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A measurement of the ratio of the W and Z cross sections with exactly one associated jet in pp collisions at root s=7 TeV with ATLAS
The ratio of production cross sections of the W and Z bosons with exactly one associated jet is presented as a function of jet transverse momentum threshold. The measurement has been designed to maximise cancellation of experimental and theoretical uncertainties, and is reported both within a particle-level kinematic range corresponding to the detector acceptance and as a total cross-section ratio
Integration potential, resource efficiency and cost of forest-fuel-based biorefineries
A multidisciplinary study of the implementation potential of a biorefinery, using forestry residues as feedstock, is performed by assessing techno-economic factors, system integration and feedstock supply. The process is based on biochemical conversion of logging residues to produce ethanol, biogas, pellets, heat and electricity. Nine models were designed in Aspen Plus based on the available feeds
Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring.
Prostate specific antigen (PSA) is a well-established tumor marker, which is frequently employed as model biomarker to develop and evaluate emerging quantitative proteomics techniques, partially due to wide access to commercialized immunoassays serving as "gold standard". We designed a multiple reaction monitoring (MRM) assay to detect PSA proteoforms in clinical samples (n=72), utilizing specific
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.
Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess the impact of rare and low-frequency variants. To determine whether rare or low-frequency coding variants are associated with LDL-C, we exome sequenc
Emotional reactions, perceived impact and perceived responsibility mediate the identifiable victim effect, proportion dominance effect and in-group effect respectively
This study investigated possible mediators of the identifiable victim effect (IVE), the proportion dominance effect (PDE), and the in-group effect (IGE) in helping situations. In Studies 1-3, participants rated their emotional reactions (distress and sympathy toward the victims), perceived impact of helping, perceived responsibility to help, and helping motivation toward four versions of a helping
A 10-bit 5-MS/s successive approximation ADC cell used in a 70-MS/s ADC array in 1.2-um CMOS
A 10-bit 5-MS/s successive approximation ADC cell and a 70-MS/s parallel ADC array based on this cell, designed and fabricated in a 1.2-?m CMOS process, are presented. The ADC cell was designed to have an input bandwidth of more than 35 MHz and a sampling time of 14 nS at a clock rate of 70 MHz. The parallel ADC array consists of 14 such cells which are timed in one clock cycle skew successively i
Genetic basis of the K phenotype in the Swedish population.
Abstract in Undetermined BACKGROUND: The absence of all Kell blood group antigens (K0 phenotype) is very rare. K0 persons, however, can produce clinically significant anti-Ku (K5) after transfusion and/or pregnancy and require K0 blood for transfusion. Ten alleles giving rise to the K0 phenotype have been reported: different populations were studied although none from Scandinavia. STUDY DESIGN AND
Element Design for Active Learning : A Design Thinking Approach to Assignment Development for Political Science, Media, and Communication Education
Hundreds of active learning assignments are reported in the political education literature. However, the adaptability of these assignments to new courses can be limited by different learning outcomes, course themes, or institutional contexts. To assist educators in developing assignments that align with their teaching needs, this study introduces the concept of element design. Element design refer
Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA.
Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard reagent panel. The panel was designed by a group of HPV experts, and samples were prepared and distributed by the World Health Organization International Laboratory for Standards and Biologicals in The Ne
Captured metagenomics: large-scale targeting of genes based on 'sequence capture' reveals functional diversity in soils.
Microbial enzyme diversity is a key to understand many ecosystem processes. Whole metagenome sequencing (WMG) obtains information on functional genes, but it is costly and inefficient due to large amount of sequencing that is required. In this study, we have applied a captured metagenomics technique for functional genes in soil microorganisms, as an alternative to WMG. Large-scale targeting of fun
Full-Scale Ultimate-Load Test of a Stress-Laminated-Timber Bridge Deck
A general assumption reported in the literature is that the structural response of a stress-laminated-timber (SLT) bridge deck is linear until failure. However, few studies of ultimate-load tests (ULTs) on timber bridges have been reported. A full-scale test of a SLT deck (span, 4.9 m; thickness, 270 mm) was performed to obtain the deformations at various prestress levels as well as at the ultimat
Association measures of claims-based algorithms for common chronic conditions were assessed using regularly collected data in Japan
OBJECTIVE: Although claims data are widely used in medical research, their ability to identify persons' health-related conditions has not been fully justified. We assessed the validity of claims-based algorithms (CBAs) for identifying people with common chronic conditions in a large population using annual health screening results as the gold standard.STUDY DESIGN AND SETTING: Using a longitudinal
Age-based entitlement : An ageist practice or a tool for combatting ageism?
Researchers in gerontology have addressed the way age-based arrangements may communicate stereotypical and devaluing images of older people, thereby linking high age to frailty and dependence. The present article considers proposed reforms to the Swedish eldercare system designed to guarantee people over 85 the right to move into a nursing home regardless of their needs. The purpose of the article
A Backend Extension Mechanism for PQL/Java with Free Run-Time Optimisation
In many data processing tasks, declarative query programming offers substantial benefit over manual data analysis: the query processors found in declarative systems can use powerful algorithms such as query planning to choose high-level execution strategies during compilation. However, the principal downside of such languages is that their primitives must be carefully curated, to allow the query p
Creating space, aligning motivations, and building trust: a practical framework for stakeholder engagement based on experience in 12 ecosystem services case studies
Ecosystem services inherently involve people, whose values help define the benefits of nature's services. It is thus important for researchers to involve stakeholders in ecosystem services research. However, a simple and practicable framework to guide such engagement, and in particular to help researchers anticipate and consider key issues and challenges, has not been well explored. Here, we use e
The prognostic performance of lactate in out of hospital cardiac arrest, a post hoc analysis of the TTM-trial
Designing bimanual tangible interaction for stroke survivors
Stroke is a significant cause of long-term disability, impairing over 10 million peoples motor function, primarily on one side of the body every year. Whilst effective rehabilitation exercises can help recover and maintain some affected motor function, stroke survivors often do not carry out enough of these. Instead relying on their `good' side to carry out tasks. However, this leads to poor recov
From whole bodies to single cells : A guide to transcriptomic approaches for ecology and evolutionary biology
RNA sequencing (RNAseq) methodology has experienced a burst of technological developments in the last decade, which has opened up opportunities for studying the mechanisms of adaptation to environmental factors at both the organismal and cellular level. Selecting the most suitable experimental approach for specific research questions and model systems can, however, be a challenge and researchers i
Gene expression and nucleotide composition are associated with genic methylation level in Oryza sativa
BACKGROUND: The methylation of cytosines at CpG dinucleotides, which plays an important role in gene expression regulation, is one of the most studied epigenetic modifications. Thus far, the detection of DNA methylation has been determined mostly by experimental methods, which are not only prone to bench effects and artifacts but are also time-consuming, expensive, and cannot be easily scaled up t
