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The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus

Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.

Engineering of pyranose 2-oxidase: Improvement for biofuel cell and food applications through semi-rational protein design

Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac

Peruvian Trainee Teachers as Mestizas. Pedagogies of Tolerance and Respect Towards Gay and Lesbian People

Given the polarized political context in Peru that was provoked by the inclusion of LGTBIQ+ identities in the official school curriculum, this study analyzes the meanings that students of pedagogy in Lima ascribe to tolerance and respect towards gay and lesbian people, and how these meanings inform their pedagogical practices. Based on two focus groups and eight individual interviews grounded in s

Litteraturlista Den Mångdimensionella Musikläraren Ht22T

Lägg till titel Sida 1 av 3 Ämneslärarutbildning i musik Datum 2022-06-20 Litteraturlista Den Mångdimensionella Musikläraren ht 2022 Beghetto, Ronald. A. (2021). Creativity in K-12-schools. In Sternberg, R. J. & Kaufman, J. C. (Eds.). Creativity: An introduction. Cambridge University Press. (s. 224-236) [13 sidor, se pdf i Canvas] Björkman, Lotta. (2019) Om att förstå vad vi inte förstår för

https://www.mhm.lu.se/sites/mhm.lu.se/files/2022-06/Litteraturlista%20Den%20Ma%CC%8Angdimensionella%20Musikla%CC%88raren%20ht22T.pdf - 2026-05-26

Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest

BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p

EU Horizon Europe - sök utlysningar inom medicin

På denna sida har vi samlat utlysningar inom EU:s ramprogram Horizon Europe som är särskilt intressanta för dig som är verksam vid Medicinska fakulteten. SnabblänkarAllmän informationOm utlysningarnaAktuella och kommande utlysningar Allmän informationHorisont Europa (Horzion Europe) är EU:s ramprogram för forskning och innovation för 2021–2027 med en total budget på nära 95,5 miljarder euro. Progr

https://www.intramed.lu.se/forska/anslag-och-stipendier/eu-projekt-lar-mer-och-sok-och-utlysningar/eu-horizon-europe-sok-utlysningar-inom-medicin - 2026-05-26

Measuring Mindfulness: Pilot Studies with the Swedish Versions of the Mindful Attention Awareness Scale and the Kentucky Inventory of Mindfulness Skills.

The present article describes data from pilot studies with the Swedish versions of the Mindful Attention Awareness Scale (MAAS) and the Kentucky Inventory of Mindfulness Skills (KIMS). The MAAS and two of the KIMS scales, Act with Awareness and Accept without Judgment, were found to correlate in the predicted direction with measures of well-being and emotional distress. The KIMS scales Observe and

Protein Engineering Allows for Mild Affinity-based Elution of Therapeutic Antibodies

Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl