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Characterization of DAT missense mutations in novel mouse models

The dopamine transporter (DAT) is responsible for dopamine (DA) clearance in the synaptic cleft, and thus crucial for maintaining DA homeostasis in the central nervous system (CNS). Mutations in the DAT coding gene have been associated with both movement and psychiatric disorders, such as parkinsonism and attention-deficit hyperactivity disorder (ADHD). However, the detailed contribution of DAT in

Nazisters demonstrationsfrihet – eller häcklarens veto? - En komparativ studie mellan Sverige och USA

I september 2017 fick nazistiska Nordiska Motståndsrörelsen demonstrationstillstånd i Göteborg, vilket orsakade en stor debatt i Sverige. En liknande debatt väcktes i USA 1977 när en nazistisk grupp ansökte om att demonstrera. Händelserna väcker frågor; bör demonstrationsfriheten innefatta nazistiska demonstrationer? Vad är statens förhållningssätt till våldsamma motdemonstranter? Syftet med uppsaIn September 2017, the Nordic Resistance Movement received a permit to march through Gothenburg, which ignited a big debate in Sweden. A similar debate was had in 1977 in the United States (U.S.), when a neo-Nazi group applied for a permit to demonstrate. These events provoke questions; should the right to demonstrate include neo-Nazi groups? What should the state’s approach be to violent counter-

Antikorruptionsförebyggande tredjepartsbesiktning och GDPR

Tredjepartsbesiktning innebär att blivande eller befintliga affärspartners undersöks i syfte att säkerställa att verksamhetsutövarens verksamhetsled utgör en låg risk för korruption, vilket i vissa länder krävs genom lag. Faktorer som i regel anses som varningsflaggor i riskbedömningen inför en affärstransaktion är till exempel om en affärspartner har dömts för något brott av korruptiv karaktär elThird party due diligence is an investigation of prospective or existing business partners in order to ensure a low risk of corruption. In certain countries such an investigation is required by law. Factors to consider in the risk assessment are for example whether a potential or existing business partner has been convicted of any corruption related crime or is associated with political circles. S

Utrymning genom inåtgående dörrar - Påverkan av personer med nedsatt rörelseförmåga

Denna studie undersöker utrymning genom inåtgående dörrar, något som bör undvikas enligt svenska byggregler när antalet personer i en lokal överstiger 30. Trots detta är de specifika utmaningarna och påverkande faktorerna, särskilt vad gäller personer med nedsatt rörelseförmåga, till stor del outforskade. För att belysa detta genomfördes en litteraturstudie samt utrymningsförsök med 36 deltagare (

Accelerometer-Measured Physical Activity and Sedentary Behavior in Individuals With and Without Chronic Diseases : Cross-Sectional Results of 27,890 Adults From the Swedish CArdioPulmonary BioImage Study Cohort

Background: This study compared levels of physical activity (PA) and sedentary behavior (SB) in adults with and without chronic diseases or multimorbidity, acknowledging sociodemographic factors. Methods: A cross-sectional analysis was conducted with data from 27,890 participants (52% women), aged 50–64, from the Swedish CArdioPulmonary bioImage Study cohort. Over 1500 chronic diseases were includ

A Whisker of Truth: A Multimodal Interdisciplinary Machine Learning Approach to Vocal, Visual, and Tactile Signals in the Domestic Cat

We propose a multimodal deep learning framework for automated analysis ofcat–human communication, integrating acoustic, visual, and tactile signals throughtransformer-based fusion. Using the largest expert-annotated dataset of its kindand interdisciplinary collaboration, we combine semi-supervised learning withethological and phonetic expertise to detect subtle behavioural and phonetic cues,enable

Antagningsprocess

Är jag behörig att söka till forskarutbildningen vid Medicinska fakulteten och hur går antagningsprocessen till? Här kan du läsa mer om antagningen. Vägen från det att du börjat fundera på doktorandstudier och vad som sedan behövs för att du ska kunna ansöka och börja studera.Antagning till utbildning på forskarnivå vid Medicinska fakulteten sker löpande under året och den sker i ett antal steg. F

https://www.medicin.lu.se/forskning/utbilda-dig-pa-forskarniva/antagningsprocess - 2026-05-28

Observed binary populations reflect the Galactic history. Explaining the orbital period-mass ratio relation in wide hot subdwarf binaries.

Context. Wide hot subdwarf B (sdB) binaries with main-sequence companions are outcomes of stable mass transfer from evolved red giants. The orbits of these binaries show a strong correlation between their orbital periods and mass ratios. The origins of this correlation have, so far, been lacking a conclusive explanation. Aims. We aim to find a binary evolution model which can explain the observed

Manual For Advertising - TendSign Plus (PDF, 1938 KB, Ny Flik) V230510

Användarmanual Visma TendSign Plus VISMA COMMERCE AB +46 13 47 47 500 • tendsignsupport@visma.com • www.tendsign.com Uppdaterad 2014-05-21 Innehållsförteckning Visma TendSign Plus 1. Navigering ........................................................................................................................................... 2 1.1 Min startsida ..............................................

https://www.staff.lu.se/sites/staff.lu.se/files/2023-05/Manual%20for%20advertising%20-%20TendSign%20Plus%20(PDF,%201938%20kB,%20ny%20flik)%20v230510.pdf - 2026-05-28

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Abstract in Danish Denne artikel rejser spørgsmålet om grunderne til neuropsykiatriens dominans inden for feltet mentala forstyrrelser. I kapitlets første del søges orsagerne i neuropsykiatriens videnskablige inhold. Diskussionen vil især dreje sig om neuropsykiatrins klassifikations- og førklaringssystem. Det vil bland andet framgå, at neuropsykiatriens fenomenologisk baserede klassifikationer (D

Patient advocacy: barriers and facilitators

BACKGROUND: During the two recent decades, advocacy has been a topic of much debate in the nursing profession. Although advocacy has embraced a crucial role for nurses, its extent is often limited in practice. While a variety of studies have been generated all over the world, barriers and facilitators in the patient advocacy have not been completely identified. This article presents the findings o

Nonyrast States in the Odd-odd N = Z Nucleus 62Ga

Low-lying excited states in the odd-odd N = Z nucleus 62Ga have been investigated following the heavy-ion fusion-evaporation reaction 40Ca(24Mg,pn)62Ga near the Coulomb barrier. Special emphasis is devoted to the search for nonyrast states. The extended decay scheme of 62Ga is compared to spherical shell-model calculations employing the pf5/2g9/2 valence space.

Global catchment modelling usingWorld-Wide HYPE (WWH), open data, and stepwise parameter estimation

Recent advancements in catchment hydrology (such as understanding catchment similarity, accessing new data sources, and refining methods for parameter constraints) make it possible to apply catchment models for ungauged basins over large domains. Here we present a cutting-edge case study applying catchment-modelling techniques with evaluation against river flow at the global scale for the first ti

Avocado production and local trade in the southern highlands of Tanzania : A case of an emerging trade commodity from horticulture

Avocado crop in Tanzania is sparingly investigated regardless of being an important fruit commodity. This study was undertaken to explore the yield and the value chain of this crop in the country. Data were collected mainly by face-to-face interviews with 275 avocado farmers, 231 avocado traders and 16 key informants. Descriptive statistics, Chi-square test and one-way analysis of variance were us

Law and Digital Society

In this article we argue the need for more socio-legal scrutiny in a digitally mediated and data-driven development. We focus and briefly outline socio-legally relevant aspects of the “sharing” economy, that poses a number of conceptual issues on how we understand and regulate innovative platform based ventures. This also arguably underscores a number of issues relating to the role of consumer and

Analysis of Deformation of Gas Diffusion Layers and the Impact on Performance of PEM Fuel Cells

Proton exchange membrane (PEM) fuel cells have been promoted due to significant breakthroughs in various aspects and increasing public interests. The porous features of the gas diffusion layer (GDL) and the necessary assembly processes generate localized pressure forces on the channel/shoulder structure of the bi-polar plates (BPP). As a consequence, the assembly pressure acting on a single cell a

Template-Based Design Analysis – An Alternative Approach for the Engineering Designer to Perform Computer-Based Design Analysis

Popular Abstract in Swedish Vid framtagning av nya produkter måste man utgå ifrån de behov som den blivande kunden ställer i form av krav och önskemål på produkten för att den ska vara intressant att inhandla och använda. För att säkerställa att den blivande produkten har de egenskaper som efterfrågas, används idag omfattande simuleringar av den blivande produktens egenskaper. Simuleringar består The current trend in industry to encourage engineering designers to take an active part in the analysis of their own design solutions is apparent in many companies today, domestically as well as abroad. From a research project with the objective to develop a computer-based design system for the design of lightweight grippers, one of the major difficulties was to overcome the system users’ lack of

Selected contribution: role of spleen emptying in prolonging apneas in humans

This study addressed the interaction between short-term adaptation to apneas with face immersion and erythrocyte release from the spleen. Twenty healthy volunteers, including ten splenectomized subjects, participated. After prone rest, they performed five maximal-duration apneas with face immersion in 10 degrees C water, with 2-min intervals. Cardiorespiratory parameters and venous blood samples w