic Huntington mice (R6/1 line developed by Bates and coworkers) that express exon 1 of the mutant human Huntington gene with 115 CAG triplet repeats. At this age, R6/1 mice do not exhibit an overt
Objective To standardize the evaluation of regional fetal brain blood perfusion, using power Doppler ultrasound (PDU) to estimate the fractional moving blood volume (FMBV) and to evaluate the reproducibility of this estimation. Methods Brain blood perfusion was evaluated in 35 normally grown fetuses at 28-30 weeks of gestation, using PDU. The following cerebral regions were included in the PDU col
Air flow rate through filters and face masks is one important determinant of the final protection factor of a respiratory protective device in use. Respiratory minute volumes and instantaneous breath flow rates were measured in eight subjects during treadmill work using three types of filtering respirators and one control breathing mask. Work comprised five consecutive bouts of walking at 5 km/h w
Concerns regarding environmental issues have led to increasing efforts for investigating sustainable production routes for the future industry that is based on renewable resources. Among the biobased chemicals, the C3-chemicals 3-hydroxypropionaldehyde (3-HPA), 1,3-propanediol (1,3-PDO) and 3-hydroxypropionic acid (3-HP), have been identified as top candidates for the chemical industry. Lactobacil
PURPOSE: There is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.METHOD: Semi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky’s theory of sense of coherence. The SRQR checklist was used. RESULTS: Patient’sPurposeThere is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.MethodSemi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky's theory of sense of coherence. The SRQR checklist was used.ResultsPatient's coping
Purpose: To compare management and outcomes for critically ill women and men with sepsis in the emergency medical services (EMS), the emergency department (ED) and the ICU. Methods: We used two prospectively compiled Swedish national quality registers, the National Quality Sepsis Registry and the Swedish Intensive Care Registry to identify a nationwide cohort of 2720 adults admitted to an ICU with
Pollination is a key ecosystem service for global agriculture but evidence of pollinator population declines is growing. Reliable spatial modelling of pollinator abundance is essential if we are to identify areas at risk of pollination service deficit and effectively target resources to support pollinator populations. Many models exist which predict pollinator abundance but few have been calibrate
In Sweden and elsewhere in the world the construction industry has encountered criticism due to its lower productivity gains in comparison to other industries. This is why continual improvement of processes and forms of cooperation are important, as is utilisation of technologies giving greater efficiencies. The focus in Sweden has mainly been on the construction of multifamily buildings, both bec
This paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis indThis paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis ind
Introduction: We investigate the risks of subsequent primary bone cancers after childhood and adolescent cancer in 12 European countries. For the first time, we satisfactorily address the risks beyond 40 years from diagnosis and beyond 40 years of age among all survivors.Methods: This largest-ever assembled cohort comprises 69 460 five-year survivors of cancer diagnosed before age 20 years. Standa
Samhället idag kännetecknas av digital interaktion, där både privata såväl som yrkesmässiga kontakter sker via olika tekniska plattformar. Människor skrol-lar, kommunicerar och tar till sig information via mobiltelefoner eller datorer vilket har blivit det normala sättet att interagera i vardagen. Allt fler rättsområ-den har tagit digitaliseringen i beaktning, men det finns fortfarande rättsområ-dSociety today is characterized by digital interaction, with both private and pro-fessional contacts taking place through various technological platforms. Peo-ple browse, communicate and absorb information via mobile phones or com-puters, which has become the normal way of interacting in everyday life. More and more areas of law have taken digitalization into account, but there are still areas of l
Lupin-guide: Approving Orders and Invoices in Lupin Proceedo Support: https://www.staff.lu.se Approving Orders and Invoices in Lupin Proceedo Contents What does approving orders and invoices entail? ...................................................... 1 Approving orders ........................................................................................................ 1 Approving invoices .
https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2025-04/guide-lupin-proceedo-approval.pdf - 2026-06-01
Namnl.st-1 1Indirect Discrimination and the European Court of Justice Indirect Discrimination and the European Court of Justice A comparative analysis of European Court of Justice case-law relating to discrimination on the grounds of, respectively, sex and nationality Alexandra Wengdahl AlexandraWengdahl@hotmail.com 3Indirect Discrimination and the European Court of Justice2 CFE Working paper seri
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp15.pdf - 2026-06-01
SMAA40 Risk and Crisis Management Lund University Faculty of Social Sciences SMAA40, Risk and Crisis Management, 7.5 credits Risk- och krisledning, 7,5 högskolepoäng First Cycle / Grundnivå Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 2021-12-15 to be valid from 2022-08-29, autumn semester 2022. General Information The co
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2022-12/Kp_SMAA40_HT23.pdf - 2026-06-01
