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Although protein coding genes occupy only a small fraction of genomes in higher species, they are not randomly distributed within or between chromosomes. Clustering of genes with related function(s) and/or characteristics has been evident at several different levels. To study how common the clustering of functionally related genes is and what kind of functions the end products of these genes are i
Dodecin from Halobacterium salinarum is a dodecameric, hollow-spherical protein, which unspecifically adopts flavin molecules. Reduction of flavin dodecin holocomplexes induces dissociation into apododecin and free flavin. Unspecific binding and dissociation upon reduction were used as key properties to construct an electrochemically switchable surface, which was able to bind and release dodecin a
The soot particle size distribution was studied via numerical simulation under diesel like engine conditions using a detailed kinetic soot model. Two different mathematical methods of the soot model description have been used in this work. In the first part of the work, the method of moments is presented. In addition, a so called sectional method for the soot particle size distribution function in
The intangible nature of software means that traditional processes for managing product development are not sufficiently effective. This, in combination with the increasing share of software in technical products, has had the effect of making it difficult to identify improvement proposals for engineering processes in many cases. This thesis uses both qualitative and quantitative research methods t
Romania has for a long time been lacking good palaeoenvironmental records, particularly for the Late Quaternary. A chronological framework had been nearly absent and the vegetation development had been reconstructed entirely from pollen data. Data sets from this part of Europe are important for assessing the spatial variability of past vegetation and climatic changes and to reconstruct tree migrat
The projection of primary afferents onto spinal interneurons constitutes the first step in sensorimotor transformations performed by spinal reflex systems. Despite extensive studies on spinal somatotopy, uncertainties remain concerning the extent and significance of representational overlap and relation to spinal reflex circuits. To address these issues, the cutaneous projection from the hindpaw a
Popular Abstract in Swedish Ett stort antal fåglar flyttar vår och höst mellan sina häckningsplatser hos oss i norr till “övervintringsområden”. Många flyttar över stora avstånd, till södra Europa eller till Afrika. Ofta är flyttfåglarnas mål väl definierat, det händer att en fågel häckar på exakt samma plats år efter år. Det finns observationer från t.ex. Afrika att fåglar kan vara lika trogna siBirds are generally capable of accurate orientation. In this thesis I present studies about the external cues and the ecological factors that influences bird orientation. A multitude of environmental cues are used to select and maintain a proper direction. These are visual cues, like the sun and the starry night sky, but other cues like the geomagnetic field, wind and odours also play important ro
Popular Abstract in English Fruits are a key complement to the diet of many people in the southern region of Africa, especially in rural areas. maphilwa (Vangueria infausta L.), maçanica (Ziziphus mauritiana), maçala (Strychnos spinosa), mapsincha (Salacia kraussi), cajú (Anacardium accidentale L.), mavungwa (Landolpia kirki) are some of the most commonly found fruits in sub-Saharan Africa, particThis study concerns the identification and characterisation of volatile components of fruits, and evaluation of the effect of heat treatment and drying on retention or loss of volatiles of fruits. The investigation included developing a procedure to extract volatile components from the fruit matrix, a purification step, separation, identification and quantification. Initial experiments with Vangue
The care of demented patients requires clear communication during care procedures. Earlier studies have shown that nurses were often vague in their verbal communication and unpublished observations indicated that in some cases demented patients continued to be verbally active after the nurses had left. This study aimed at exploring further the initiating and terminating phases of verbal interactio
The search for new treatments for seizures, epilepsies, and their comorbidities faces considerable challenges. This is due in part to gaps in our understanding of the etiology and pathophysiology of most forms of epilepsy. An additional challenge is the difficulty in predicting the efficacy, tolerability, and impact of potential new treatments on epilepsies and comorbidities in humans, using the a
Introduction: Complement activation is involved in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and atypical hemolytic uremic syndrome (aHUS). Autoantibodies to complement inhibitor factor H (FH), particularly in association with deletions of the gene coding for FH-related protein 1 (CFHR1), are associated with aHUS. Methods: Autoantibodies against FH, factor I (FI) and C4b-bindin
Popular Abstract in Swedish Denne afhandling vedrører geriatriske patienters ernæringsproblemer indenfor rammen af geriatrisk rehabilitering. Geriatriske patienter er svækkede ældre mennesker, der er præget af aldring og kronisk sygdom. Den hændelse som er årsag til indlæggelse er ofte som toppen af et isbjerg, hvor der kan ligge mange andre problemer gemt under vandoverfladen. En lungebetændelse The aim was to evaluate the effectiveness and feasibility of functional and nutritional assessments in geriatric rehabilitation in Copenhagen, Denmark, and in addition to study clinically identifiable risk factors for undernutrition, association between nutritional and ADL status, feasibility and effectiveness of nutritional intervention conducted by the nursing staff, and the nursing staffs attit
Planning your exchange studiesOnce you have been nominated to go on an exchange by your home university, you will receive a link to Lund University’s online application for nominated exchange students. This is usually sent out shortly before the application period opens. Please note that you do not apply for exchange studies via University Admissions in Sweden.The academic yearThe academic year co
https://www.lunduniversity.lu.se/study/exchange-and-study-abroad/exchange-studies/exchange-application-and-acceptance - 2026-07-13
All learning outcomes must be fulfilled for the doctoral degree to be granted. Knowledge and understanding For the Degree of Doctor the third cycle student shall demonstrate broad knowledge and systematic understanding of the research field as well as advanced and up-to-date specialised knowledge in a limited area of this field,and demonstrate familiarity with research methodology in general and t
https://www.intramed.lu.se/en/phd-studies/admission-examination/doctoral-degree/public-defence/degree-requirement - 2026-07-13
Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as SCORAD. The management of AD must consider the clinical and pathogenic variabilities of the disease
Many primary care professionals manage injection or infusion therapies in patients with diabetes. Few published guidelines have been available to help such professionals and their patients manage these therapies. Herein, we present new, practical, and comprehensive recommendations for diabetes injections and infusions. These recommendations were informed by a large international survey of current
It is becoming increasingly clear that many proteins start to fold cotranslationally before the entire polypeptide chain has been synthesized on the ribosome. One class of proteins that a priori would seem particularly prone to cotranslational folding is repeat proteins, that is, proteins that are built from an array of nearly identical sequence repeats. However, while the folding of repeat protei
