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Everyday Encounters with Deepfakes : Young People’s Media and Information Literacy Practices with AI-Generated Media

PurposeThis research aims to contribute to the knowledge related to youth’s media and information literacy (MIL) practices when encountering artificial intelligence (AI)-generated media in their everyday life. It specifically examines young people’s engagement with and understanding of deepfakes, seeking to explore their practices for navigating deepfakes in a daily setting.Design/methodology/appr

Genetic basis of the K phenotype in the Swedish population.

Abstract in Undetermined BACKGROUND: The absence of all Kell blood group antigens (K0 phenotype) is very rare. K0 persons, however, can produce clinically significant anti-Ku (K5) after transfusion and/or pregnancy and require K0 blood for transfusion. Ten alleles giving rise to the K0 phenotype have been reported: different populations were studied although none from Scandinavia. STUDY DESIGN AND

A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide

We report the development of a high-level bacterial expression system for the Alzheimer's disease-associated amyloid beta-peptide (A beta), together with a scaleable and inexpensive purification procedure. A beta(1-40) and A beta(1-42) coding sequences together with added ATG codons were cloned directly into a Pet vector to facilitate production of Met-A beta(1-40) and Met-A beta(1-42), referred t

Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA.

Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard reagent panel. The panel was designed by a group of HPV experts, and samples were prepared and distributed by the World Health Organization International Laboratory for Standards and Biologicals in The Ne

Hypnotic treatment synergizes the psychological treatment of fibromyalgia: A pilot study

In this pilot study, we compare the efficacy for fibromyalgia of multimodal cognitive behavioral treatments, with and without hypnosis, with that of a purely pharmacological approach, with a multiple baseline N = 1 design. We randomly assigned six hospital patients to the three experimental conditions. The results suggest that psychological treatment produces greater symptom benefits than the conv

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.

Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess the impact of rare and low-frequency variants. To determine whether rare or low-frequency coding variants are associated with LDL-C, we exome sequenc

Captured metagenomics: large-scale targeting of genes based on 'sequence capture' reveals functional diversity in soils.

Microbial enzyme diversity is a key to understand many ecosystem processes. Whole metagenome sequencing (WMG) obtains information on functional genes, but it is costly and inefficient due to large amount of sequencing that is required. In this study, we have applied a captured metagenomics technique for functional genes in soil microorganisms, as an alternative to WMG. Large-scale targeting of fun

Full-Scale Ultimate-Load Test of a Stress-Laminated-Timber Bridge Deck

A general assumption reported in the literature is that the structural response of a stress-laminated-timber (SLT) bridge deck is linear until failure. However, few studies of ultimate-load tests (ULTs) on timber bridges have been reported. A full-scale test of a SLT deck (span, 4.9 m; thickness, 270 mm) was performed to obtain the deformations at various prestress levels as well as at the ultimat

Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring.

Prostate specific antigen (PSA) is a well-established tumor marker, which is frequently employed as model biomarker to develop and evaluate emerging quantitative proteomics techniques, partially due to wide access to commercialized immunoassays serving as "gold standard". We designed a multiple reaction monitoring (MRM) assay to detect PSA proteoforms in clinical samples (n=72), utilizing specific

New features of the MAX IV thermionic pre-injector

The MAX IV facility in Lund, Sweden consists of two storage rings for production of synchrotron radiation. The smaller 1.5 GeV ring is presently under construction, while the larger 3 GeV ring is being commissioned. Both rings will be operating with top-up injections from a full-energy injector. During injection, the electron beam is first delivered to the main injector from a thermionic pre-injec

High-resolution superconducting single-flux quantum comparator for sub-Kelvin temperatures

A design of sub-Kelvin single-flux quantum (SFQ) circuits with reduced power dissipation and additional cooling of shunt resistors has been developed and characterized. The authors demonstrate operation of SFQ comparators with current resolution of 40 nA at 2 GHz sampling rate. Due to improved cooling the electron temperature in shunt resistors of a SFQ comparator is below 50 mK when the bath temp

Mitochondrial DNA sequence evolution and phylogeny of the Atlantic Alcidae, including the extinct great auk (Pinguinus impennis)

The Atlantic auk assemblage includes four extant species, razorbill (Alca torda), dovekie (Alle alle), common murre (Uria aalge), and thick-billed murre (U. lomvia), and one recently extinct species, the flightless great auk (Pinguinus impennis). To determine the phylogenetic relationships among the species, a contiguous 4.2-kb region of the mitochondrial genome from the extant species was amplifi

Manned Mission to Mars: Water as Radiation Shielding During a Solar Particle Event

Det ligger i människans natur att utforska och söka efter det okända. Nu arbetas det hårt för att möta de stora utmaningarna som måste övervinnas för att en bemannad resa till Mars ska bli verklighet. NASA planerar att skicka människor till Mars under 2030-talet och det privata företaget SpaceX har målet att skicka en bemannad farkost till Mars så tidigt som år 2024. Resan till Mars utgör mångfase"Space agencies and privat e companies are working hard to solve the various challenges that need to be overcome to take humans to Mars . The journey to Mars has mult ifaceted risks for the crew, includin g radiation exposure. One risk factor that could jeopar dize t he crew's healt h is the radiation dose from a !arge solar partide event (SPE)

The Säm fold structure : characterization of folding and metamorphism in a part of the eclogite–granulite region, Sveconorwegian orogen

Strukturella och petrologiska studier av komplext veckade mafiskt- och felsiskt varvade sekvenser har genomförts i den paraautoktona delen av Svekonorvegiska provinsen i sydvästra Sverige. Tre deformationsfaser (D1, D2, D3) innefattande minst två veckfaser (F2, F3) och två lineationsfaser (L2, L3) karakteriserar ett flerfasigt veck i migmatiserad och mycket kompetent granatamfibolit. Denna enhet vStructural and petrological studies on complexly folded mafic and felsic layered sequences have been mapped in the parautochthonous basement of the Sveconorwegian Province, Sweden. Three deformation phases (D1, D2, D3)involving at least two fold phases (F2, F3) and two lineation phases (L2, L3) characterize a polyphase fold, which is primarily defined by a migmatized and highly competent garnet am

Han, hon eller Handikappad? En studie kring sexualitet och normalitet hos individer med intellektuell funktionsnedsättning

Denna studie undersöker möjligheterna för individer med intellektuella funktionsnedsättningar att ha ett sexuellt aktivt liv. Med hjälp av en observation, en gruppintervju och sju stycken kvalitativa intervjuer med personal och individer med intellektuella funktionsnedsättningar, har jag sökt svaret på denna fråga. Genom ett teoretiskt ramverk bestående av Queer-, Crip- och Goffmans dramaturgiska This study investigates the opportunities for individuals with intellectual disabilities to have a sexual active life. With the help of an observation, a group interview and seven qualitative interviews with staff and individuals with intellectual disabilities, I have sought the answer to this question. Through a theoretical framework consisting of Queer-, Crip- and Goffman's dramaturgical the

Användbara kravspecifikationer vid upphandling av verksamhetssystem inom kommunal vård och omsorg

Syftet med examensarbetet var att undersöka hur användbarhet beaktas och inkluderas vid köp av verksamhetssystem inom kommunal vård och omsorg. Verksamhetssystem som upplevs som användbara av personalen kan effektivisera det dagliga arbetet samt bespara kommuner tid och pengar. Målet med arbetet var att besvara fyra frågor om användbarhet relaterat till kravspecifikationerna samt slutanvändarna. The purpose of the thesis was to investigate how usability is included when purchasing operational systems within the Swedish municipal health care sector. Systems, which are perceived as usable by the users, may cause the daily tasks to be executed more efficiently and effectively. Consequently, the municipalities can save time and money. The goal of the thesis was to answer four stipulated que

Framtagning av IoT-prototyp med LoRa och GPS

This thesis work has has been done at Sensative in Lund and the goal has been to build a prototype of a product which the company then may build further upon. The product aims to combine IoT with social responsibility by preventing drowning accidents with the data that is generated and sent via the product. Based of an initial description of the product provided by Sensative, the work then was div

Development of protocols for high-efficiency cloning for production of bispecific antibodies and soluble single-chain variable fragments

In the field of molecular biology, the cloning of DNA is a vital process. Through cloning, researchers can design new DNA strands which can be used for a number of applications. One of these applications is the creation of synthetic antibodies for cancer treatments. Alligator Bioscience is developing a high-throughput chain to significantly speed up the process. Traditional cloning techniques rely

Kloning, överuttryck och upprening av växtakvaporinet AtSIP1;1 i Escherichia coli

En ny underfamilj av cellulära vakter i växter Heterologt överuttryck av proteiner innebär att en gen som kodar för ett protein uttrycks i en annan värdorganism som normalt inte har den genen i sin arvsmassa. Inom biokemisk forskning är detta en viktig metod för att kunna studera proteiners struktur och funktion. Tyvärr kan uttrycket av en främmande gen medföra skador på värdorganismens celluläraHeterologous overexpression of proteins signifies that the encoding gene of a protein in one organism is expressed in another host organism that normally does not have that gene in its genome. In basic biochemical research, this is an important method for studying various protein functions such as activity and interactions in biological processes, as well as obtaining sufficient amounts to determi