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The convergence properties of different updating methods for the multipliers in augmented Lagrangians are considered. It is assumed that the updating of the multipliers takes place after each line search of a quasi-Newton method. Two of the updating methods are shown to be linearly convergent locally, while a third method has superlinear convergence locally. Modifications of the algorithms to ensu
Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteo
The operator Riccati equation associated with a distributed parameter quadratic cost-linear dynamics control process is considered.Making use of ideas from transport theory, a derivation of a generalized version of the X-Y functions of radiative transfer is given, and it is seen that, under commonly occurring conditions, the new equations may be easier to numerically resolve than the original Ricc
In this thesis, we draw inspiration from both classical system identification and modern machine learning in order to solve estimation problems for real-world, physical systems. The main approach to estimation and learning adopted is optimization based. Concepts such as regularization will be utilized for encoding of prior knowledge and basis-function expansions will be used to add nonlinear model
The understanding of protein interactions to control phase and nucleation behavior of protein solutions is an important challenge for soft matter, biological and medical research. Here, we present ion bridges of multivalent cations between proteins as an ion-activated mechanism for patchy interaction that is directly supported by experimental findings in protein crystals. A deep understanding of e
The general aim of the research programme SPEAK (Sustainable Planning andEnvironmental Assessment Knowledge, www.speakproject.se) was to generateknowledge on, and to strengthen the role of strategic environmental assessment(SEA) in planning as a measure to attain the environmental quality objectives andto promote sustainable development. The SPEAK programme had atransdisciplinary point of departur
Research has been performed model the dynamics of different kinds of wastewater treatment systems. Plant models are built up from standard modules of subprocesses. Available model knowledge has been packaged into suitable software modules and a library of simulation models has been created. The paper describes this library and the kind of simulations that can be performed.
The purpose of this study is to compare three different methods for determining the thermal diffusivity of a one dimensional heat diffusion process. A modifiedA˚ngstro¨m's method, an on-line least squares method and a maximum likelihood method have been applied to data obtained from experiments on a long copper rod. The accuracy, the amount of computation, the storage capacity and in general the a
Ichthyosaurs are extinct marine reptiles that display a notable external similarity to modern toothed whales. Here we show that this resemblance is more than skin deep. We apply a multidisciplinary experimental approach to characterize the cellular and molecular composition of integumental tissues in an exceptionally preserved specimen of the Early Jurassic ichthyosaur Stenopterygius. Our analyses
Timber-concrete composite structures (TCCs) are widely gaining interest in Europe and America, because of its high strength and low energy-consumption structure. The key design point of timber-concrete composite structures are to ensure the reliability of the shear connectors. The objective of this paper was to predict structural response with finite element (FE) analysis and provide shear propert
Since the 1980s, China’s central government has created various model and incentive schemes aimed at systematically and concurrently promoting innovative approaches for protecting the urban ecological environment. In this context, programmes such as the ‘model city for protecting the environment’, ‘garden city’, ‘eco-city’, or ‘low-carbon city’ have become an integral part of China’s system for ur
The kaonic deuterium measurement at J-PARC and DAΦNE will provide a piece of information still missing to the antikaon-nucleon interaction close to threshold, providing valuable information to answer one of the most fundamental problems in hadron physics today - to the yet unsolved puzzle of how the hadron mass is generated. For this a new X-ray detector system has been developed to measure the sh
OBJECTIVES: Early extubation in adults undergoing surgery for congenital heart disease has not been described. The authors report their experience with extubation in the operating room (OR), including factors associated with the decision to defer extubation to a later time.DESIGN: A retrospective chart review.SETTING: A tertiary-care teaching hospital.PARTICIPANTS: This study included adults under
Pairwise comparison of sound and radio signals can be used to estimate the distance between two units that send and receive signals. In a similar way it is possible to estimate differences of distances by correlating two received signals. There are essentially two groups of such methods, namely methods that are robust to noise and reverberation, but give limited precision and sub-sample refinement
Cerebral palsy is the commonest cause of severe childhood disability, the aetiology of which is largely unknown. Data on familial aggregation of cerebral palsy are very limited. We defined familial risks for siblings who were hospitalised because of cerebral palsy in Sweden. A nationwide database for neurological diseases was constructed by linking the Multigeneration Register to the Hospital Disc
OBJECTIVE: We used the nationwide Swedish Family-Cancer Database to analyze the risk for adult (15-61 years) brain tumors in offspring through parental cancer probands. Additionally, cancer risks were assessed among siblings of brain tumor probands.METHODS: In offspring and parents, respectively, 5,425 and 20,938 cases of brain tumors were diagnosed between the years 1958 and 1996. Groups of offsp
