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Test–retest reliability of Antonovsky’s 13-item sense of coherence scale in patients with hand-related disorders

Purpose: To report on the distribution and test-retest reliability of Antonovsky’s 13-item Sense of Coherence (SOC-13) Scale in patients with hand-related disorders (HRD). Links between the SOC-13 score and factors such as age, number of days between date of injury and start of rehabilitation, gender and educational level were explored. Method: Survey with test–retest, using self-administered ques

Hybrid SSF/SHF Processing of SO2 Pretreated Wheat Straw—Tuning Co-fermentation by Yeast Inoculum Size and Hydrolysis Time

Wheat straw is one of the main agricultural residues of interest for bioethanol production. This work examines conversion of steam-pretreated wheat straw (using SO2 as a catalyst) in a hybrid process consisting of a short enzymatic prehydrolysis step and a subsequent simultaneous saccharification and fermentation (SSF) step with a xylose-fermenting strain of Saccharomyces cerevisiae. A successful

Sleep and circadian rhythm regulation in early Parkinson disease

IMPORTANCE: Sleep disturbances are recognized as a common nonmotor complaint in Parkinson disease but their etiology is poorly understood.OBJECTIVE: To define the sleep and circadian phenotype of patients with early-stage Parkinson disease.DESIGN, SETTING, AND PARTICIPANTS: Initial assessment of sleep characteristics in a large population-representative incident Parkinson disease cohort (N=239) at

N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development

BACKGROUND: Glutathione (GSH) is the major cellular redox-regulator and antioxidant. Redox-imbalance due to genetically impaired GSH synthesis is among the risk factors for schizophrenia. Here we used a mouse model with chronic GSH deficit induced by knockout (KO) of the key GSH-synthesizing enzyme, glutamate-cysteine ligase modulatory subunit (GCLM).METHODS: With high-resolution magnetic resonanc

The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound : The STARTER study

Objective: To define the role of ultrasound (US) for the assessment of patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. Methods: A multicentre longitudinal study has been promoted by the US Study Group of the Italian Society for Rheumatology. 25 Italian centres participated, enrolling consecutive patients with RA in clinical remission. All patie

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To increase the added value of arracacha flour, a soup type food was designed considering the traditional culinary recipes of this root. The methodology applied for this purpose, allowed to obtain the baked flour, and also the characterization of the physicochemical, functional composition, and in vitro digestibility; as well as to propose some formulations varying the flour contents from 40 to 65

How to avoid severe coronary vasoconstriction in potassium induced cardioplegia

Objectives. The aim of this study was to investigate how high K+ concentrations can be safely used in cardioplegic solutions without causing severe coronary artery vasocontraction. Design. Twenty-four 50 kg pigs were used. The distal part of the left anterior descending coronary artery was cut into ring segments and transferred into organ baths with Krebs solution bubbled with 95% O2 and 5% CO2. K

A Detailed Analysis of Internal Resistance of a PEFC Comparing High and Low Humidification of the Reactant Gases

Polymer electrolyte fuel cells (PEFCs) have shown a great potential to be used in several applications, e.g., portable, mobile and stationary systems. Each of the mentioned applications demands from PEFCs different operating conditions to perform in the best possible manner. Knowing in detail the behavior of their internal components will help to improve the mechanical and thermal properties of th

Degraded and restituted towns in Poland: Origins, development, problems

One of the less known problems in settlement geography is the issue of so-called degraded and restituted towns. This lack of reconnaissance, however, is perhaps less the result of the towns’ scarcity than their specificity of being ‘awarded’ or ‘deprived of’ an urban label by means of strictly socio-political actions. Degraded and restituted towns, hence, are spatial units made ‘urban’ or ‘rural’

Fracture characteristics of acetylated young Scots pine

A study on the fracture characteristics of unmodified and chemically modified Scots pine (Pinus sylvestris) is presented. The investigated material consisted of small-dimension sawn timber originating from young logs (thinnings), aged 30–40 years. The modified samples were acetylated with acetic anhydride in an industrial scale process without the use of any catalyst, reaching an acetyl content of

In adults with obesity, copeptin is linked with BMI but is not associated with long-term exposure to cortisol and cortisone

Context: Obesity and cardiometabolic diseases are associated with higher long-term glucocorticoid levels, measured as scalp hair cortisol (HairF) and cortisone (HairE). Cardiometabolic diseases have also been associated with copeptin, a stable surrogate marker for the arginine-vasopressin (AVP) system. Since AVP is, together with corticotropin-releasing hormone (CRH) an important regulator of the

Corticosteroids or Not for Postoperative Nausea : A Double-Blinded Randomized Study

Background: Postoperative nausea and vomiting (PONV) is common after general anaesthesia, and corticosteroids are used in many protocols for enhanced recovery after surgery (ERAS). However, surgical techniques are developing, and ERAS protocols need to be reevaluated from time to time. Patients and method: In this study, we compared the effects of oral vs. parenteral corticosteroid administration

From contamination to infective endocarditis—a population-based retrospective study of Corynebacterium isolated from blood cultures

Corynebacterium is a genus that can contaminate blood cultures and also cause severe infections like infective endocarditis (IE). Our purpose was to investigate microbiological and clinical features associated with contamination and true infection. A retrospective population-based study of Corynebacterium bacteremia 2012–2017 in southern Sweden was performed. Corynebacterium isolates were species

Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers

Background: We aim to estimate population-attributable fractions (PAF) for 13 comorbidities potentially predisposing to hepatobiliary cancer of hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cancers of the intrahepatic and extrahepatic bile ducts (ICC and ECC), and ampullary cancer. Methods: Patients were identified from the Swedish Inpatient Register from 1987 to 2018 and cancers from

What Caregivers Like the Most (and Least) About Cognitive Behavioral Therapy for Youth Anxiety: A Mixed Methods Approach

Cognitive behavioral therapy (CBT) is an efficacious therapy for youth anxiety disorders. Caregivers are key stakeholders in youth therapy, and their feedback on treatment can help to inform intervention personalization. This mixed-methods study applied a systematic inductive thematic analysis to identify themes among most- and least-liked CBT features reported by caregivers using open-ended respo

Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications

Nowadays, superparamagnetic iron oxide nanoparticles (SPIONs) have a dominant role in many subfields of biomedicine. Owing to their peculiar properties, they can be employed for magnetic separation, drug delivery, diagnostics, and hyperthermia treatments. However, these magnetic nanoparticles (NPs) suffer from low unit magnetization due to size constraints (up to 20-30 nm) to exhibit superparamagn

Wolbachia improves the performance of an invasive fly after a diet shift

Polyphagy is an adaptative strategy allowing species to develop and survive on multiple diets. Phytophagous insects can be exposed to sub-optimal resources, as host plants vary in nutritional quality. Some insects may rely on symbiotic bacteria to better utilize less favorable substrates. The invasive fruit fly Drosophila suzukii is a highly successful pest worldwide. The use of ripening and ripe

The Disinformation Economy: Digital Markets of Influence, Conflict, and Polarization

The online information landscape is a site for contested ideas, but it is also a marketplace; under the platform economy, every engagement has monetary value. This setup encourages content creators to circulate the kinds of material most likely to capture attention, even if it is incendiary. Central to this business model are the algorithmic recommendation systems, which are designed to monetize a

Heat and the planning system : how can local authorities encourage deployment of low and zero-carbon heating?

There is widespread recognition of the need for new homes to feature only low or zero-carbon (LZC) heating. However, residential developers continue to choose conventional high-carbon options such as natural gas boilers over net-zero compatible alternatives. This study explores how UK local authorities (LAs) within the English planning system can encourage residential developers to deploy LZC heat