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Quantifying the influence of urban biotic and abiotic environmental factors on great tit nestling physiology

There is a long history of avian studies investigating the impacts of urbanization. While differences in several life-history traits have been documented, either between urban and rural populations or across generalized urbanization gradients, a detailed understanding of which specific environmental variables cause these phenotypic differences is still lacking. Here, we quantified several local en

Role of Amide Proton Transfer Weighted MRI in Predicting MGMTp Methylation Status, p53-Status, Ki-67 Index, IDH-Status, and ATRX Expression in WHO Grade 4 High Grade Glioma

Objectives: To assess amide proton transfer weighted (APTw) MR imaging capabilities in differentiating high-grade glial tumors across alpha-thalassemia/mental retardation X-linked (ATRX) expression, tumor-suppressor protein p53 expression (p53), O6-methylguanine-DNA methyltransferase promoter (MGMTp) methylation, isocitrate dehydrogenase (IDH) status, and proliferation marker Ki-67 (Ki-67 index)

RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells

Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in vaccination, autoimmunity, and cancer. Here, we use fate mapping, functional analyses, and comparative cross-species transcriptomics to show that RORγt+ DCs are a co

Schema mvet11 h15 v4

0000002015-09-17 Badger, 2015. When big gentrification fights are about more than affordable housing. Boverket, 2010. Planer som styrmedel för att minska samhällets klimatpåverkan. CNT, 2010. The Value of Green Infrastructure – A Guide to Recognizing Its Economic, Environmental and Social Benefits. Läs sidorna 1-25. Delshammar, 2012. Stadsodling – Reflektioner och perspektiv från SLU Alnarp. Läs s

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet11_h15_v4.pdf - 2026-06-01

Deep learning-driven investigation of nanoplastic impacts on soil protist behavior in soil chips

Nanoplastics are emerging environmental contaminants that increasingly threaten soil ecosystems, yet their effects on microbial behavior remain poorly understood. This is mainly due to the lack of experimental tools capable of directly observing microbial dynamics in situ under realistic soil-like conditions. Here, we present a proof-of-concept system that enables real-time, high-throughput monito

Operando hysteresis of a palladium surface during high-frequency gas-pulsing of ethylene into oxygen

Catalytic active phases are often separated from inactive ones by their appearance/removal in heating/cooling experiments. Such experiments can reveal ignition, extinction, and often an associated hysteresis. The corresponding behavior and hysteresis under rapid gas composition changes in the milliseconds regime remain largely unexplored. However, such experiments can potentially be highly rewardi

Stabilization of adhesions controls F-actin architecture in mechanotransduction

A cell’s ability to sense and respond to the mechanical properties of the extracellular matrix (ECM) is essential for maintaining tissue homeostasis, and its disruption contributes to diseases such as fibrosis, cardiovascular disorders, and cancer. Effective mechanical coupling between the plasma membrane, the underlying filamentous actin (F-actin) cytoskeleton, and integrin-based adhesion complex

Sambandet mellan finansiella nyckeltal och aktieavkastning på svenska large-cap bolag - En kvantitativ studie av de 50 största bolagen på Nasdaq Stockholm

Research question: To what extent do ROC, EBIT growth, leverage ratio and FCF margin explain variations in stock returns among the 50 largest companies listed on the Stockholm Exchange during the period 2014 - 2024. Purpose: The purpose of this study is to examine the relationship between the financial ratios ROC, EBIT growth, leverage ratio and FCF-margin and stock price development among the 50

PAH exposure and associated health risks can be high at a fire site both during fire and long after the fire is extinguished

The International Agency for Research on Cancer has recently classified occupational exposure as a firefighter as carcinogenic (group 1A). Even though the occupation of firefighter is associated with high exposure to pollutants, it is challenging to carry out exposure studies to assess health risks due to the extreme conditions associated with firefighting. Routine monitoring of occupational expos

From observation to understanding : A multi-agent framework for smart microscopy

Smart microscopy represents a paradigm shift in biological imaging, moving from passive observation tools to active collaborators in scientific inquiry. Enabled by advances in automation, computational power, and artificial intelligence, these systems are now capable of adaptive decision-making and real-time experimental control. Here, we introduce a theoretical framework that reconceptualises sma

A municipality implemented behavioural intervention to improve quality of life among older adults : protocol for a mixed-methods pilot case study

BACKGROUND: Ageing is associated with circadian rhythm sleep disorders, poor sleep at night, less physical activity and more time spent indoors, affecting the wellbeing of older adults. Their sleep and mood could benefit from daytime outdoor physical activity, exposure to daylight, better indoor lighting and sleep routines. However, changes to routines can be challenging depending on individual be

Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells

Here, we present a workflow for transcriptional silencing of transposable elements (TEs) in human induced pluripotent stem cells (hiPSCs). We describe steps for designing guide RNAs (gRNAs) to target TE families or unique TE loci. We also detail procedures for validating the efficiency and specificity of large-scale CRISPRi-based silencing using a multiome approach combining bulk RNA sequencing, C

An integrated Biobank in the Swedish Heart Failure Registry - clinomics, proteomics, transcriptomics and genomics

AIMS: To build a comprehensive biobank integrated in the Swedish Heart Failure Registry (SwedeHF) comprising comprehensive clinomic data, proteomic, transcriptomic and genomic information in combination with clinical and diagnostic characteristics and additional ICD-code registry data.METHODS: Blood and urine samples will be biobanked at SwedeHF registration with an optional second sampling after

Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons

Alzheimer’s disease (AD) is the most common cause of dementia, costing about 1% of the global economy. Failures ofclinical trials targeting amyloid-βprotein (Aβ), a key trigger of AD, have been explained by drug inefficiency regardlessof the mechanisms of amyloid neurotoxicity, which are very difficult to address by available technologies. Here, wecombine two imaging modalities that stand at oppos

The Perception of Inclusion Through the Perspective of Employees

Talking about inclusion in the workplace is an emerging concept, and the pressure of committing to work with it rests on the companies. The research conducted around inclusion is growing, and there are different suggestions as to how to define and work with the concept. Moreover, companies are lacking evidence to support how to successfully measure it among employees. By exploring inclusion in a s

Visualizing, Analyzing and Managing the Scope of Software Releases in Large-Scale Requirements Engineering

Popular Abstract in English Large market-driven software companies face new challenges in requirements engineering and management that emerged due to their recent extensive growth. At the same time, the pressure generated by competitors’ and users’ expectations demands being more competitive, creative and flexible to more quickly respond to a rapidly changing market situation. In the pursuit of stLarge market-driven software companies face new challenges in requirements engineering and management that emerged due to their recent extensive growth. At the same time, the pressure generated by competitors’ and users’ expectations demands being more competitive, creative and flexible to more quickly respond to a rapidly changing market situation. In the pursuit of staying competitive in this co

Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.

Studies of developmental pathways of hematopoietic stem cells (HSCs) have defined lineage relationships throughout the blood system. This is relevant to acute myeloid leukemia (AML), where aggressiveness and therapeutic responsiveness can be influenced by the initial stage of transformation. To address this, we generated a mouse model in which the mixed-lineage leukemia/eleven-nineteen-leukemia (M

Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification.

Appropriate regulation of hematopoietic stem cell (HSC) numbers and function is a requisite for life-long blood cell replenishment. Knowledge of factors that regulate HSC activity is derived largely from murine model systems, with serial transplantation often considered a "gold standard" to assess longevity and self-renewal of HSCs. In the literature, we noted inconsistencies in how serial transpl