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AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as
We investigated the quality of life (QoL) of newly diagnosed persons with cancer aged 65 years at baseline and 3 months after, in relation to age, contact with the healthcare system, activities of daily living, hope, social network and support using the European Organization for Research and Treatment of Cancer QLQ-C30, Katz ADL, Nowotny's Hope Scale, and the Interview Schedule for Social Interact
Purpose: Dronedarone may increase digoxin plasma levels through inhibition of P-glycoprotein. Using real-world data, we evaluated the risk of digitalis intoxication in concomitant users of dronedarone and digoxin compared digoxin-alone users. Methods: We used the Clinformatics DataMart, a US claims database, to identify adult patients with atrial fibrillation (AF) or atrial flutter (AFL) who conco
Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. The main component identified in these protein-rich deposits is the pAmyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. The main component identified in these protein-rich deposits is the p
Background: Acute type B aortic dissection (AoD) with malperfusion is a rare and complex disease. In this specific setting, invasive treatment is generally required to improve aortic branch vessel flow. Thoracic aorta stent grafting (TEVAR) of the proximal descending thoracic aorta to cover/exclude the proximal intimal entry tear would promote resolution of the dynamic component (the most prevalen
“The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. In the often very emotionally-led debate basically two directly conflicting schools of thoughts can be identified. Some people believe
Background: According to the “brain-reserve hypothesis” in Alzheimer’s disease (AD), patients with more years of education are expected to have higher cognitive status during adulthood. Hence, they might have a relatively larger burden of AD pathology and a more advanced level of the disease when dementia is clinically evident. Higher educated people would also be expected to perform better on sta
The delay or refusal of vaccination, which defines vaccine hesitancy, is a major challenge to successful control of COVID-19 epidemic. The huge number of publications addressing COVID-19 vaccine hesitancy necessitates periodic review to provide a concise summary of COVID-19 vaccine acceptance rates worldwide. In the current narrative review, data on COVID-19 vaccine acceptance rates were retrieved
As smart and as stupid, as well- and ill-informed, as curious and closed-minded as any random sample, tourists represent a unique object of study, as they are “the last remaining class that exhibits consciousness for itself” (MacCannell, 2013 p.xix). Technology has been transforming the tourist experience deeply, as it both fulfils a functional purpose of performing tasks for humans, and it holds
The purpose of this study was to investigate the early alterations of retinal function, assessed with electrophysiology, in newly onset type 2 diabetes patients without vascular retinopathy. Seventeen patients with newly diagnosed type 2 diabetes (duration 7 ± 3 months), without any vascular retinopathy in fundus photographs, were examined with full-field electroretinogram (ERG) and multifocal ERG
Background Orthognathic surgery addresses facial aesthetics and function in patients with dentofacial deformities. It is associated with changes in upper airway volume (UAV). If changes in UAV is perceived by asymptomatic patients is unclear. Purpose The purpose was to measure associations between changes in UAV and patient-reported benefits using patient-reported outcome measures (PROM). Study de
Many universities are actively promoting scholarly inquiry into teaching and learning to improve education. Strategies used may involve support for development projects, teaching awards and academies. The Faculty of Medicine, Lund University, Sweden, has developed a Teaching Academy with criteria for membership founded in Scholarship of Teaching and Learning (Kreber, 2002; Trigwell & Shale, 20
This Theoretical Foundations Report has been developed for UNDP’s Conscious Food Systems Alliance (CoFSA). It demonstrates the need for increased policy attention to the neglected inner dimension of sustainability to address today’s sustainability crises. In addition, it provides an overview of current research and evidence for the potential of consciousness approaches and practices to complement
This article explores the emotional challenges of digital documentation practices in child protection social work. Drawing on ethnographic fieldwork in Swedish social services, it explores how social workers negotiate organisational and professional feeling rules when performing child protection investigations using a digital documentation-based structure. Theoretically informed by Arlie HochschilThis article explores the emotional challenges of digital documentation practices in child protection social work. Drawing on ethnographic fieldwork in Swedish social services, it explores how social workers negotiate organisational and professional feeling rules when performing child protection investigations using a digital documentation-based structure. Theoretically informed by Arlie Hochschil
BACKGROUND: Tuberculosis remains a leading infectious cause of death in resource-limited settings. Effective treatment is the cornerstone of tuberculosis control, reducing mortality, recurrence and transmission. Supporting treatment adherence through facility-based observations of medication taking can be costly to providers and patients. Digital adherence technologies (DATs) may facilitate treatm
DNA is presently at the centre of a storm. On the one hand, the breathtaking development of DNA related sciences during the last decades led to a technological and medical revolution. Due to the far reaching possibilities connected to this technology, it is the focus of many people’s interest and one source of the hope that one day we will find cures for terrible illnesses. Unsurprisingly, DNA re
I uppsatsen behandlas domstolars bedömning av orsakssambandet mellan hälso- och sjukvårdspersonalsstraffrättsliga oaktsamhet och patienters skador eller död. Vårdpersonal är inte undantagna det straffansvar som följer av brottsbalken. Det är dock ovanligt att åtal väcks mot personal inom hälso- och sjukvården och det är ännu mer ovanligt med fällande domar i de fall som prövats av domstol. Detta bThe present study examines the court's evaluation of the causal relationship between the criminal negligence of healthcare professionals and the subsequent injury or death of patients. Healthcare professionals are not exempt from criminal liability under the Criminal Code. However, prosecutions of healthcare professionals are uncommon, and convictions in cases tried by the courts are even rare
In the spring of 2015, five young feminist activists were arrested by the Chinese police for allegedly ‘causing trouble’, which resulted in global attention aimed at this new wave of feminist movement. Youth feminist activism have made their voice heard in China through numerous actions for gender equality since 2012. Not much is known about the new feminist movements and the limited work that exi
