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Alzheimer's pathology targets distinct memory networks in the ageing brain

Alzheimer's disease researchers have been intrigued by the selective regional vulnerability of the brain to amyloid-β plaques and tau neurofibrillary tangles. Post-mortem studies indicate that in ageing and Alzheimer's disease tau tangles deposit early in the transentorhinal cortex, a region located in the anterior-temporal lobe that is critical for object memory. In contrast, amyloid-β pathology

Zircon geochronology of migmatite gneisses along the Mylonite Zone (S Sweden): a major Sveconorwegian terrane boundary in the Baltic Shield

The southern section of the Mylonite Zone (MZ) is a major lithotectonic terrane boundary in the SW Baltic Shield. It separates the parautochthonous Eastern Segment of the Sveconorwegian orogen from the allochthonous Western Segment. Complex zircons in migmatised and banded orthogneisses along the southern MZ were investigated by ion microprobe analyses guided by backscattered electron imaging to d

Randomized Trial of Sacroiliac Joint Arthrodesis Compared with Conservative Management for Chronic Low Back Pain Attributed to the Sacroiliac Joint

BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro

Risk of complications in patients with conservatively managed ovarian tumours (IOTA5) : a 2-year interim analysis of a multicentre, prospective, cohort study

Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the

Molecular and Structural Biomarkers of Inflammation at Two Years After Acute Anterior Cruciate Ligament Injury Do Not Predict Structural Knee Osteoarthritis at Five Years

Objective: To determine the role of inflammatory biomarkers at 2 years post–anterior cruciate ligament (ACL) injury to predict radiographic knee osteoarthritis (OA) and magnetic resonance imaging (MRI)–defined knee OA at 5 years postinjury, with a secondary aim of estimating the concordance of inflammatory biomarkers assessed by MRI and synovial fluid (SF) analysis. Methods: We studied 113 patient

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes : A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation.

OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

Will this hemodynamically unstable patient respond to a bolus of intravenous fluids?

IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

Serum-free retinal explant culture system and comparative rescue effects of LEDGF, GST, CNTF, BDNF, NGF, bFGF and antioxidants in the rd1 mouse model of retinitis pigmentosa

Retinitis pigmentosa is a group of inherited retinal degenerative diseases characterized by the loss of photoreceptors and vision for which no effective treatment is available. Several animal models of retinitis pigmentosa are used to elucidate its pathogenesis and to devise therapies. The retinal degeneration (rd1) mouse is one such animal model in which rod-specific phosphodiesterase (PDE) is in

Ophthalmologic Outcome of Extremely Preterm Infants at 6.5 Years of Age : Extremely Preterm Infants in Sweden Study (EXPRESS)

Importance: This follow-up study of extremely preterm (EPT) children (<27 weeks' gestational age [GA] at birth) revealed major eye and visual problems in 37.9% (147 of 388) of all EPT infants and in 55.4% (67 of 121) of the most immature subgroups at 6.5 years of age. These major eye and visual problems were strongly associated with treatment-requiring retinopathy of prematurity (ROP).Objectives:

Slutrapport suhfs expertgrupp for kvalitetsfragor

Äntligen har jag kommit igång med rapportarbetet SLUTRAPPORT FRÅN SUHF:s EXPERTGRUPP FÖR KVALITETSFRÅGOR 2012-2013 Oktober 2013 1 Förord Mandatperioden 2012-2013 för SUHF:s expertgrupp för kvalitetsfrågor går mot sitt slut. Som framgår av rapportens titel är detta gruppens slutrapport för denna period. Rapporten består av en huvudtext och ett antal bilagor. Expertgruppen svarar för huvudtexten, me

https://www.lu.se/sites/www.lu.se/files/slutrapport_suhfs_expertgrupp_for_kvalitetsfragor.pdf - 2026-05-20

Information for doctoral students and departments about the public defence of doctoral theses-151016

Brevmall Facul ty Of f ice Helen W iman, Facul ty coord inator Information for doctoral students and departments about the public defence of doctoral theses Requesting a date for the public defence and booking a room The public defence of a thesis is to take place during the semester and the department (supervisor) is responsible for requesting a date for the public defence of a doctoral thesis. T

https://www.soc.lu.se/en/sites/soc.lu.se.en/files/information_for_doctoral_students_and_departments_about_the_public_defence_of_doctoral_theses-151016.pdf - 2026-05-20

A preanalytic validation study of automated bone scan index : Effect on accuracy and reproducibility due to the procedural variabilities in bone scan image acquisition

The effect of the procedural variability in image acquisition on the quantitative assessment of bone scan is unknown. Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). Methods: Two separate preanalytical studies were performed:

Street-level greenery mapping and urban heat modelling using deep learning and street view imagery

In an urbanizing world, challenged by climate change and rising temperatures, street vegetation can help mitigate urban temperatures. However, scaling the understanding of street vegetation’s cooling effects from local observations to the city level introduces challenges. While several studies have assessed the influence of street greenery on land surface temperature (LST) at the city scale using

Dok1

Brevmall STUDIEPLAN (Beslut) Dnr G11 S 2007/216 2007-05-31 Samhäl lsvetenskapl iga faku l te ten Inst i tu t ionen för ku l turgeograf i och ekonomisk geograf i Allmän studieplan för utbildning på forskarnivå till doktorsexamen i kulturgeografi/ekonomisk geografi och geografi med kulturgeografisk inriktning Studieplanen är fastställd av samhällsvetenskapliga fakultetsstyrelsen 2007-05-31, dnr G 11

https://www.keg.lu.se/sites/keg.lu.se/files/dok1.pdf - 2026-05-20

Caesarean section rates in public vs private hospitals in Europe : a systematic review and meta-analysis using the Robson ten group classification system

INTRODUCTION: Since the last two decades, there has been a dramatic rise in caesarean sections (CS) throughout the world. This increase has been seen even in Europe, where rates vary significantly from 17% in Northern Europe to 56% in the South. Although, CS can be a lifesaving intervention when medically necessary, non-essential CS are associated with short- and long-term complications for both t

2009 saob

FOLDER Svenska Akademiens ordboksredaktion har funnits i Lund sedan starten 1884. Dagens redaktion består av 22 personer. Knappt hälften redigerar, de övriga förbereder materialet, korrekturläser och kon- trollerar manuskript. Ordbokens hus på Dalbyvägen 3 innehåller förutom tjänsterum redaktionens arkiv och bibliotek. Till ordboksredaktionen är knutna en lång rad sakkunniga och experter. De hör h

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2009_saob.pdf - 2026-05-20

General Syllabus For Third Cycle Studies In Music, For Admitted 2024-2025

Faculty of Fine and Performing Arts , Malmö Reg. no: U 2024/692 General Syllabus for Third Cycle Studies in Music leading to a Degree of Doctor of Philosophy in Fine Arts 1. Programme details Programme and specialisation: Third cycle studies in Music Code: KOKOMUS1 Credits: 240 Cycle: Third Degree title: Doctor of Philosophy in Fine Arts in Music Degree title in Swedish: Konstnärlig doktorsexamen

https://www.arts.lu.se/sites/arts.lu.se/files/2026-04/General%20syllabus%20for%20third%20cycle%20studies%20in%20Music,%20for%20admitted%202024-2025.pdf - 2026-05-20

Minutes GS Board 240418

Graduate School Graduate School Board, 2024-04-18 In attendance Board members Lena Karlsson Director of Studies, Graduate School Leysan Storie Program Director, Politics and Society of the Contemporary Middle East Catia Gregoratti Program Director, Global Studies Marta Kolankiewicz Program Director, Social Studies of Gender Christopher Swader Program Director, Social Scientific Data Analysis Mikha

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2024-05/Minutes%20GS%20Board%20240418.pdf - 2026-05-20