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Spårväg i Helsingborg - En idéstudie och förprojektering av två spårvägslinjer mellan Trädgårdsgatan och Hälsovägen

This thesis is a combined conceptual study and preliminary design of two study options for a future tramway line between Trädgårdsgatan and Hälsovägen in Helsingborg. This line is of great interest since it’s centrally located and regarded as a problematic stretch of narrow streets, heavy traffic and steep gradients. In addition, a local tramway line in Helsingborg is regarded as a priority projec

Analysis of vitamin D and its metabolites in biological samples – Part I : Optimization and comparison of UHPSFC-MS/MS and UHPLC-MS/MS methods

Fat-soluble vitamin D is an essential bioactive compound important for human health. Insufficient vitamin D levels can result not only in bone disease but also in other disorders, such as cancer, metabolic disorders, and diseases related to poor immune function. The current methods commonly used for vitamin D analysis are often applied to determine the levels of the most abundant metabolite in pla

Who changes what, when and where? Elaborating postponement when integrating hardware and software objects in global supply chains

Purpose: The postponement principle concerns defining when and where value is added, usually referring to hardware components for physical products. However, in modern supply chains, software’s importance is increasing, impacting the timing and location of value-adding operations. Lacking insights into software-driven implications for postponement, we aim at elaborating on the postponement princip

Disease burden and unmet need for acute allergic reactions – A patient perspective

BACKGROUND: Acute allergic reactions (AARs) occur shortly after exposure to an allergen, and the severity is on a continuum. Systemic corticosteroids (CS) are mainstay treatment of moderate to severe AARs, whereas those at risk of the most severe AARs (ie, anaphylaxis) are also recommended prescription of epinephrine autoinjectors. There is limited research on the impact of AARs not fulfilling the

Phenotypic plasticity in floral scent in response to nutrient, but not water, availability in the perennial plant Arabis alpina

Floral scent is an important mediator of plant–pollinator interactions. Multiple recent studies report ample intraspecific scent variation among populations and individuals. Yet, few studies have eastimated effects of phenotypic plasticity on floral scent in response to differing environmental factors. In this study, we investigated the effects of nutrient and water availability on floral scent in

Stepup2013 birgitta sophie

Grant applications BIRGITTA LARSSON OCH SOPHIE HYDÉN PICASSO, FORSKNINGSSERVICE Research Services at LU •  Started as support for EU projects in the mid-90s •  Today: work with research funding, research communication, doctoral education •  Mainly a service organisation, centrally located to serve all faculties •  Prioritised research grants – Nationally: university-wide applications and research

https://www.wings.lu.se/sites/www.wings.lu.se/files/stepup2013_birgitta_sophie.pdf - 2026-05-03

Associations of Prenatal Mercury Exposure and PUFA with Telomere Length and mtDNA Copy Number in 7-Year-Old Children in the Seychelles Child Development Nutrition Cohort 2

BACKGROUND: Telomere length (TL) and mitochondrial DNA copy number (mtDNAcn) variations are linked to age-related diseases and are associated with environmental exposure and nutritional status. Limited data, however, exist on the associations with mercury exposure, particularly early in life.OBJECTIVE: We examined the association between prenatal mercury (Hg) exposure and TL and mtDNAcn in 1,145 S

Femoral Neck Hounsfield Units as an Adjunct for Bone Mineral Density After Combat-Related Lower Extremity Amputation

OBJECTIVES: To correlate femoral neck Hounsfield units (HUs) measured on a computed tomography (CT) scan to dual-energy x-ray absorptiometry (DEXA) T-scores allowing evaluation of bone mineral density (BMD) over time after lower extremity trauma-related amputation.DESIGN: Retrospective cohort study.SETTING: United States military trauma referral center.PATIENTS: Military combat-related lower extre

Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes

Introduction Despite the improvements in diabetes management by continuous glucose monitoring (CGM) it is difficult to capture the complexity of CGM data in one metric. We aimed to develop a clinically relevant multidimensional scoring model with the capacity to identify the most alarming CGM episodes and/or patients from a large cohort. Research design and methods Retrospective CGM data from 2017

Performance of five cardiotocography classification templates in labor : a cohort study

Objective: New guidelines for the interpretation of cardiotocography (CTG) have been presented by FIGO in 2015 (FIGO-15) and by NICE in 2017 (NICE-17) and 2022 (NICE-22) In Sweden, a previous template from 2009 (SWE-09) was replaced in 2017 (SWE-17). The objective of the study was to compare these five different templates for CTG classification regarding sensitivity, specificity, positive and nega

Plasma VEGF-D and sFLT-1 are potential biomarkers of hemodynamics and congestion in heart failure and following heart transplantation

BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva

Digital learning resource use among Swedish medical students : insights from a nationwide survey

BACKGROUND: Medical students navigate a complex landscape of digital tools with potential to enhance learning. The main objectives of the current study were to investigate which digital resources are being used, which background factors are associated with utilization, perceived advantages and disadvantages of different digital resources, and explore future directions.METHODS: Cross-sectional, nat

TREM2 risk variants and associated endophenotypes in alzheimer’s disease

Background: Rare variants of the triggering receptor expressed on myeloid cell 2 (TREM2) gene are strong risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown what the effect of TREM2 variants is on the AD phenotype. Methods: Here we studied a full range of clinical and biomarker measures in a large cohort of TREM2 variant carr

Extra-uterine placental transfusion and intact-cord stabilisation of infants in caesarean sections : an intervention development and pilot-study (INTACT-1)

Background: Keeping the umbilical cord intact the first minutes after delivery is beneficial for both term and preterm infants. However, this may be challenging in caesarean sections (CS) due to lack of mobile resuscitation equipment, maintenance of sterility or concern for excessive maternal blood loss. The objective of this study was to develop and pilot-test extra-uterine placental transfusion

Evaluation of Software-Optimized Protocols for Acoustic Noise Reduction During Brain MRI at 7 Tesla

Background: MR-generated acoustic noise may be particularly concerning at 7-Tesla (T) systems. Noise levels can be reduced by altering gradient output using software optimization. However, such alterations might influence image quality or prolong scan times, and these optimizations have not been well characterized. Purpose: To evaluate image quality, sound pressure levels (SPLs), and perceived noi

Brandrisker vid lägre syrehalter – Experiment i konkalorimetern

This report has been conducted to examine the advantages and disadvantages of using an open system for experiments in the cone calorimeter with a vitiated air enclosure at low oxygen levels. Eight different experimental set-ups were conducted in which two were designed according to ISO 5660, i.e. the cone calorimeter in its standard configuration. In the other experimental set-ups, a chamber which

Climate change impact on water balance and export of dissolved organic carbon : a sub-catchment modelling approach

Att förutsäga framtiden – modellering som ett verktyg för att förutsäga vattenkvantitet och vattenkvalitet Inom 100 år så kommer klimatet förändrats avsevärt om utsläpp av växthusgaser fortsätter i samma takt som idag. Detta kommer påverka temperatur, nederbörd vilka i sin tur påverkar flödet av vatten i Sverige. Ett avrinningsområde består av olika jordtyper, vegetation och topografi, vilka allClimate change will alter the hydrological cycle in the 21st century with implications for the water balance and water quality. As characteristics of the landscape may vary significantly between nearby locations, hydrological models need to be able to delineate responses attributed to specific landscape characteristics, to estimate their responses to altered climatic drivers. Small streams are the

Ute och ränner – Elektronisk övervakning av unga lagöverträdare

Denna uppsats syftar till att undersöka vilka effekter ett införande av fotboja som ungdomspåföljd skulle innebära för de unga som i så fall skulle komma i fråga för påföljden. Utgångspunkt tas i det förslag på införande av fotboja för unga som återfinns i SOU 2012:34 Nya påföljder, där påföljden kallas för ungdomsövervakning. Inledningsvis tecknas en översiktlig bild av det rättspolitiska dagsläThe aim of this thesis is to examine the potential effects on youths of an introduction of electronic tagging into the Swedish penal system for juveniles. The proposition of such electronic tagging, presented in SOU 2012:34 Nya påföljder (“New sanctions”) by the name ungdomsövervakning (“youth monitoring”), acts as a starting point for the investigation of the expected effects on youths. First,

Only for the rich? Low-carbon energy transition in the Vauban (Freiburg, Germany)

This thesis examines a local low-carbon energy transition in an urban context with regard to energy justice. It takes the Vauban district in Freiburg (Germany) as a case study which has been described as a successful case of energy transition and a model for sustainable urban development. From a theoretical point of view, energy justice encompasses a fair distribution of costs and benefits of an e