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Protein structure-function relationships can be studied by using linker insertion mutagenesis, which efficiently identifies essential regions in target proteins. Bacteriophage Mu in vitro DNA transposition was used to generate an extensive library of pentapeptide insertion mutants within the alpha-complementing domain 1 of Escherichia coli beta-galactosidase, yielding mutants at 100% efficiency. E
Background. To evaluate the relationship between age and poor ovarian response to pregnancy and cancellation rate after IVF stimulation. Methods. Poor ovarian response was defined as <= 5 follicles at ovum pick up (OPU). Out of 1,706 consecutive OPUs performed during 2003/2004, 290 poor responders were identified. This cohort of poor responders was divided into two groups, 'older' and 'younger', w
Popular Abstract in Swedish Avhandlingen kretsar kring centralbankens möjligheter att kontrollera inflationstakten. Under senare tid har mycket forskning ägnats åt att analysera och utvärdera de institutionella förutsättningarna för centralbanker, såväl avseende graden av oberoende som vilka mål penningpolitiken bör inriktas mot; exempelvis direkta inflationsmål versus användandet av indirekta målAfter an introductory chapter, the hypothesis is made in chapter two: that central bank power to control the rate of inflation rests on the bank’s ability to achieve a role as a focal point for inflation. Inflation is a measure of changes in the general price level, the price level is an index of individual prices, and to predict future price levels is thus to predict future prices on individual i
Uppsatsen behandlar barns rättsliga ställning i familjerättsliga mål, LVU-mål och asylmål. Arbetet syftar till att undersöka de likheter och skillnader som föreligger mellan dessa typer av processer. Det förekommer att barn kan vara inblandade hos flera myndigheter och domstolar samtidigt. Det kan handla om en vårdnadstvist mellan vårdnadshavarna i tingsrätten, samtidigt som det finns en begäran oThe essay deals with legal status of children in family law cases, LVU cases, and asylum cases. This work aims to investigate the similarities and differences that exist between these types of processes. It happens that a child may be involved with several governments and courts at the same time. This may involve a custody dispute between the legal guardians, in the district court, while there is
Title: Pawnshop of hearts? – The dynamics of identification and meaning creation in a property management organization. Submission Date: 22nd of May 2013 Course: BUSN49- Degree Project in Managing People, Knowledge and Change (Master level) Authors: Linnea Hansson and Mathilda Welin Brook Supervisors: Jens Rennstam and Stephan Schaefer Department of Business Administration School of Eco
Inom barnhälsovården i Landskrona-Lund-Orup görs en språklig screeningundersökning i samband med 2,5-årskontrollen. Det finns intresse av att ännu tidigare hitta de barn som löper risk för allvarliga språk- och kommunikationssvårigheter. Normalvariationen i den tidiga utvecklingen är stor och det är svårt att före 2,5 års ålder identifiera barn som löper risk för språkstörning. En del av de barn s
Despite numerous challenges, since its independence, Uzbekistan, with the exception of the May 2005 Andijan events, has enjoyed extraordinary political stability and not recorded any considerable cases of interethnic or interfaith conflict, regime change or civil war, whereas neighboring Kyrgyzstan, labeled an “island of democracy” by the Western world, has experienced numerous conflicts and chaos
Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and neovascularization. Pericytes constitute an important part of the GBM microvasculature. The contribution of endogenous brain pericytes to the tumor vasculature in
Popular Abstract in Swedish Benskörhet (osteoporos) är ett tillstånd som definieras av låg benmassa och ökar med stigande ålder. Osteoporos är idag en av de stora folksjukdomarna och man räknar med att en tiondel av alla män och en fjärdedel av alla kvinnor i Sverige drabbas. Tillståndet är i sig symptomfritt men ökar risken att råka ut för ett benbrott (fraktur) redan vid lättare fall. Frakturer The aim of this thesis was to evaluate risk factors for bone fragility and fractures in postmenopausal women in a long-term perspective. The study period spanned from the age of 48 to age 82 and is thus unique in its length. The studied sample was homogeneous and consisted of 390 north European women from a population-based cohort. At the start of the study, general health and lifestyle parameters
Glacifluvial deposits along an ice-marginal zone,in Smaland, southern Sweden, have been dated using post-IR blue OSL. To test for incomplete bleaching, we adopted two strategies: analysis of modern analogues and small-aliquot dose distributions. Samples of modern fluvial sediments show no significant incomplete bleaching; they yield equivalent doses of only 0.5-2 Gy (similar to 0.25-4% of our glac
The fire-bellied toad (Bombina bombina) is an amphibian that since its national classification as an endangered species in 2005 (NT- Near Threatened) has increased in population size and distribution. Today the population in Sweden is considered viable since 2010 (LC- Least Concern) and it is possible that constructed wetlands in Scania have had positive effects on the fire-bellied toad. The impor
The purpose of this Master’s Thesis was to examine different usage applications for animations and to develop one or several animated products for Sony Ericsson Mobile Communications AB. The overall objective was to develop an animated tool for information purposes and to investigate different interesting fields of application for the animated products. The goal was also to show the procedure of c
I media har vid flera tillfällen fall av oegentligheter vid företagsförvärv uppmärksammats. Det kanske mest uppseendeväckande fallet är den så kallade Trustorhärvan. Det som hände i Trustor var att köparen lyckades förvärva bolaget utan att ha en egen förmåga att finansiera köpet. Denna typ av förvärvstransaktioner är naturligtvis mycket riskabla utifrån borgenärsperspektiv och därför förbjudna enSeveral cases of irregularities related to acquisitions of companies have been portrayed in the media. Perhaps the most striking case is the so-called Trustor Affair. What happened in Trustor was that the buyer managed to acquire the company without having any own ability to finance the purchase. These types of transactions are extremely risky for the company’s creditors, and therefore prohibited
Abstract: The controversial issue of ‘missing girls’ has been a cause of concern since the time of the British rule in India. Most research studies pointed towards a demographic pattern of its occurrence, the Northwestern plains of India saw an alarming scarcity of girl children. Since then many studies focused at examining the economic and socio-cultural factors motivating the missing girl phenom
Syfte: Syftet med vår studie är att beskriva och analysera utformning av organisation och styrning av akutkliniker. Det är också att undersöka huruvida specifika arbetssätt utmärker sig och utifrån detta skapa ett underlag för framtida diskussion rörande organisation och styrning av akutsjukvård. Metod: Uppsatsens metod grundar sig i en kvalitativ undersökningsdesign där multipla fallstudier anväPurpose: The purpose of this thesis is to describe and analyze the organization of and control tools used at emergency clinics. Futhermore it aims explore whether any methods are better than others to ease the patients’ process through the organization and create a basis for further discussion. Methodology: The thesis method is based on a qualitative research design where multiple case studies ha
Med ökad andel intermittent elproduktion i Sveriges elproduktionsmix och ett åldrande stamnät ökar behovet av flexibilitet i elsystemet. Lagring av energi, till exempel i vätgas, är ett exempel på en sådan flexibilitetslösning, eftersom energin kan flyttas från tidpunkter med överskott till tidpunkter med högt energibehov. Syftet med examensarbetet är att undersöka energisystemnyttan med ett v ägaSweden’s increasing share of intermittent electricity production and aging backbone network has given rise to a need for flexibility in the energy system. A potential solution to this challenge is energy storage, where hydrogen is a possible pathway. This master’s thesis aims to investigate the energy system benefits of a hydrogen system for seasonal energy storage of excess solar electricity in a
År 2013 initierades BEPS-projektet av OECD, vilket syftar till att motverka skatteflykt och erodering av skattebaser. En av projektets åtgärdspunkter (nummer 7) har till ändamål att förändra definitionen av vad som utgör ett fast driftställe enligt OECD:s modellavtal. Den nuvarande definitionen av ett fast driftställe har varit i stort sett oförändrad sedan den infördes i modellavtalet 1963. I taThe OECD initiated the BEPS project in 2013 with the purpose of eliminating tax avoidance and profit shifting. One of the actions in the project aims to change the current definition of permanent establishments in the OECD model convention, especially concerning dependent and independent agents. The current definition of a permanent establishment has, with the exception of minor changes, been in
Sugardating innebär att någon - oftast en äldre man – på olika sätt betalar en annan – oftast en yngre kvinna – för umgänge och intimitet. Köp av sexuella tjänster är kriminaliserade i svensk rätt, men rättsordningen har än så länge inte tagit ställning till hur köpandet av känslomässig intimitet ska hanteras rättsligt. Den här uppsatsen diskuterar hur rättsordningen på olika sätt befattar sig, elSugardating constitutes the practise when someone – most commonly an older man – in different ways pays another – most commonly a younger woman – for company and intimacy. While paying for sexual services is illegal in Swedish law, buying the service of emotional intimacy is left without interference from the legal system. This essay will discuss how sugardating agreements are being managed, or sh
This thesis discusses modeling and implementation of reconfigurable hardware architectures for real-time applications. The target application in this work is digital holographic imaging, where visible images are to be reconstructed based on holographic recordings. The reconstruction process is computationally demanding and requires hardware acceleration to achieve real-time performance. Thus, this
Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. Since galectins have been implicated in mechanisms of both chronic inflammation and cancer, we have inves
