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Objectives. The aim was to demonstrate a reliable ex vivo method to test the function of the whole heart. Design. Pigs of varying sizes (44–80 kg) were exposed to dose response of adrenaline. Blood pressures and cardiac output were measured. The explanted hearts were tested in a novel ex vivo system to see if we could replicate the in vivo values at maximal adrenaline stimulation. The perfusion so

Centrifugal compressors are widely used in turbocharged powertrains for Heavy-Duty applications. The volute of the centrifugal compressors is generally of the overhung type. The design of volutes is often neglected, and the shape of the volute is dictated by the packaging requirements of the engine. However, with the advent of Hydrogen-based propulsion systems, the efficiency of all the components

Recent Advances: Various studies have suggested that mitochondrial DNA copy number (mtDNA-CN), a surrogate biomarker of mitochondrial dysfunction, is an easily quantifiable biomarker for chronic diseases, including diabetes and cancer. However, current knowledge is limited, and the results are controversial. This has been attributed mainly to methodology and study design.Critical Issues: The incid

The most important moment in product development is when demands and specifications are decided for the product that is being planned. The specification defines the goal for the product development process. It is a very important steering opportunity for the continuing work and for environmentally driven demands that are to be addressed in the product development phase. The designers are said to h

Peripheral artery disease affects >200 million people worldwide and is associated with significant limb and cardiovascular morbidity and mortality. Limb revascularization is recommended to improve function and quality of life for symptomatic patients with peripheral artery disease with intermittent claudication who have not responded to medical treatment. For patients with critical limb ischemia,

Media, technology and globalization are the key words in academic contemporary consumer and cultural research going on today. From these ideas, many different research directions could diverge. This thesis explores the listening habits of female, native Finnish and English speakers living in Sweden who are within the age groups of 20’s to 40’s. Focusing on media, technology, and mobile world citiz

Previous research on A/B testing and continuous experimentation has mostly focused on large-scale settings with company-external customers. However, work efficiency and satisfaction for company coworkers may be highly related to internal tools and their fit-for-use. In this study, we therefore explore A/B testing for online services exclusively used by company co-workers. We A/B tested two version

Purpose – Competence development is a prerequisite for successfully meeting existing and future challenges in the retail sector. However, current human resource development practices are often limited in their scope and offerings. This study sets out to investigate and bring to light informal learning among retail professionals.Design/methodology/approach – This research consists of two explorator

Natural flood management is emerging as a viable way to leverage ecological services to manage flooding. Stakeholders are progressively positioning natural flood management at the scale of river catchments to encourage a move beyond localised and opportunistic actions towards more strategic and cost-effective flood risk management responses. This reflects a broader turn towards nature-based soluti

OBJECTIVE: The longitudinal variations in serum levels of the hormone osteocalcin is largely unknown during infancy and early childhood. Our aim was to establish reference limits for total serum osteocalcin during specific time points from birth until 5 years of age and present those in the context of sex, breastfeeding practices and gestational age (GA).DESIGN: Blood samples from 551 Swedish chil

Objective: To describe a retroperitoneal transient occlusion of the uterine or internal iliac artery in conjunction with a high-risk evacuation of products of conception. The procedure was performed vaginally, minimally invasively, via vaginal natural orifice transluminal endoscopic surgery. Design: Description of the surgical technique using original video footage. This study was exempted from re

Deep ice cores from polar ice sheets enable reconstructions of Earth’s past climate. Ice core records are therefore crucial for projecting future climate change, but our ability to interpret them relies on our understanding of polycrystalline-ice microstructures and mechanics. In turn, these microstructures enable modeling of ice flow and large-scale effects of ice sheet evolution. Since drilling

Background: Atherosclerotic cardiovascular disease is a chronic inflammatory process initiated when cholesterol-carrying low-density lipoprotein (LDL) is retained in the arterial wall. CD4+ T cells, some of which recognize peptide components of LDL as antigen, are recruited to the forming lesion, resulting in T-cell activation. Although these T cells are thought to be proatherogenic, LDL immunizat

Purpose The aim of the research was to investigate how a model for public procurement could be designed with the aim of including industrially produced housing in the procurement process in Sweden. Methodological approach The study was performed in two steps, an initial literature review and then a case study. The literature review aimed at creating an understanding of how this is done in other c

Purpose The purpose is to develop a framework for measuring the S&OP process performance. Design/methodology/approach The method used is a multiple case study of five companies from different industries based on data from twelve structured interviews. Findings The main result is a framework to measure the S&OP process. It includes concrete suggestions for organizations when developing me

Aim: The aim of this study was to explore the association between nurses' characteristics (educational level, country, work title, gender, type of work, age, and length of working experience) and their assessments of individualized care. Design: A cross-sectional comparative survey using questionnaires was employed to sample nurses from seven countries. Methods: Data were collected from ort

Syfte: Studiens syfte är att undersöka hur rekryteringsprocesser kan agera som en förebyggande process mot agentproblem. Metod: Via en kvalitativ forskningsmetod genomfördes en enkel fallstudie med hjälp av intervjuer, observationer och dokumentation. Åtta intervjuer och två observationer genomfördes. Data analyserades med en kombination av pattern-matching och grundad teori. Teoretiska perspekt

Dating back to the ancient times, people used simple marks to tell their stories and write their history when languages were not created. As time passes by, there are more and more ways we could choose like writing dairies, taking photos, or using mobile devices to share the stories with friends. We could record almost every second in life easily. On the other hand, we are now facing a huge amount

The scale at which greenhouse gases are produced by human activities is a global problem, and as such it is being targeted broadly both by political means as well as technologically. One of the major contributors to the emission of green house gases globally, as well as in Sweden, is the transportation sector. This poses an opportunity for technologies that aim to reduce impact of the transport se