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Androgens in women after allogeneic hematopoietic cell transplantation : Impact of chronic GvHD and glucocorticoid therapy

Low androgen levels may contribute to sexual dysfunction in women after allogeneic hematopoietic cell transplantation (alloHCT). However, data on serum androgens in women after alloHCT are limited. The aim of this study was to assess androgen levels and their association with chronic GvHD (cGvHD) and glucocorticoid (GC) therapy. Included were 65 allografted women, 33 with cGvHD, and 23 of these we

Konstruktion av skrovventil

The goal of this thesis was to design a Multiple Hull Valve (MHV) with the purpose to increase the safety and decrease the amount of hull penetrations in a submarine. The safety is improved by a double shut of function where the outer plate valve is closed by the pressure difference in case of failure. A great advantage with the MHV is that the systems in an early stage are protected from both mar

A Concept Proposal of a New Generation Operator Panels

This project was done for the company Beijer Electronics Products AB and the task was given by the hardware development department of the company. The project was about developing a concept proposal for a new generation operator panels. This was done to inspire the product developers at Beijer Electronics with innovative ideas before the actual operator panel development. More in detail the object

Seeking support: insights into women’s mental health help-seeking behavior in Bangladesh

Introduction: Depression and anxiety are leading contributors to the global burden of disease among women yet help-seeking for mental health concerns remains limited in lower-middle-income countries. This study aimed to estimate the prevalence of anxiety, depression, and help-seeking behaviors, and to identify factors associated with the absence of help-seeking among ever-married women of reproduc

An ultra-short period super-Earth and sub-Neptune spanning the Radius Valley orbiting the kinematic thick disc star TOI-2345

A crucial chemical link between stars and their orbiting exoplanets is thought to exist. If universal, this connection could affect the formation and evolution of all planets. Therefore, this potential vital link needs testing by characterizing exoplanets around chemically-diverse stars. We present the discovery of two planets orbiting the metal-poor, kinematic thick-disc K-dwarf TOI2345. TOI-2345

‘Ghost’ fossils of early coccolithophores point to a Triassic diversification of marine calcifying organisms

Over geologic time, biocalcification – the process by which marine organisms make calcium carbonate (CaCO3) – has reshaped climates, ocean life, and seawater chemistry. In particular, the evolution of coccolithophores, the largest group of nannoplankton and today’s most productive calcifiers, transformed ocean environments and the carbon cycle. Their origins, however, remain enigmatic. This is par

Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias : A Nonrandomized Open-label Trial

A hybrid assistive limb (HAL) can improve the motor performance of patients with various neurodegenerative diseases, but the efficacy of home-based rehabilitation using HAL for spinocerebellar ataxias (SCA) has yet to be elucidated. To evaluate the efficacy and safety of home-based telerehabilitation with lumbar type HAL in patients with SCA. In this non-randomized open-label single center trial,

Longitudinal decline in upper-limb range of motion in adults with cerebral palsy

To analyse longitudinal changes in passive range of motion (ROM) in the upper limb in adults with cerebral palsy (CP). Method: Passive ROM for shoulder abduction and flexion, supination, and elbow and wrist extension was analysed in a longitudinal cohort of adults aged 16 to 76 years from the Swedish CP registry. Individual ROM trajectories and mean ROM curves were calculated using the Manual Abil

Gamma decay of high spin states in Mg25 above 6.1 MeV

New high spin states in Mg25 (up to 13.3 MeV in excitation) have been located using the N12,p)25Mg reaction at a laboratory beam energy of 23.5 MeV. Gamma decay from 28 neutron unbound levels has been observed (24 of which are reported here for the first time) up to 7 MeV above the neutron drip line. Tentative identification of the yrast line up to (17/2+ has been made, along with an extension of

Associations between the thermal spring timing variability and atmospheric teleconnection patterns over the past six decades in Finland

The timing of the spring season in the boreal region is shifting under global warming, with profound impacts on ecosystems and hydrological processes. However, the mechanisms driving this transition and its considerable interannual variability are not well described, especially regarding the influence of large-scale atmospheric teleconnection patterns. This study examines the temporal variability

Computational Evidence for a Water-Assisted Proton-Transfer Mechanism in Uronate Isomerase from Bacillus Halodurans (Bh0493)

Uronate isomerase (EC 5.3.1.12; URI) catalyzes uronate sugar interconversion, a key step in bacterial metabolism, yet its reaction mechanism remains poorly understood. This study delineates the detailed mechanism for the isomerization of d-glucuronate to d-fructuronate catalyzed by a Zn2+-dependent URI enzyme (from Bacillus halodurans). Using quantum mechanical (QM) cluster calculations, three mec

Heterogeneity between insulin and proinsulin in the potency for insulin autoantibodies (IAA) in newly diagnosed type 1 diabetes children

INTRODUCTION: Autoantibodies against insulin (IAA) are early appearing markers of autoimmunity against the pancreatic islet beta cells and predict progression to type 1 diabetes if additional islet autoantibodies also develop. It is still controversial if proinsulin rather than insulin is the primary autoantibody.METHODS: The aim of the present study was to compare the half-maximal concentration (

MIS 3 vast alluviation by the Białka River, and further implications to the Tatra glaciers and river incision.

Both high-mountain rivers and wet-based mountain glaciers are considered effective erosion agents. They acted alternatively or simultaneously during the late Quaternary in the Tatra Mountains (West Carpathians) thus producing a vast amount of clastic material that was subject to deposition, reworking and transportation downstream. A small fraction of that amount of the material is still preserved

Sverre Spoelstra

Professor Kontaktinformation E-post: sverre [dot] spoelstra [at] fek [dot] lu [dot] seOrganisation Organisation Rumsnummer: Alfa 1, vån 3, rum 3030 Hämtställe: 10 WebbplatsSverre Spoelstras profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftBokBokrecensionDel av eller Kapitel i bokKonferensb

https://www.ehl.lu.se/sverre-spoelstra - 2026-06-15

Hans Knutsson

Senior lecturer Contact details Email: hans [dot] knutsson [at] fek [dot] lu [dot] se Mobile: +46 73 399 41 72Organisation Strategy Room number: Alfa 5,6 rum B418 Service point: 10 WebpageHans Knutssons profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllBookBook chapterConference paperDissertationJournal articleLicentia

https://www.lusem.lu.se/hans-knutsson - 2026-06-15

Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer

The genetic changes underlying the development and progression of male breast cancer are poorly understood. Germline BRCA2 mutations account for a significant part of male breast cancer, but the majority of patients lack a known inherited predisposition. We recently demonstrated that the progression of breast cancer in female carriers of a germline BRCA1 or BRCA2 mutation follows specific genetic