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Background. Prostate specific antigen (PSA) is a zymogen of a 33‐kilodalton (kD) serine proteinase with extensive similarity to glandular kallikreins. The mechanism responsible for converting the zymogen into active proteinase has not been defined, but active PSA may be irreversibly inactivated in vitro by two of the major proteinase inhibitors in blood: alpha1‐antichymotrypsin and alpha2‐macroglo
The objective of the present study was to investigate the effect of polymorphism on in vitro-in vivo properties of carbamazepine (CBZ). For this purpose, three different polymorphs and a dihydrate of CBZ were obtained and the conventional tablets of these crystalline forms at the dose of 200 mg were prepared. The polymorphs were examined by the IR and DSC analysis. The tablets were investigated by
OBJECTIVE - To analyze the effect of antibodies to glutamic acid decarboxylase (GAD65Ab) and islet cells (ICA512Ab) on glycemic control early in IDDM. RESEARCH DESIGN AND METHODS - GAD65Ab and ICA512Ab were measured twice in 35 patients (10 male, 25 female; age 1040 years) initially within 2 years of diagnosis and again 1 year later. The glycosylated hemoglobin was measured one to four times each
Objectives: To identify ultrasound features of papillations or of the cyst wall that can discriminate between benign and malignant unilocular-solid cysts with papillations but no other solid components. Methods: From the International Ovarian Tumor Analysis (IOTA) database derived from seven ultrasound centers, we identified patients with an adnexal lesion described at ultrasonography as unilocula
Environmental protection has become high in the policy agenda of East Asian countries by the end of the last century due to both internal and external stimuli. One of the main environmental issues is the management of solid waste. The concept of circular economy which encourages reduce, reuse, and recycling, i.e. 3Rs, together with the principle of Extended Producer Responsibility (EPR) has been p
Objective: To examine neuropsychological performance as a possible predictor of course and outcome in first-episode psychotic (FEP) patients. Method: A group of consecutive FEP patients (n = 120) tested with Wechsler Adult Intelligence Scales-Revised (WAIS-R) at baseline was compared with a healthy group (n = 30) matched for age, education and gender. Relationship between WAIS-R and both Brief Psy
Background: Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution. Methods: We have estimated exposure to Environmental Tobacco Smoke (ETS) and to air pollution in never smokers and ex-smokers in
Objective:To investigate the prevalence and the secular trends of obesity in a rural Swedish community with emphasis on the association with socioeconomic status and lifestyle.Design:The Skaraborg Project cross-sectional population surveys were conducted in Vara, a rural community in the southwest of Sweden, every fifth year between 1977 and 2002.Subjects:A total of 3365 residents (1634 men and 17
Under lång tid fanns inte någon specialreglering i svensk rätt gällande skadeståndsansvaret vid dammhaverier. I juli 1997 infördes en lag som förändrade detta och pekade ut ansvarssubjekt med ett rent strikt ansvar. Den underhållsskyldige för en dammanläggning innehar ett strikt ansvar för de skador som uppstår nedströms till följd av ett dammhaveri enligt 11 kap. 18 § miljöbalken. UnderhållsskylFor a long time, there was no regulation of the indemnity liability for dam failures in Sweden. In July 1997 a new law brought a change to this and clarified which liable entity was strictly liable for damages. The entity responsible for maintaining the dam bears a strict liability for all damages arising downstream as a consequence of a dam failure according to chapter 11 paragraph 18 in the Swe
This essay concerns the complementation of the English emotive verbs like, love, hate and prefer. In English, gerund-participial and infinitival complements often receive semi-synonymous semantic interpretations when complementing emotive verbs. All the while, both complement types supposedly convey separate semantic interpretations, resulting in that they commonly appear in contexts expressing ha
Studien ämnade att undersöka hur väl personlighet respektive könsidentifiering, var för sig respektive tillsammans, kan predicera ideologisk orientering. För att undersöka detta användes personlighetstestet HEXACO och könsidentifieringstestet BSRI. Syftet med uppsatsen var att öka väljarförståelsen. Studien utgick ifrån ett bekvämlighetsurval (N=272), med 171 kvinnor och 101 män. Samtliga var svenThis aim of this thesis was to examine how well personality and gender-identification, by themselves and combined, were able to predict ideological orientation. This through the personality test HEXACO and gender-identification test BSRI. The purpose of the study was to help improve the understanding of Swedish voters. The sample was a convenience sample (N=272), with 171 women and 101 men, all Sw
OBJECTIVE-Many genetic variants have been associated with glucose homeostasis and type 2 diabetes in genome-wide association studies. Zinc is an essential micronutrient that is important for beta-cell function and glucose homeostasis. We tested the hypothesis that zinc intake could influence the glucose-raising effect of specific variants. RESEARCH DESIGN AND METHODS-We conducted a 14-cohort meta-
This report presents the results from a study of 90 km/h rural roads, where the effects of narrow vs. wide lanes on deterioration, safety, winter maintenance etc have been studied. Empirical studies have been performed of lateral positioning and speed on 16 road objects that vary with regards to lane width (3.25m respectively 3.75m) and presence of guardrail (with or without), other parameters hav
OBJECTIVE: Endoleaks and endotension are critically important complications of some endovascular aortic aneurysm repairs (EVARs). For the resolution of controversial issues and the determination of areas of uncertainty relating to these complications, a conference of 27 interested leaders was held on November 20, 2000. METHODS: These 27 participants (21 vascular surgeons, five interventional radio
Wet room - demands and rules This paper explains how the legislative system is built concerning wet rooms within the construction industry. Legislation is developed by all involved authorities. The state has created laws and regulations through parliament and government. These laws are used as a foundation for Boverket, who has produced BBR, which specifies the minimum requirements for the propert
Objective: The aim of the present study was to investigate the perceived anxiety, depression, sleeping habits, and participation in social activities in relation to psychotropic drug use among elderly in assisted-living facilities and to identify factors of importance for the use of these drugs. Method: The study had a cross-sectional design and included 93 residents living in old-age homes or in
Objective Hand Mobility in Scleroderma (HAMIS) is a new hand function test developed for adults who have systemic sclerosis. HAMIS consists of 9 items designed to measure all movements assessed in an ordinary range of motion (ROM)-measured hand test. The aim of this study was to examine the reliability of the test. Methods Two observers (one occupational therapist and one physiotherapist) perform
The thesis focuses on the numerical simulation of the flow field in gas turbine burners. Due to tougher and tougher requirements on low levels of emission of pollutants there is a need for new combustion technologies. In gas turbines one method to attain low pollutant levels is the use of lean premixed combustion. However, in lean combustion, problems related to the flame stability can arise. Swi
Quantitative RT-PCR (QRT-PCR) enables the sensitive and specific detection of mRNA with a small copy number. We used the QRT-PCR method and dual-label analysis of amplification products for the detection of prostate-specific antigen (PSA) mRNA. The QRT-PCR assay employed a PSA-like internal standard (IS) mRNA, which was used to quantify the PSA mRNA copies and to control the variations during the
