Filtyp
Background: The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood. Research Design and Methods:Given that the genetic background contributes to both traits, it is conceivable that genetic variants associated with T2D may also
Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity against multidrug, extensive and pandrug-resistant war-wound isolates from Ukraine.Materials and methods: We tested 215 clinical samples (2022-2023) isolated from wounded patients
OBJECTIVES: To assess whether the triage model Sepsis Alert for Emergency Departments results in improved initial care of patients with severe infections. DESIGN: Interventional study comparing patient care before and after the start of a new triage model, including 90-day follow-up. SETTING: Eight emergency departments in Skåne County, Sweden. SUBJECTS: Patients with suspected severe infection. I
Background: Little is known about whether the protective effect of marriage on alcohol use disorder (AUD) varies by cultural background. Aims: Using Swedish national data, we examined whether marriage is associated with a stronger reduction in AUD risk among Swedes of a Swedish background (i.e. those with two Swedish-born parents) compared to Swedes with a foreign background (i.e. one or two forei
Background: The consumption of sugar-sweetened beverages (SSBs), which has increased substantially during the last decades, has been associated with obesity and weight gain. Objective: Common genetic susceptibility to obesity has been shown to modify the association between SSB intake and obesity risk in 3 prospective cohorts from the United States. We aimed to replicate these findings in 2 large
Background: Chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cell (CRTh2) receptor antagonists is being investigated for asthma. Objectives: The aim of this study was to assess the effects of the CRTh2 receptor antagonist, AZD1981 (with/without inhaled corticosteroids [ICSs]), on lung function and asthma control. Patients and methods: Adults aged 18–60 years were enr
Background: Liver disease and dementia are both highly prevalent and share common pathological mechanisms. We aimed to investigate the associations between metabolic dysfunction-associated fatty liver disease (MAFLD), metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of all-cause and cause-specific dementia. Methods: We conducted a prospective study with 403,506 partici
Background: Indoor lighting, exposure to outdoor daylight, physical activity and sleep interact to influence functioning, mood and cicadian rhythm. Older adults (≥ 65 years), who often spend more time at home, are less physically active and experience more sleep problems, could benefit from strategies to support behavioural change and self-managed modifications in the home. The study’s primary objBackgroundIndoor lighting, exposure to outdoor daylight, physical activity and sleep interact to influence functioning, mood and cicadian rhythm. Older adults (≥ 65 years), who often spend more time at home, are less physically active and experience more sleep problems, could benefit from strategies to support behavioural change and self-managed modifications in the home. The study’s primary objec
BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world
Purpose: Paleolithic Diet Fraction (PDF) estimates how large a portion of the absolute dietary intake stems from food groups included in the Paleolithic diet. In randomized controlled trials higher PDFs have been associated with healthier levels of cardiometabolic risk markers. Our aim was to build upon these findings by examining associations between PDF and mortality and incidence of cardiometab
Background: The influence of familial factors on the prognosis of ischemic stroke (IS) is unknown. This nationwide follow-up study evaluated familial mortality risks of IS among Swedish sibling pairs hospitalized for IS. Methods: We linked Swedish nationwide registers for the identification of 1380 Swedish born sibling pairs (2760 cases), where both siblings were hospitalized for first-time IS bet
BACKGROUND: Obesity is strongly associated with the development of cardiovascular disease (CVD). However, the heterogenous nature of obesity in CVD-risk is still poorly understood. We aimed to explore novel CVD biomarkers and their possible association with presumed unhealthy obesity, defined as hospitalized subjects with obesity (HO).METHODS: Ninety-two proteins associated with CVD were analyzed
Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac
Electric power grids have a limited capacity for safe and reliable transfer of power. Due to the ongoing large-scale expansion of variable renewable energy sources, such as wind and solar, there is a growing need for rapid gridcapacity increase.This thesis explores methods for improving and expanding grid capacity through control of converter-interfaced energy resources, including wind and solar p
dmrr2427 557..567 Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY Kendra Vehik1* Steven W. Fiske1 Chad A. Logan1 Daniel Agardh2 Corrado M. Cilio2 William Hagopian3 Olli Simell4 Merja Roivainen5 Jin-Xiong She6 Thomas Briese7 Sami Oikarinen8 Heikki Hyoty8,9 Anette-G. Ziegler10 Marian Rewers11 Ake Lernmark2 Beena Akolkar12 Jeffr
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/27%2006032016_679_27_Vehik_DMRR_2013.pdf - 2026-07-08
Brevmall Datum 201X-XX-XX Diarienummer U 201X/XXX KURSPLAN Kursplan för kursen Hållbar markanvändning, NMV004F Engelsk titel: Sustainable Land Use Kursplanen är fastställd av fakultetens nämnd för utbildning på forskarnivå 2020- 12-XX. Kursen ges på forskarnivå och omfattar 7,5 högskolepoäng Lärandemål Hållbar markanvändning är en central komponent för att uppnå FN:s globala hållbarhetsmål. Beslut
https://www.sustainability.lu.se/sites/sustainability.lu.se/files/2021-01/NMV004F-SustainableLandUseAgenda2030.pdf - 2026-07-08
Tentamen 2007-03-09 Uppgift 1 En patient har ordinerats strålbehandling med två motstående fält för en metastas i en ryggkota, se figur nedan. I punkt A (som också är isocenter) önskas 30 Gy, uppdelat på 10 fraktioner. För att åstadkomma en homogen dos i target vill man ha så lika vikt som möjligt för de båda fälten. I punkt B, som representerar tarmarna, vill man emellertid inte överstiga 2.5 Gy
https://www.msf.lu.se/sites/msf.lu.se/files/7._ovningsuppgifter.pdf - 2026-07-08
