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Background: Insulin is a therapeutic protein that is widely used for the treatment of diabetes. Its biological function was discovered more than 80 years ago and it has since then been characterized extensively. Crystallization of the insulin molecule has always been a key activity since the protein is often administered by subcutaneous injections of crystalline insulin formulations. Over the year

Popular Abstract in Swedish Proteiner är biologiska molekyler som kan utvinnas ur olika bakterier, svampar, djur och människor. I sin naturliga miljö bidrar de bl. a. till att katalysera (snabba på) olika kemiska reaktioner (enzymer), att sköta transporten av olika molekyler, bidra till immunförsvaret och tillväxtkontroll (hormoner). Upptäckten att proteiners olika funktion kan uttnyttjas i många The effect of different additives on protein stability was studied, and the basis for stabilization was investigated at molecular level. The addition of sorbitol enhanced thermal stability of hen egg white lysozyme in aqueous solution. NMR spectroscopy revealed changes in the relaxation properties of Ala and Thr methyl groups in lysozyme, indicating compression of the enzyme as a consequence of pr

The over-riding aim of this thesis was to obtain a deeper understanding of the way patients with cardiac problems view both information related to their health and medical decisions and their role in decision-making processes. An important objective was to identify reasons why patients do not ask for or assimilate information or why they do not want or feel that they are able to influence medical

Den här avhandlingen presenterar nya metoder och tekniker som utvecklats för att undersöka nanotrådars (NT) och NT-enheters egenskaper, och de resultat som erhållits med dessa. Växt och karakterisering av NT har blivit en stor forskningsområde då NT har visat sig förbättra egenskaperna hos många tillämpningar inom halvledarteknologin, såsom transistorer, solceller och lysdioder. Strukturell sammanThis dissertation presents the new methods and techniques developed to investigate the properties of nanowires (NWs) and NW devices and the results obtained using these methods. The growth and characterization of NWs have become a large research field because NWs have been shown to improve the properties of many semiconductor applications such as transistors, solar cells, and light emitting diodes

Migratory songbirds carry an inherited capacity to migrate several thousand kilometers each year crossing continental landmasses and barriers between distant breeding sites and wintering areas. How individual songbirds manage with extreme precision to find their way is still largely unknown. The functional characteristics of biological compasses used by songbird migrants has mainly been investigat

Objective: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all ischemic stroke and is a major manifestation of cerebral small vessel disease, the primary cause of vascular cognitive impairment. Studies across neuro

Från år 2021 ska alla nybyggnationer i Europa vara nära-nollenergibyggnader. Detta innebär att byggnaders energianvändning bör vara låg och i mycket hög grad tillförs i form från förnybara energikällor som produceras på plats eller i närheten. Syftet med de höga energikraven är att påskynda takten för att skapa ett mer energieffektivt byggande. Den minskade energianvändningen tillsam-mans med en öFrom year 2021, all new buildings in Europe will be net zero-energy buildings. This means that the building's energy is supplied from renewable energy sources that are produced on site or nearby. The purpose of the high energy requirements is to accelerate the pace of creating more energy-efficient constructions. The reduced energy consumption, together with increased use of renewable energy,

Nyfikenhet om stjärnorna och galaxerna runt om oss har fascinerat civilisationer i tusentals år. Rörelsen, ljuset, och mönster av himlakroppar har studerats av astronomer som försker förstå universum och dess utveckling. En fascinerande aspekt av studien av ljuset som emitteras från avlägsna stjärnor är att man observerar det förflutna. Dessutom är det detta ljus och strålning som flyr stjärnorna To understand the evolution of our galaxy, the chemical abundance patterns and trends within the stars of the different regions are explored. The process of synthesizing these elements reveals key details about the way the stars and, therefore, the galaxy formed. This project focused on the element potassium, K, and specifically its absorption line 7699 Å. The local thermodynamic equilibrium (LTE)

Syftet med denna uppsats är att problematisera Pensionsmyndighetens externa kommunikation, mer specifikt informationskampanjen Riskgruppen, och analysera på vilka sätt den kan förstås som producerad i en nyliberalistisk diskurs. Inom ramen för detta syfte problematiseras vad en nyliberalistisk diskurs kan sägas kännetecknas av och vilken “konceptuell logik”, d.v.s. de värderingar och förgivettagna

I den första sektionen av denna uppsats behandlas hur alkohol- och drogmissbruk inverkar på bedömningen av grund för uppsägning eller avsked. De lagbestämmelser som är aktuella i denna del finns framförallt i lagen om anställningsskydd, arbetsmiljölagstiftningen samt socialförsäkringsbalken. Sjukdom utgör som huvudregel inte saklig grund för uppsägning utan arbetsgivaren har en skyldighet att förs

Denna uppsats ämnar till att undersöka vilka faktorer som påverkar intentionen hos icke adoptanter mellan 18–30 år till att använda sig av Personal Financial Management-tjänster i Sverige. Detta undersöks med stöd av teorierna TechnologyAcceptance Model och Diffusion of Innovation, vilket resulterar i en modell av sju faktorer som enligt tidigare studier haft signifikant påverkan på liknande digit

Uppsatsen behandlar ämnet slöjförbud i Sverige. Syftet är att undersöka hur en svensk partipolitiskt obunden organisation, som arbetar med hedersrelaterat våld och förtryck, konstruerar deras ståndpunkter om slöjförbudet samt hur de tillförskriver attribut till slöjbärande kvinnor som kan bli påverkade av slöjförbud. Materialet består av en skrift från den slöjkritiska organisationen ”Glöm aldrig The subject in this thesis is ban of veils in Sweden. The aim of this thesis is to examine how a Swedish non-party political organization, that works with honor related violence and oppression, constructs their positions about a ban of the veil, and further how they prescribe attributes to veiled women who can be affected by the ban. The analyzed material is a publication from the Swedish veil-cri

In recent years, low-cost flights to smaller cities in Central and Eastern Europe grew fast. This growth offered tourists new possibilities to explore new, lesser-known destinations at a low price. At the same time, urban tourism is a common strategy for urban regeneration and development in Central and Eastern Europe, and therefore, a significant factor of the economic restructuring of Post-Socia

This thesis investigates the free boundary value problem of pricing American put options written on one underlying asset. In particular, attention is given to nd an accurate approximation of the critical ex- ercise boundary. The problem is approached using radial basis func- tions in the shape of Gaussian densities, and basis functions in the form of European put options. Furthermore, the domain i

Title: Technology – the link between network effects and diversification Seminar date: 2013-06-07 Course: FEKH19, Degree project Undergraduate level, Strategic Management, 15 University Credits Points Authors: Carolina Edvinsson, Adam Lindroth, Andreas Walberg, Laura Waldenström Advisor: Matts Kärreman Key words: Network effects, Diversification, Industry convergence, Technological platforms, Inno

A Linear e+e- collider, either ILC or CLIC will be the next platform for high energy physics study to complement the LHC. Results discovered by LHC may need precision measurements before we can get full understanding of the physics. International collaborations are in the process to prepare both for the accelerator and for the experimental setup. Time projection chambers as the main central track

In online auctions bidding frequency tends to increase towards the last minutes of the auction. This thesis investigates why bidders might choose to engage in last minute bidding, sniping, in Tradera auctions (Tradera is a Swedish subsidiary of eBay). Tradera uses a hard-close rule and a second-price rule. In hard-close auctions the dead-line occurs at a specific time, after which new bids are not

The topic of this thesis deals with the implementation deficit in the environmental sector that exists within the EU. According to the 25th annual, report from the Commission, there were over 3400 complaints and infringement files under 2007. The environmental sector was the area with the highest number of open cases that concerned non-compliance in 2006 Sweden is however one of the best Member St

The human race has for a long time contributed to an increase of the environmental problems, however in recent times they have begun to deploy measures to counter this. One of these measures is environmental classification systems, which is used in the construction- and property sector. Environmental classification systems are methods which evaluate a building's environmental performance in or