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No consensus treatment regime exists beyond surgery for malignant peripheral nerve sheath tumours (MPNST), and the purpose of the present study was to find new approaches to stratify patients with good and poor prognosis and to better guide therapeutic intervention for this aggressive soft tissue cancer. From a total of 67 MPNSTs from Scandinavian patients with and without neurofibromatosis type 1
Objective: To examine the effect of photodynamic therapy (PDT) on experimental liver tumours in rats. Design: An experimental liver tumour model was used. Each of a group of Fats had two tumours simultaneously inoculated into its liver. The tumour located in the left hepatic robe was used for PDT, and the other one, in the median lobe, as a control. The haem precursor delta-amino laevulinic acid (
Objective : To determine the association between health-risk behaviors and a history of sexual coercion among urban Chinese high school students. Design : A cross-sectional study was performed among 109,754 high school students who participated in the 2005 Chinese Youth Risk Behavior Survey. Data were analyzed for 5,215 students who had experienced sexual intercourse (1,483 girls, 3,732 boys). Mul
Adaptation is essential in maintaining stability during balance-challenging situations. We studied, ill standing subjects with eyes open and closed, adaptive responses of the anteroposterior head, shoulder, hip and knee movements: gastrocnemius and tibialis anterior EMG activity and anteroposterior body Posture when proprioceptive information from the neck or calf muscles underwent vibratory pertu
As climate change have become generally accepted as a potential problem, reducing the greenhouse gas emissions and global energy demand has become an important research topic. This have led to an increased interest towards the retrofitting of the existing building stock, including cultural protected buildings. Due to the cultural protection, carrying out major alteration such as exterior wall retr
Sveriges regering satte 2011 upp mål om att bli bäst på att utnyttja digitaliseringens möjligheter. Digitaliseringen av bygglovsprocessen har trots det gått långsamt. Bygglovsprocessen idag (2018) är en långsam, dyr och ineffektiv process. Möjligheten att söka bygglov med e-legitimation finns endast hos 30 procent av kommunerna och 60 procent har någon slags e-tjänst ansökan. Ansökningarna innebärThe Swedish government set up a goal in 2011 of making the best use of digitization opportunities. The digitization of the building permit process has, however, been slow. The process of building permits is today (2018) a slow, expensive and inefficient process. The possibilities to apply for building permits with e-credentials is only available in 30 percent of municipalities and 60 percent have
Popular Abstract in Swedish Bedömning av höger sida av hjärtat är viktig hos patienter med hjärtsjukdom; i synnerhet hos patienter med förhöjt tryck i lungkretsloppet. Sänkt högerkammarfunktion och förhöjt tryck i höger förmak har visats vara prognostiskt dåligt. Två-dimensionellt ultraljud av hjärtat (ekokardiografi) är den vanligaste metoden för att bedöma hjärtats funktion, men högerkammaren ärAssessment of the right side of the heart is important in patients with heart disease; especially in patient with elevated pressure in the lung circulation. Decreased right ventricular function and elevated pressure in the right atrium are of poor prognostic value. Two-dimensional echocardiography (ultrasound of the heart) is the most commonly used method to assess the hearts function, but the rig
This paper presents a novel method for the analysis of heart rate variability (HRV) during exercise stress testing enhanced with respiratory information. The instantaneous frequency and power of the low frequency (LF) and high frequency (HF) bands of the HRV are estimated by parametric decomposition of the instantaneous autocorrelation function (ACF) as a sum of damped sinusoids. The instantaneous
This study evaluated the sample sizes necessary to estimate several soil and vegetation characteristics within 10% confidence intervals with 95% probability in three terra firme tropical rainforest sites. Across all three plots, the most spatially heterogeneous variables were measurements of total standing crop root mass, ground surface litter mass, litter fall, root growth and soil respiration wh
Purpose: The goal of this research was to evaluate a potential therapeutic agent for breast cancer based on galectin-3 that has been implicated in tumorigenicity and metastasis of breast cancer. The hypothesis was that therapy with NH2-terminally truncated form of galectin-3 (galectin-3C) will be efficacious for reduction in tumor growth and for inhibition of metastases. Experimental Design: Recom
Inhibitors of dihydroorotate dehydrogenase (DHODH) have been suggested for the treatment of rheumatoid arthritis, psoriasis, autoimmune diseases, Plasmodium, and bacterial and fungal infections. Here we present the structures of N-terminally truncated (residues Met30-Arg396) DHODH in complex with two inhibitors: a brequinar analogue (6) and a novel inhibitor (a fenamic acid derivative) (7), as wel
Objective The purpose of this study was to evaluate the effect of wet clothing removal or the addition of a vapor barrier in shivering subjects exposed to a cold environment with only limited insulation available. Methods Volunteer subjects (n = 8) wearing wet clothing were positioned on a spineboard in a climatic chamber (–18.5°C) and subjected to an initial 20 minutes of cooling followed by 3
This thesis outlines the design and construction of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. In acoustic trapping, a strong, localised acoustic field is generated inside a channel. This field can capture and retain particles against a flow, allowing for nanoparticle purification and enrichment without the need for ul
The objective of this study was to investigate potential differences in gender and place of origin on intimate partner violence (IPV) attitudes, self-silencing beliefs, and sexist and feminist measures in a sample of young adults between 18 and 30 years. Furthermore, it examined whether exposure to videos containing either sexist or feminist humour impacted participants’ level of IPV attitudes, se
Syftet med denna uppsats är att undersöka hur avvägningen mellan effektivitet och rättssäkerhet i förarbetena till skattetillägget kommit att påverka hur dagens skattetillägg fungerar i praktiken vid Skatteverkets kontrollverksamhet avseende tjänsteavdrag. Detta redogörs för genom att dagens regelverk och de förarbeten som legat till grund för skattetillägget analyseras i förhållande till effektivThe purpose of this essay is to investigate how the trade-off between efficiency and rule of law during the legislation processes for the tax surcharge has come to affect how today's tax surcharge works in practice regarding the Swedish Tax Agency's monitoring of tax deductions for work-related expenses made by natural persons. This essay will examine this through analyzing today's reg
Breast cancer is the most common cancer type among women. The 5-year survival rate for invasive breast cancer is generally good at approximately 80-85%, however it is not uncommon for late recurrences to develop – the relative survival at 15 years is approximately 60%, in contrast to for example uterine cancer where the 5-year is about 80% and very few late deaths occur (80% survival at 15-years).
Det har sagts att alla arkitekturepoker brukar nå sitt bottenmärke någonstans runt 30 år. Under en praktik på ett arkitektkontor upplevde jag det på egen hand när jag arbetade med ett område i Stockholm. Strategin för området är att riva stora delar av dess bebyggelse från 80- och 90-talet. Jag uppfattar strategin som ett uttryck för en allmän impopularitet av arkitekturen från denna period — den It has been said that all architectural eras tend to reach their lowest point of popularity somewhere in their 30s. During an internship, I experienced it first hand when I worked with an area in development in Stockholm. The strategy for the area was to demolish most of its buildings from the 1980s and 90s, buildings that are relatively young. I perceive the strategy as an expression for a genera
The objective of this thesis was to investigate how double skin facades (DSFs) meet daylight and energy requirements compared to single skin facades (SSFs), also considering the life cycle costing (LLC) of both solutions. A South facing, an unobstructed glazed office building in Sweden was used as a basic building object, where SSFs and DSFs were iteratively applied. A mid-level floor was chosen a
Entrepreneurial intentions have been identified as a relevant precursor to entrepreneurial behavior; however, the complexities of entrepreneurial intention remain under-explored. This study examines the impact of offspring involvement with parental businesses on their entrepreneurial career intentions and the indirect roles of perceived desirability and perceived feasibility. Building primarily on
There is a rising demand for decarbonizing the building sector since it significantly contributes to global carbon emissions. With a focus on the mechanical, electrical, and plumbing systems specifically, this master’s thesis explores the embodied carbon within these building service systems. Utilizing established life cycle assessment methodologies, the case study thoroughly examines the embodied
