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The murine embryonal stem (ES) cell virus (MESV) can express transgenes from the long terminal repeat (LTR) promoter/enhancer in undifferentiated ES cells, but expression is turned off upon differentiation to embryoid bodies (EBs) and hematopoietic cells in vitro. We examined whether a human immunodeficiency virus type 1-based lentivirus vector pseudotyped with the vesicular stomatitis virus G pro
AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as
End-use efficiency, demand response and coupling of different energy vectors are important aspects of future renewable energy systems. Growth in the number of data centres is leading to an increase in electricity demand and the emergence of a new electricity-intensive industry. Studies on data centres and energy use have so far focused mainly on energy efficiency. This paper contributes with an as
PurposeIncumbent retail organisations need to develop new capabilities to adapt with the increasingly competitive retail landscape. Despite the growing relevance of innovation in retail practice, the strategic management of innovation in retailing is still vastly under-researched. This explorative study thus aims to investigate how incumbent retail firms can organise for innovation from an organis
Molecular blood biomarkers are lacking for high-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN). To histologically distinguish between neuroendocrine carcinoma (NEC), neuroendocrine tumors G3 (NET G3), adenocarcinoma and MINEN is often challenging. The mRNA-based NETest has diagnostic, prognostic and predictive value in neuroendocrine tumors G1-2 but has not been studied in
Generalist parasites experience selective pressures from the various host species they infect. However, it is unclear if parasite transmission among host species precludes the establishment of host-specific adaptations and population genetic structure. We assessed the population genetic structure of the vector-transmitted avian haemosporidian parasite Haemoproteus majoris (lineage WW2; n = 34 infe
Evolutionary changes in populations of microbes, such as microalgae, cannot be traced using conventional metabarcoding loci as they lack intraspecific resolution. Consequently, selection and competition processes among strains of the same species cannot be resolved without elaborate isolation, culturing, and genotyping efforts. Bamboozle, a new bioinformatic tool introduced here, scans the entire
Many companies today are transforming their development process by leaving an old-fashioned one, like the waterfall model, behind and instead aiming for a modern process like Scrum that can keep up with today’s rapid market changes and reduce time to market lag. These companies are often aiming to become more agile and with this comes a need for short release cycles in order to get fast feedback a
The modern human being is exposed to different kinds of light during a normal day, both natural light and adjusted lighting. The idea that light affects us is uncontested, and so affecting the light in turn becomes a question of well-being. It is often thought that abundant and strong lighting is good lighting, but this is far from always accurate. Moreover, the light from a regular lightbulb is i
The purpose of this study is to explore the opportunities and challenges for self-employed artists who use social media for their business. The research is focused on painters and illustrators who have digitalised and commercialised their own artwork. The method follows a qualitative research framework with a comparative design of multiple cases on the level of individual artists. Seven artists fr
How should we deal with city planning in a world that is rapidly turning urban, without destroying valuable nature assets along the way? The last decades are proof that the system we are using today is not up to the challenge. Therefore this thesis is showing a new approach to how comprehensive city planning can grow from nature based values and a deeper understanding of a city’s foundation. Toda
Purpose – Increasingly, last mile logistics is driven by customer-oriented strategies that requires better understanding of customers’ perceptions. This thesis views last-mile delivery as a service and aims to examine the relation of logistics service quality and other constructs used in service management literature to measure customers’ perception. Built on the operational definition of perceive
Abstract The self-driving car (SDC) is about to exit fantasy and enter reality. SDCs are expected to be available for purchase in just a few years, and the new technologies that enable autonomous driving hold much promise, regarding safety, environmental impact, increased mobility and higher comfortability. However, there are worrying prospects, too. Some experts worry that the autonomous car
This project focuses on how a household in Malmö can manage a crisis situation with no electricity, water, heat and communication for 72 hours. This is due to the recommendation that we can take care of ourselves for 3 days in case of a crisis. This spring residents of Cape Town have been living with water restrictions of 50 litres per person per day. This can be compared to the 160 litres per per
This thesis is a combined conceptual study and preliminary design of two study options for a future tramway line between Trädgårdsgatan and Hälsovägen in Helsingborg. This line is of great interest since it’s centrally located and regarded as a problematic stretch of narrow streets, heavy traffic and steep gradients. In addition, a local tramway line in Helsingborg is regarded as a priority projec
Historiskt sett har människor byggt sina hus med de material som den omgivande naturen gav. Både vass och lera är två sådana material som förekommer naturligt. Det som bl.a. skiljer dessa material åt är de processer som krävs för att de ska kunna användas som taktäckningsmaterial. Vassen skördas och torkas medan leran bearbetas och bränns för att slutligen bli en användbar produkt. I tidigare svenHistorically, people built their houses with the materials that the surrounding nature gave. Reeds and clay are two such materials occurring naturally. A difference between these materials is the processes required for them to be used as roofing material. Reed is harvested and then dried while the clay is processed and fired to finally become the useful product. In earlier Swedish history roofs we
En proglacial miljö är en integrerad del av ett glacialt landskap, där smältvattensavlagrade landformer är vanligt förekommande. Deras utseende är beroende av ett antal olika faktorer, så som processer aktiva under transport och deposition samt ursprungsmaterialets karaktär. Denna artikel syftar till att undersöka två terrestra smältvattens-successioner från de terminala delarna av glaciären MyrdaProglacial environments are an integrated part of the glacier landscape, housing a variety of landforms fed by glacier meltwater. Their appearance is dependent on a number of factors, such as the variability of source material and processes active during the transportation and deposition. The present work aims to investigate two such terrestrial outwash successions from the terminus region of the
User Experience is a concept that recently has gained a lot of interest in the high-tech consumer products industry. While technology development has converged and is starting to become a commodity and, as markets mature and loyal customers become more important, User Experience has emerged as a way to gain a competitive advantage. By studying literature, cases and articles, as well as interviewin
Arbetsgivarens rehabiliteringsansvar innebär, i samband med att en arbetstagare får nedsatt arbetsförmåga till följd av sjukdom, en skyldighet att utreda arbetsanpassnings- och rehabiliteringsmöjligheterna för att möjliggöra återgång i arbete. Rehabiliteringsansvaret regleras främst inom lagen om (1982:80) anställningsskydd, arbetsmiljölagen (1977:1160), socialförsäkringsbalken (2010:110) och kompThe employer's responsibility to rehabilitate is, in connection with an employee's reduced ability to work as a result of illness, an obligation to investigate work adaptation and rehabilitation possibilities to enable a return to work. The responsibility for rehabilitation is mainly regulated within the Employment Protection Act (LAS), the work environment act (AML), the social insurance
Forskningsfråga: Skiljer sig kapitalstrukturen mellan familjeföretag och icke-familjeföretag? Syfte: Studiens syfte är att undersöka om det finns en skillnad i kapitalstruktur mellan familjeföretag och icke-familjeföretag noterade på börsen i Sverige. Utöver det undersöks hur företagsspecifika variabler, som exempelvis storlek, bransch och lönsamhet, påverkar företagens skuldsättningsgrad. MetodResearch Question: Does the capital structure differ between family-owned and non-family-owned businesses? Purpose: The purpose of this study is to investigate whether there is a difference in capital structure between family-owned and non-family-owned companies listed on the Swedish stock market. Additionally, the study examines how firm-specific variables, such as size, industry, and profitabil
