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Associations of dietary fiber with glucose metabolism in nondiabetic relatives of subjects with type 2 diabetes - The Botnia Dietary Study

OBJECTIVE - To study cross-sectional associations of dietary fiber intake with insulin resistance, insulin secretion, and glucose tolerance in a population at high risk for type 2 diabetes. RESEARCH DESIGN AND METHODS - The subjects consisted of 248 male and 304 female adult nondiabetic relatives of patients with type 2 diabetes. Dietary intake was measured by means of two 3-day food records. Asso

A 2-year follow-up study of anxiety and depression in women referred for colposcopy after an abnormal cervical smear.

OBJECTIVES: The aim of this study was to determine if there were any long-lasting elevated anxiety levels in women attending colposcopy after an abnormal cervical smear. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynaecology, Malmö University Hospital, Sweden. POPULATION: One hundred consecutive women were invited to participate when referred for colposcopy. METHODS: Women in

Integrating needs assessment within next generation e-learning systems: lessons learnt from a case study

In this paper we outline a method for systematically addressing needs assessment (QUALISEM-PEOPLE), alongside a case study of its use within a medium sized, German company. The method was designed in order to provide guidance in analysing skill and role competences, particularly when e-learning systems are being considered for training purposes. The method proved to be successful within the compan

Repositionable percutaneous aortic valve implantation with the LOTUS valve : 30-day and 1-year outcomes in 250 highrisk surgical patients

Aims: The REPRISE IIE trial aimed to evaluate outcomes following transcatheter aortic valve implantation of the fully repositionable and retrievable LOTUS valve with a unique seal designed to minimise paravalvular leak (PVL). Methods and results: This prospective, multicentre study enrolled 250 patients with severe aortic stenosis considered high-risk for surgery by a multidisciplinary Heart Team.

Framing the Basic Income : An Experimental Study of How Arguments and Metaphors Influence Individuals' Opinion Formation

Using an experimental design, this paper tackles the question of the framing impact of metaphors by focusing on the opportunity to implement a basic income (BI) system in a given polity. We take advantage of the preliminary stage of the BI debate in Belgium to study the influence of discursive strategies on the opinion formation process of individuals, since carefully choosing the arguments employ

Genetic testing and surveillance guidelines in hereditary pheochromocytoma and paraganglioma

Pheochromocytoma and paraganglioma (PPGL) are rare tumours and at least 30% are part of hereditary syndromes. Approximately 20% of hereditary PPGL are caused by pathogenic germ line variants in genes of the succinate dehydrogenase complex (SDHx), TMEM127 or MAX. Herein we present guidelines regarding genetic testing of family members and their surveillance based on a thorough literature review. Al

Hyperglycemia in Extremely Preterm Infants—Insulin Treatment, Mortality and Nutrient Intakes

Objective: To explore the prevalence of hyperglycemia and the associations between nutritional intakes, hyperglycemia, insulin treatment, and mortality in extremely preterm infants. Study design: Prospectively collected data from the Extremely Preterm Infants in Sweden Study (EXPRESS) was used in this study and included 580 infants born <27 gestational weeks during 2004-2007. Available glucose mea

A large-scale, high-efficiency and low-cost platform for structural genomics studies

A large-scale, high-efficiency and low-cost platform based on a Beckman Coulter Biomek FX and custom-made automation systems for structural genomics has been set up at Peking University, Beijing, People's Republic of China. This platform has the capacity to process up to 2000 genes per year for structural and functional analyses. Bacillus subtilis, a model organism for Gram-positive bacteria, and

Head midline position for preventing the occurrence or extension of germinal matrix-intraventricular hemorrhage in preterm infants

Background: Preterm birth is known to constitute the major risk factor for development of germinal matrix-intraventricular hemorrhage (GM-IVH). Head position may affect cerebral hemodynamics and thus may be involved indirectly in development of GM-IVH. Turning the head toward one side may functionally occlude jugular venous drainage on the ipsilateral side while increasing intracranial pressure an

Diversity and functions of intestinal mononuclear phagocytes

The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mÏ †) that collectively play an essential role in mucosal homeostasis, infection and inflammation. In the current review we discuss the function of intestinal cDC and monocyte-derived MNP, highlighting how these

Mathematical modeling of the protein corona : Implications for nanoparticulate delivery systems

This article discusses the role of the protein corona in delivery systems with tagged nanoparticles and how knowledge of the protein corona can help in optimizing delivery. The basic question is whether and how the binding of proteins and other biomolecules at the nanoparticle surface interfere with the interaction between a tag and its receptor. This is an interesting problem in many respects, bu

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017 : a systematic analysis for the Global Burden of Disease Study 2017

BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be liv

Design and synthesis of photoactive iron n-heterocyclic carbene complexes

The use of iron in photoactive metal complexes has been investigated for decades. In this respect, the charge transfer (CT) states are of particular interest, since they are usually responsible for the photofunctionality of such compounds. However, only recently breakthroughs have been made in extending CT excited state lifetimes that are notoriously short-lived in classical polypyridine iron coor

Event-based distributed robust synchronization control for multiple Euler-Lagrange systems without relative velocity measurements

This paper focuses on the event-based distributed robust leaderless synchronization control for multiple Euler-Lagrange systems with directed communication topology that contains a directed spanning tree. Update frequency of the system is reduced by taking advantages of the event-triggered approach, which can help extend the service life of the controller. Robust control theory is employed to guar

A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease

AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as

Urban Nature - Connecting Cities, Sustainability and Innovation : Course Guide

How can we work with nature to design and build our cities? This course explores urban nature and nature-based solutions in cities in Europe and around the world. We connect together the key themes of cities, nature, sustainability and innovation. We discuss how to assess what nature-based solutions can achieve in cities. We examine how innovation is taking place in cities in relation to nature. A

Survival after operations for ischaemic bowel disease

Objective: To find out what factors influence the outcome of operations for ischaemic bowel disease. Design: Retrospective study. Setting: University hospital, Sweden. Main outcome measures: Morbidity and mortality. Subjects: 74 patients, mean age 75 years (range 40-98), operated on for acute bowel ischaemia between 1987 and 1996. Results: A total of 75 emergency operations were done, including 42

The Impact of Crowdfunding and its Ability to facilitate the Liability of Newness: A Case Study on New Ventures within the Product Design Industry

Crowdfunding is often considered as a financial source to close the early stage financial gap of new ventures. However, there is little research on its impact regarding other liabilities new ventures face. The aim of this study is to find evidence on how crowdfunding can provide new ventures with additional value apart from financial resources. For this purpose, the concept of liability of newness

Känslomjukisen – Vila, känslor, kommunikation och lek

The goal of this Project was to find solutions to stress related Health issues by analyzing the concept of rest and how to incorporate new ways of resting into our everyday lives. Research through literature, seminars and articles on the Internet led to the realization that emotional rest is of great importance to mental and physical health. Since emotional rest is achieved by emotional developm

Exploring LSP’s value proposition process in E-commerce supply chain

Service is a process that doing something for someone that is valued. This thesis explores LSPs’ value proposition process in e-commerce supply chain. In addition, try to investigate in-depth about what would be importance of service-dominant logic in the context, and how can it propose and co-create value in the e-commerce supply chain management. This study provides the chance for the author to