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This is an inquiry into how aspects of the present human reality came to being and thereby also an investigation into limitations and potentialities of this “present”. An important argument in this essay is that there exists a mutually affective relationship between culture and politics and that this relationship implies both possibilities and constraints. With this in mind I try to critically inv

Crowdsourcing is a relatively new technique which aims to make a specific group of people contribute solutions to simple tasks or problems that are published online by some organization. For this they get some reward, which is usually economic in nature. This technique can be embraced by any kind of company, and since it is done online, it can turn out to be a bit problematic, especially when it c

Den här uppsatsen har som syfte att undersöka förvaltarskapets anordnande och belysa verkningarna av ett sådant anordnande. I uppsatsen utreds vilka grunderna för anordnande av förvaltarskap är och hur dessa tolkas enligt gällande rätt. Vidare analyseras hur den praktiska tillämpningen av föräldrabalkens relevanta bestämmelser ser ut samt huruvida tillämpningen är ändamålsenlig i förhållande till The purpose of this essay is to examine the arrangement of adult guardian-ship for people with impaired decision-making capacity, and to illustrate the effects of such an arrangement. The essay presents the conditions for the arrangement of adult guardianship and how the conditions are interpreted. It further analyzes the application in Swedish courts of the relevant provisions and whether the app

Purpose: The purpose of the thesis is to investigate how organizations should be designed in order to work in the best possible way in China. Method: A theoretical background has been studied. The background covered mainly cultural studies, where a comparison between Sweden and China was made, and also design parameters for an organization. An empirical study took place in Shanghai, China, where m

lnvestigation of weak gravel for road construction has been going on at VTI for many years. The overall aim has been to find test methods that correspond with what happens in the road and that are easy to use in any road laboratory. Following methods have been used in this investigation: planetarytype mixer for wear tests, freeze-thaw variation for weathering tests, Californian Bearing Ratio (CBR)

In this article, we review recent theoretical work that has complemented the extensive experimental data available for multicopper oxidases (MCO) and led to the elucidation of the reaction mechanism of this class of enzymes. The MCOs couple four one-electron oxidations of substrates at the mononuclear type 1 copper (Cu-T1) site with the four-electron reduction of dioxygen at the trinuclear copper

Artificial neural network (ANN) ensembles have long suffered from a lack of interpretability. This has severely limited the practical usability of ANNs in settings where an erroneous decision can be disastrous. Several attempts have been made to alleviate this problem. Many of them are based on decomposing the decision boundary of the ANN into a set of rules. We explore and compare a set of new me

Rational drug design is predicated on knowledge of the three-dimensional structure of the protein-ligand complex and the thermodynamics of ligand binding. Despite the fundamental importance of both enthalpy and entropy in driving ligand binding, the role of conformational entropy is rarely addressed in drug design. In this work, we have probed the conformational entropy and its relative contributi

High poly(3-hydroxybutyrate) (PHB) content and volumetric productivity were achieved by fed-batch culture of Halomonas boliviensis using a defined medium. Initial shake flask cultivations in a minimal medium revealed that the growth of H. boliviensis was supported only when the medium was supplemented with aspartic acid, glycine, or glutamine. Addition of 0.1% (w/v) glutamine in the medium resulte

Romania has for a long time been lacking good palaeoenvironmental records, particularly for the Late Quaternary. A chronological framework had been nearly absent and the vegetation development had been reconstructed entirely from pollen data. Data sets from this part of Europe are important for assessing the spatial variability of past vegetation and climatic changes and to reconstruct tree migrat

An important issue in clinical neural grafting is whether a second instriatial allograft can survive well in a patient who has received an allograft before. In this study, the survival, immunogenicity and function of intrastriatal grafts of allogeneic or syngeneic embryonic dopamine-rich tissue in rats which had previously received either an intrastriatal allo- or syn-graft or sham injections were

Older people with arrhythmias comprise a large group requiring complex care, posing many healthcare challenges. Rapid growth of the older population demands a better understanding of the needs of this patient group. The aim of this thesis was to investigate arrhythmia prevalence, incidence, survival, and experiences from the perspective of a geriatric population (aged 60+ years), and to examine th

New optically stimulated luminescence (OSL) ages show that sandy deposits overlain by Late Weichselian subglacial till in central Latvia are of Early to Middle Weichselian age. The finer chronological resolution of unconsolidated sediment deposition in the Central Latvian Lowland (CLL) remains relatively unstudied, and here we provide a first characterisation of the deposits with respect to their

In recent years a growing amount of research has been conducted in the area of workplace incivility. Whereas many studies have focused on the victims and the consequences of incivility, little attention has been paid to the perpetrators and antecedents of workplace incivility. This study aims to identify possible antecedents of workplace incivility, by investigating organizational aspects as well In recent years a growing amount of research has been conductedin the area of workplace incivility. Whereas many studies havefocused on the victims and the consequences of incivility, littleattention has been paid to the perpetrators and antecedents ofworkplace incivility. This study aims to identify possibleantecedents of workplace incivility, by investigating organizationalaspects as well as the

TGF-β can act as a tumor suppressor at early stages of cancer progression and as a tumor promoter at later stages. The E3 ubiquitin ligase Arkadia (RNF111) is a critical component of the TGF-β signaling pathway, being required for a subset of responses, those mediated by Smad3-Smad4 complexes. It acts by mediating ligand-induced degradation of Ski and SnoN (SKIL), which are 2 potent transcriptiona

Ligand exchange on square-planar Pt(1,4-dithiane)2(2+), Pd(1,4-dithiane)2(2+), and Pt(Me2S)4(2+) has been studied as a function of temperature and pressure by H-1 NMR line-broadening, isotopic labeling, and magnetization transfer experiments with deuteriated nitromethane as solvent. Second-order rate constants and activation parameters are as follows: for 1,4-dithiane exchange on Pt(1,4-dithiane)2Ligand exchange on square-planar Pt(1,4-dithiane)2(2+), Pd(1,4-dithiane)2(2+), and Pt(Me2S)4(2+) has been studied as a function of temperature and pressure by H-1 NMR line-broadening, isotopic labeling, and magnetization transfer experiments with deuteriated nitromethane as solvent. Second-order rate constants and activation parameters are as follows: for 1,4-dithiane exchange on Pt(1,4-dithiane)2

Immediate and long-term microvascular effects of chondroitinase ABC, 200 unit/ml, were analyzed in ten hamsters. The immediate effects on the microcirculation were studied by vital microscopy following local injection in the cheek pouch. There were no detectable effects on the microvascular blood flow during the 60 minutes of observation for chondroitinase ABC or the control. A therapeutic concent

Akademi och bransch har över decennier identifierat faktorer som påverkar folks val av färdsätt. Faktorerna har i förlängningen föranlett en lång rad av åtgärder som visat sig kunna öka kollektivtrafikens marknadsandel, vilket är avgörande för ett mer hållbart transportsystem. Dock innebär såväl skiljande omständigheter som sammanfallande åtgärdsimplementeringar en kunskapslucka kring vilka effektFactors determining the modal choice of travellers have been identified in plenty by both academia and the transport sector. In turn, these have provided an array of measures and strategies proven effective in increasing ridership—necessary to ensure a sustainable transport system. With differing circumstances and often coinciding implementations, little is, however, known about what effect can be

With mobile phones often being used to type sensitive information, it is important that they remain secure and leak no information. One conceivable channel for information leakage, though, is the motion sensors accelerometer and gyroscope, sensors that require no permission to be used by an app. Do the data they produce contain information about the keys being typed? To answer this question, thi