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A prediction model for the 40-year risk of knee osteoarthritis in adolescent men

OBJECTIVES: To simplify the previously published Nottingham 12-year risk prediction model for knee osteoarthritis (OA) and examine whether it can be used to predict the 40-year risk of knee OA in young men.METHODS: We included 40 118 men aged 18 undergoing military conscription in Sweden 1969-70. Diagnostic OA codes were obtained from the Swedish National Patient Register 1987-2010. The original N

Immune function and blood parasite infections impact stopover ecology in passerine birds

Stopovers play a crucial role for the success of migrating animals and are key to optimal migration theory. Variation in refuelling rates, stopover duration and departure decisions among individuals has been related to several external factors. The physiological mechanisms shaping stopover ecology are, however, less well understood. Here, we explore how immune function and blood parasite infection

Urban Nature - Connecting Cities, Sustainability and Innovation : Course Guide

How can we work with nature to design and build our cities? This course explores urban nature and nature-based solutions in cities in Europe and around the world. We connect together the key themes of cities, nature, sustainability and innovation. We discuss how to assess what nature-based solutions can achieve in cities. We examine how innovation is taking place in cities in relation to nature. A

Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty : a double-blind, randomised controlled trial

BACKGROUND: The risk of venous thromboembolism is high after total hip arthroplasty and could persist after hospital discharge. Our aim was to compare the use of rivaroxaban for extended thromboprophylaxis with short-term thromboprophylaxis with enoxaparin.METHODS: 2509 patients scheduled to undergo elective total hip arthroplasty were randomly assigned, stratified according to centre, with a comp

Baseline QRS Area and Reduction in QRS Area Are Associated with Lower Mortality and Risk of Heart Failure Hospitalization after Cardiac Resynchronization Therapy

Introduction: Cardiac resynchronization therapy (CRT) is an established treatment for heart failure in selected patients. However, current guideline indications do not accurately predict individual prognosis with CRT, and up to 30% are nonresponders. Previous studies have shown that QRS area reduction following CRT is associated with improved survival. This study evaluates the incremental value of

Computational and Experimental Inverse Problem Approach for Determination of Time Dependency of Heat Flux in Metal Cutting

This study develops the method for solution of inverse heat conduction problem applied to metal cutting. The proposed method operates with a selection procedure involving iterative solutions of heat forward problem. In such formulation, it allows avoiding difficulties associated with ill-posed inverse problems inherent to conventional formulations. Inverse heat problem was transformed into constra

Introducing the Brassica Information Portal : Towards integrating genotypic and phenotypic Brassica crop data [version 2; peer review: 3 approved]

The Brassica Information Portal (BIP) is a centralised repository for brassica phenotypic data. The site hosts trait data associated with brassica research and breeding experiments conducted on brassica crops, that are used as oilseeds, vegetables, livestock forage and fodder and for biofuels. A key feature is the explicit management of meta-data describing the provenance and relationships between

A theory-based approach to evaluations intended to inform transitions toward sustainability

There is an urgent need for radical transformations of unsustainable socio-technical systems, such as food, mobility, and housing. These transformations will not take place without new policies and research. In order to achieve these transitions, learning must be a central feature based on thorough evaluations of the actions taken. Evaluations have been conducted and studied for decades, but tradi

Patient consultations during SARS-CoV-2 pandemic : a mixed-method cross-sectional study in 16 European countries

INTRODUCTION: Remote consultations help reduce contact between people and prevent cross-contamination. Little is known about the changes in consultation in European rural primary care during the SARS-CoV-2 (COVID-19) pandemic. The purpose of this mixed-methods cross-sectional study was to find out more about the effects of the pandemic on changes in patient consultations in European rural primary

Thrombomodulin (THBD) gene variants and thrombotic risk in a population-based cohort study

Background: The protein C anticoagulant system plays a key role in maintaining the hemostatic balance. Although several studies have identified thrombomodulin gene (THBD) variants among venous thromboembolism (VTE) patients, the role of THBD in relation to VTE in humans remains to be clarified. Objectives: This study aimed to determine the thrombotic risk of rare and common THBD variants in a larg

Matrix Approach to Land Carbon Cycle Modeling

Land ecosystems contribute to climate change mitigation by taking up approximately 30% of anthropogenically emitted carbon. However, estimates of the amount and distribution of carbon uptake across the world's ecosystems or biomes display great uncertainty. The latter hinders a full understanding of the mechanisms and drivers of land carbon uptake, and predictions of the future fate of the land ca

The Impact of Crowdfunding and its Ability to facilitate the Liability of Newness: A Case Study on New Ventures within the Product Design Industry

Crowdfunding is often considered as a financial source to close the early stage financial gap of new ventures. However, there is little research on its impact regarding other liabilities new ventures face. The aim of this study is to find evidence on how crowdfunding can provide new ventures with additional value apart from financial resources. For this purpose, the concept of liability of newness

Känslomjukisen – Vila, känslor, kommunikation och lek

The goal of this Project was to find solutions to stress related Health issues by analyzing the concept of rest and how to incorporate new ways of resting into our everyday lives. Research through literature, seminars and articles on the Internet led to the realization that emotional rest is of great importance to mental and physical health. Since emotional rest is achieved by emotional developm

An Evaluation of the Impacts of Bolsa Família on Schooling

Conditional cash transfer programs have been proven effective when aiming to decrease poverty and increase school enrollment among poor. The Brazilian conditional cash transfer program Bolsa Família is the largest program in the developing world and affect 13 million families in their everyday life. One of the long-term aims of Bolsa Família is to increase school enrollment in Brazil, which also i

Fly Tephritis conura´s adaption to new host plant

The genes that enable using a new host plant Insects and their host plants constitute a large share of biodiversity. This suggests that their interactions promote adaptation, leading to diversification. The development of sequencing techniques has now enabled us to address what changes in the genome enable such adaptation. In this project, I investigated the genomic basis of fly Tephritis conura

Rökpartiklars storleks beroende av syrehalt

Particle size can be an important variable to know in many different areas, be it smoke simulations, toxicity of materials or tests of face masks. Fires in a reduced oxygen environment can occur for ventilation-controlled fires or in areas with artificially lowered oxygen levels. The effects of lower concentrations of oxygen on heat release rate, smoke production etc. has been studied, but any eff

The Role of Concept Stores: Consumer Perception of the Intended Brand Image

Title: The Role of Concept Stores: Consumer Perceptions of the Intended Brand Image Seminar date: 2024-05-30 Course: BUSN39, Degree Project in Global Marketing, Business Administration: Master Level Authors: Petra Ohlson & Emma Stenkil Supervisor: Ulf Johansson Research question: Why are fashion manufacturing brands opening concept stores? How does consumers' perception of the concept stor

A Joint Sensing Framework for Real-time Mobile Camera Localization

In this paper, a joint perception framework combining fixed and mobile cameras is proposed, which can achieve accurate real-time positioning of the mobile camera in a unified coordinate system. The system integrates VGGT for high-precision pose estimation and combines it with MASt3r-SLAM for robust real-time tracking. Alignment between different coordinate systems is achieved through rotation matr

Fragmentomic analysis of circulating tumor DNA-targeted cancer panels

BACKGROUND: The isolation of cell-free DNA (cfDNA) from the bloodstream can be used to detect and analyze somatic alterations in circulating tumor DNA (ctDNA), and multiple cfDNA-targeted sequencing panels are now commercially available for Food and Drug Administration (FDA)-approved biomarker indications to guide treatment. More recently, cfDNA fragmentation patterns have emerged as a tool to inf