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Accelerometer derived physical activity and subclinical coronary and carotid atherosclerosis : cross-sectional analyses in 22 703 middle-aged men and women in the SCAPIS study

OBJECTIVES: The aim included investigation of the associations between sedentary (SED), low-intensity physical activity (LIPA), moderate-to-vigorous intensity PA (MVPA) and the prevalence of subclinical atherosclerosis in both coronaries and carotids and the estimated difference in prevalence by theoretical reallocation of time in different PA behaviours.DESIGN: Cross-sectional.SETTING: Multisite

Dynamic Shear Rheometer for rheological investigation of bitumen in road applications : The impact of measurement technique

The rheological properties of bituminous binders tested with a dynamic shear rheometer (DSR) as a function of loading time and temperature can more accurately represent real road situations with rising traffic loads and densities combined with climatic change. This method is more effective than traditional methods such as measuring the softening point and penetration. Complex shear modulus and pha

Circadian Melatonin Rhythm and Excessive Daytime Sleepiness in Parkinson Disease.

IMPORTANCE Diurnal fluctuations of motor and nonmotor symptoms and a high prevalence of sleep-wake disturbances in Parkinson disease (PD) suggest a role of the circadian system in the modulation of these symptoms. However, surprisingly little is known regarding circadian function in PD and whether circadian dysfunction is involved in the development of sleep-wake disturbances in PD. OBJECTIVE To d

A Randomized Trial of Balloon Kyphoplasty and Non-Surgical Management for Treating Acute Vertebral Compression Fractures: Vertebral Body Kyphosis Correction and Surgical Parameters.

Study Design. Multicenter randomized controlled trial.Objective. To compare the efficacy and safety of balloon kyphoplasty (BKP) to non-surgical management (NSM) over 24 months in patients with painful vertebral compression fractures (VCF).Summary of Background Data. Recently, several large randomized controlled trials have been conducted and reported how vertebral augmentation compares with NSM f

Prospective, longitudinal quality-of-life study of patients with head and neck cancer: a feasibility study including the EORTC QLQ-C30

Despite modern advances in the treatment of head and neck cancer, the survival rate fails to improve. Considering the different treatment modalities involved, quality of life has been thought of as an additional end point criterion for use in clinical trials. A Nordic protocol to measure the quality of life of head and neck cancer patients before, during, and after treatment was established. Befor

Life of Excitons in Artificial Photosynthetic Antennas

Popular Abstract in Swedish På grund av den förutspådda energi krisen som föranleds av att oljan tar slut, är det viktigt att söka efter alternativa energikällor. Att utnyttja solljuset via en artificiell fotosyntes är en intressant möjlighet. Det långsiktiga målet för forskning på detta område är att bygga molekylära och/eller fasta material som kan använda solljus för att dela vatten i dess bestDue to the predicted energy crisis when fossil fuels will be exhausted it is important to search for alternative energy sources. Utilizing sunlight via artificial photosynthesis is an interesting possibility. The long-term goal for research in this area is to design and build molecular and/or solid state systems that can use sunlight to split water and produce fuel (e.g. hydrogen). Nature tells us

Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation - A Randomized trial

Context Inpatients with nonvalvular atrial fibrillation, warfarin prevents ischemic stroke, but dose adjustment, coagulation monitoring, and bleeding limit its use. Objective To compare the efficacy of the oral direct thrombin inhibitor ximelagatran with warfarin for prevention of stroke and systemic embolism. Design, Setting, and Participants Double-blind, randomized, multicenter trial (20002001)

5-ALA for photodynamic photorejuvenation - Optimization of treatment regime based on normal-skin fluorescence measurements

Background and Objectives: Photodynamic therapy using 20% 5 aminolevulinic acid (5-ALA) has recently been introduced as a new tool in optical skin rejuvenation. The primary objective of this study was to optimize incubation time, the topical delivery mechanism (vehicle) and the concentration of 5-ALA by detecting the dynamic changes of normal skin after 5-ALA application. The secondary objective w

Biological vs Conventional Combination Treatment and Work Loss in Early Rheumatoid Arthritis A Randomized Trial

IMPORTANCE The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs over 2 years. OBJECTIVE To investigate whether radiological superiority translates into be

Visual impairment in children born prematurely from 1972 through 1989

PURPOSE: To investigate the incidence and causes of visual impairment in children born prematurely in Finland from 1972 through 1989, and to determine what conditions and factors were associated with its occurrence. DESIGN: Retrospective, cross-sectional study. SUBJECTS: All visually impaired individuals from 0 to 17 years of age who had been born at fewer than 37 gestational weeks in Finland from

The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma

Background: Craniopharyngioma is a parasellar tumour that, although benign, tends to behave aggressively. It can occur at any age but most commonly presents in childhood or adolescence. Objectives: to investigate the frequency and severity of problems associated with craniopharyngioma, using the large international database (KIMS) for adult patients with GH deficiency (GHD), and to assess the diff

Natural History of Open-Angle Glaucoma.

OBJECTIVE: This article, based on the Early Manifest Glaucoma Trial (EMGT), provides prospective natural history data on progression of glaucomatous field defects in 3 of the most common glaucoma types. DESIGN: Cohort of EMGT patients randomized to the untreated control group and followed up to the time of progression, when treatment could be initiated. PARTICIPANTS: We evaluated 118 control patie

Parental alcohol use disorder and offspring marital outcomes

Aims: We tested whether parental alcohol use disorder (AUD) predicted adult offspring's likelihood of marriage and marriage to an AUD-affected spouse; whether effects differed as a function of the sex or number of affected parents; and whether they were robust to confounders. Design: Sex-stratified Cox and logistic regression models. Setting: Sweden. Participants: A total of 1 171 070 individuals

Effects of a multifaceted intervention QI program to improve ICU performance

Background To benefit from the increasing clinical evidence, organisational changes have been among the main drivers behind the reduction of ICU mortality during the last decade. Increasing demand, costs and complexity, amplifies the need for optimisation of clinical processes and resource utilisation. Thus, multidisciplinary teamwork and critical care processes needs to be adapted to profit from

Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy

Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial intelligence (AI)-augmented ESWL and to investigate the potential for machine learning to improve the efficacy of ESWL. Design, setting, and participants: Two-dimensional ultraso

Unveiling the Power of Nostalgia in Fashion Retro Branding and Its Influence on the Brand Perception of Young Consumers

Title: Retro Rewind - Unveiling the Power of Nostalgia in Fashion Retro Branding and Its Influence on the Brand Perception of Young Consumers Date of the Seminar: 31 June 2024 Course: BUSN39 Degree Project in Global Marketing Authors: Juan Bibudis and Tim Mårtensson Supervisor: Tommy Shih Examiner: Mats Urde Keywords: Nostalgia, identity, perception, Consumer Culture Theory (CCT), possessions, con

Toxicity of antibiotics, non-steroid anti-inflammatory drugs (NSAIDs) and selective serotonin reuptake inhibitors (SSRIs) to limnic bacterial communities

Popular science summary Are drugs only drugs for human being? An experiment to see if some of the anthropogenic pharmaceuticals are toxic contaminants for the aquatic environment. All kinds of pharmaceuticals have been using widely and the amount has been increased significantly during the last few decades. Concerns about the occurrence of pharmaceuticals releasing into different matrixes of th

Oj, nu gick det snett – vem betalar? - Entreprenörers ansvar för utvecklingsfel enligt konsumenttjänstlagen

Under 1990-talet och fram till 2007 var det vanligt förekommande att byggnader uppfördes med en så kallad enstegstätad fasadkonstruktion. Det byggdes omkring 15 000 – 30 000 bostadshus med denna konstruktion, vilka omfattar 110 000 – 160 000 bostäder. Ett stort antal av byggnaderna uppförda med den aktuella fasadkonstruktionen fick fukt- och mögelskador redan efter några år. År 2007 uppmärksammaDuring the 1990s and up until 2007, it was common that buildings were erected with a construction method known as External Thermal Insulation Composite System Walls. Around 15 000 – 30 000 residential buildings were built using this method and these constitute 110 000 – 160 000 residences. A large number of the buildings constructed with the this method got damp and mold damage after only a few y

Insikt och närvaro : akademiska kontemplationer kring buddhism, meditation och mindfulness

Popular Abstract in Swedish Under 1900-talet har stora förändringar skett i synen på buddhistisk meditation. Från att ha varit en övning som bara ägt rum på kloster och bland ett fåtal munkar, har både ordinerade lärare och lekmannalärare börjat lära ut meditation till lekfolk. Meditation har kommit att framställas som själva hjärtat i buddhistiska traditioner, och som det element som kan isolerasThe purpose of this study is to investigate how a religious tradition changes when transposed to a new context: how it is received and incorporated in its new context and how individuals in Sweden perceive and make use of this tradition. This is done by highlighting the development of insight meditation, Vipassana, and more specifically, the Burmese practice lineage originating from the Burmese la