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The evolution of suppressed recombination between sex chromosomes is widely hypothesized to be driven by sexually antagonistic selection (SA), where tighter linkage between the sex-determining gene(s) and nearby SA loci is favored when it couples male-beneficial alleles to the proto-Y chromosome, and female-beneficial alleles to the proto-X. Although difficult to test empirically, the SA selection
Working with pushbroom imagery in photogrammetry and remote sensing presents a fundamental challenge in object-to-image space transformation. For this transformation, accurate estimation of Exterior Orientation Parameters (EOPs) for each scanline is required. To tackle this challenge, Best Scanline Search or Determination (BSS/BSD) methods have been developed. However, the current BSS/BSD methods
This piece is a comparative analysis of major parties’ manifesto pledges on AI for the 2024 UK general election.
Both trio and population designs are popular study designs for identifying risk genetic variants in genome-wide association studies (GWASs). The trio design, as a family-based design, is robust to confounding due to population structure, whereas the population design is often more powerful due to larger sample sizes. Here, we propose KnockoffHybrid, a knockoff-based statistical method for hybrid a
Presented is the search for anomalous Higgs boson decays into two axion-like particles (ALPs) using the full Run 2 data set of 140fb-1 of proton-proton collisions at a centre-of-mass energy of 13TeV recorded by the ATLAS experiment. The ALPs are assumed to decay into two photons, providing sensitivity to recently proposed models that could explain the (g-2)μ discrepancy. This analysis covers an AL
Economic behavior highlights the importance of differences in individual characteristics like cognition and emotional regulation strategy in predicting the selection and performance of economic choices. However, the literature on value premium has overlooked the effect of cognition and emotional regulation strategy in assessing individual preference to select value versus growth stocks. We fill th
RNA sequencing (RNAseq) methodology has experienced a burst of technological developments in the last decade, which has opened up opportunities for studying the mechanisms of adaptation to environmental factors at both the organismal and cellular level. Selecting the most suitable experimental approach for specific research questions and model systems can, however, be a challenge and researchers i
This paper presents a novel method to access lived religion and magical practices of a Medieval congregation via sermons combined with material culture. Previously, scholars have dismissed sermons as having low ‘truth value’ due to the copying inherent in the genre. In this paper, I first examine how one Danish sermon was adapted from a German model to fit a local context. This adaptation reveals
Biomass residues are often considered key in a reorientation towards circular bioeconomies, both by returning organic matter and nutrients to soils and by expanding the feedstock base for fossil-free products. Different indicators are available to assess progress towards circularity, but many available indicators and assessments seem to focus on product or material circularity, and lack in coverag
In Sweden, urban planners are legally obligated to design neighbourhoods that allow future buildings to meet daylight requirements. However, this is challenging because planners can only define the building masses, without control over future building details such as glazing ratios, room layouts, and orientation.The Vertical Sky Component (VSC) is a well-established indicator for early daylight as
The importance of reducing environmental impacts has gained speed in the contemporary global context. Stabilization/Solidification (S/S) has become a practical method for handling polluted dredged sediments to make them usable as a construction material. This study aims to evaluate the environmental and economic impacts of a 48,586 m2 port, with stabilized dredged sediment, by focusing on the prod
BACKGROUND: After over a decade of developments in field collection, laboratory methods and advances in high-throughput sequencing, contamination remains a key issue in ancient DNA research. Currently, human and microbial contaminant DNA still impose challenges on cost-effective sequencing and accurate interpretation of ancient DNA data.RESULTS: Here we investigate whether human contaminating DNA
Escherichia coli BL21 (DE3) with a plasmid vector pET-22b (+) carrying xylanase coding gene isolated from an extremely thermophilic bacterium, Thermotoga sp. was used in this work for enhanced production of recombinant xylanase. The study was focused on optimization of lactose based induction for enhanced production of xylanase. Data collected from OFAT and DoE based trails indicated that initiati
Background: Evidence was found for the effectiveness of virtual reality-based cognitive behavioral therapy (VR-CBT) for treating paranoia in psychosis, but health-economic evaluations are lacking. Objective: This study aimed to determine the short-term cost-effectiveness of VR-CBT. Methods: The health-economic evaluation was embedded in a randomized controlled trial evaluating VR-CBT in 116 patien
We investigate the use of atmospheric oxygen (O2) and carbon dioxide (CO2) measurements for the estimation of the fossil fuel component of atmospheric CO2 in the UK. Atmospheric potential oxygen (APO) - a tracer that combines O2 and CO2, minimizing the influence of terrestrial biosphere fluxes - is simulated at three sites in the UK, two of which make APO measurements. We present a set of model ex
Background: Refugees and asylum-seekers have an elevated risk of mental health issues, such as depression and posttraumatic stress. Qualitative outcome studies can contribute by offering insight into patients’ experiences of what they find beneficial and how they undergo the process of recovery. This study aligns with the small body of qualitative research focusing on refugees’ perspectives of psy
