Filtyp
BACKGROUND: Screening immigrant mothers for postpartum depression has been shown to be challenging for health care professionals in handling cultural implications of postpartum depression, communicating through interpreter and applying translated versions of the screening scale.AIM: The aim of the study was to test the feasibility of an evidence-based educational intervention for Child Health Serv
Assessing the causal effects of individual dietary macronutrients and cardiometabolic disease is challenging owing to the complexity to distinguish direct effects from those mediated or confounded by other factors. To estimate these effects, intake of protein, carbohydrate, sugar, fat, and its subtypes were obtained using food frequency data derived from a Swedish population-based cohort (n~60,000
There is a large interest in predicting high-pressure homogenizer (HPH) valve hydrodynamics using CFD, in academic research and industrial R&D. Most of these studies still use two-equation RANS turbulence models, whereas only a few have used LES formulations. From a theoretical perspective, LES is known to be more accurate than RANS, especially in terms of estimating the dissipation rate of tuThere is a large interest in predicting high-pressure homogenizer (HPH) valve hydrodynamics using CFD, in academic research and industrial R&D. Most of these studies still use two-equation RANS turbulence models, whereas only a few have used LES formulations. From a theoretical perspective, LES is known to be more accurate than RANS, especially in terms of estimating the dissipation rate of tu
Using multilayer zone plates (MZPs) as two-dimensional optics, focal spot sizes of less than 10 nm can be achieved, as we show here with a focus of 8.4 nm × 9.6 nm, but the need for order-sorting apertures prohibits practical working distances. To overcome this issue, here an off-axis illumination of a circular MZP is introduced to trade off between working distance and focal spot size. By this, t
Purpose: The application of automated image analyses could improve and facilitate standardization and consistency of quantification in [18F]DCFPyL (PSMA) PET/CT scans. In the current study, we analytically validated aPROMISE, a software as a medical device that segments organs in low-dose CT images with deep learning, and subsequently detects and quantifies potential pathological lesions in PSMA P
The prevalence of type 2 diabetes (T2D) is increasing worldwide, but current treatments have limitations. miRNAs may play a key role in the development of T2D and can be targets for novel therapies. Here, we examined whether T2D is associated with altered expression and DNA methylation of miRNAs using adipose tissue from 14 monozygotic twin pairs discordant for T2D. Four members each of the miR-30
Background: Radical prostatectomy reduces mortality among patients with localised prostate cancer. Evidence on whether different surgical techniques can affect mortality rates is lacking. Objective: To evaluate functional and oncological outcomes 8 yr after robot-assisted laparoscopic prostatectomy (RALP) and open retropubic radical prostatectomy (RRP). Design, setting, and participants: We enroll
Astrocytes are essential cells for normal brain functionality and have recently emerged as key players in many neurological diseases. However, the limited availability of human primary astrocytes for cell culture studies hinders our understanding of their physiology and precise role in disease development and progression. Here, we describe a detailed step-by-step protocol to rapidly and efficientl
Supercritical n-decane is applied in the regenerative cooling system of scramjet engines while scramjets are always in various irregular movements. With the desire to explore heat transfer performance of supercritical n-decane under actual flight conditions, numerical simulations and analysis of different states during the accelerated flight process are carried out under three different heat fluxe
Background - Comorbidity between psychiatric disorders is extensive but, from a genetic perspective, still poorly understood. Modern molecular genetic approaches to this problem are limited by a reliance on case-control designs. Methods - In 5 828 760 individuals born in Sweden from 1932-1995 with a mean (s.d.) age at follow-up of 54.4 (18.1), we examined family genetic risk score (FGRS) profiles
Neurodegenerative disorders are common and heterogeneous in terms of their symptoms and cellular affectation, making their study complicated due to the lack of proper animal models that fully mimic human diseases and the poor availability of post-mortem human brain tissue. Adult human nervous tissue culture offers the possibility to study different aspects of neurological disorders. Molecular, cel
The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly European ancestry. We detected 241 associations, including 30 new loci. Cross-ancestry meta-analysis with a
Aims: The aim of the study was to describe child health in relation to housing renovations in more than 800 rental units, consisting of repairs of dilapidated kitchens and bathrooms, in the disadvantaged neighbourhood of Herrgården in Rosengård, Malmö, Sweden. Methods: Data on housing conditions and self-reported health were collected during home visits to families living in Herrgården (building r
Decisions to admit or refuse admission to intensive care for acute exacerbations of COPD (AECOPD) can be difficult, due to an uncertainty about prognosis. Few studies have evaluated outcomes after intensive care for AECOPD in patients with chronic respiratory failure requiring long-term oxygen therapy (LTOT). In this nationwide observational cohort study, we investigated survival after first-time
Hip-related pain is an umbrella term encompassing pain from non-arthritic hip joint pathologies, such as femoroacetabular impingement syndrome, hip dysplasia, and labral tears. Exercise therapy is commonly recommended for these conditions, but the reporting completeness of these interventions is currently unclear. Purpose The aim of this systematic review was to assess the reporting completeness o
Collaboration between academia and society has become a key priority for many higher education institutions (HEIs). In Sweden, this is partly driven by political calls to secure the long-term provision of knowledge, innovation and competitiveness. At the system and institutional level, responses to this are reflected in governance structures and strategic documents. However, those strategic respon
When biomass is used to produce fuels and green products by thermochemical conversion, the ability to handle or remove the fine particle phase in the product gas is crucial. The product gas from biomass gasification contains relatively volatile organic compounds (“tar”) condensed on nonvolatile cores of, for example, aggregated soot particles and char. The problems are, for example, that particles
This paper discusses the results of a time-dynamic analysis of the possible effects of government and utility-sponsored energy-efficiency programs on electric energy use in Swedish commercial buildings. In the study, which includes efficient lighting, improvements in ventilation, commercial cooling and cooking, we use energy scenarios to analyse how policy measures can effect future energy demand.
The patient with unilateral trans-tribal amputation for vascular disease. Functional assessments, prognostic factors and cost of prostheses. The aims of the study were to focus on the functional ability of the dysvascular patient with unilateral trans-tibial amputation and the early rehabilitation period, defined here as the period between the amputation and the prosthetic fitting. Results revea
