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High-energy synchrotron X-ray diffraction offers the unique combination of high spatial resolution and bulk material penetration power, which is well suited for the investigation of strain fields around cracks in engineering materials. The speed of data acquisition also lends itself to the observation of in-situ processes, such as crack propagation. This potential has been only partially explored

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Background: The concerted effects of changes in gene expression due to changes in the environment are ultimately reflected in the metabolome. Dynamics of metabolite concentrations under a certain condition can therefore give a description of the cellular state with a high degree of functional information. We used this potential to evaluate the metabolic status of two recombinant strains of Sacchar

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The current control design development process in automotive industry and elsewhere involves many expensive experiments and hand-tuning of control parameters. Model based control design is a promising approach to reduce costs and development time. In this process low complexity models are essential and model reduction methods are very useful tools. This thesis combines the areas of modeling and mo

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Two main topics are considered in this thesis: Machining with industrial robot manipulators and optimal motion control of robots and vehicles. The motivation for research on the first subject is the need for flexible and accurate production processes employing industrial robots as their main component. The challenge to overcome here is to achieve high-accuracy machining solutions, in spite of the

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Force sensing provides robots the capability to accomplish tasks where physical interaction with the environment is required, such as assembly. Small position uncertainties can then be corrected for by sensing the contact forces. This thesis considers the problem of force-controlled assembly, including how tasks can be specified in a simple and intuitive way and how robust task execution under unc

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The purpose of this study was to explore neuroretinal transplantation in a large animal model of severe retinitis pigmentosa and to establish graft development, long-term survival, graft-host integration, and effects on the host retina. Methods Rhodopsin transgenic pigs, aged 6 months, received in one eye a fetal full-thickness neuroretinal sheet in the subretinal space by means of vitrectomy and

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Popular Abstract in Swedish Dagens storskaliga tillverkning baseras på varor med relativt kort livstid och lågt pris. Vinsterna för tillverkarna kommer från den stora mängden sålda varor. Det finns dock inom många industribranscher krympande vinstmarginaler och många företag söker därför efter nya källor för att uppnå bättre rörelseresultat. Även miljöfrågorna är en utmaning för industrin. VäxandeLife cycle environmental problems have been addressed by a number of strategies. However, the results are mostly lamentable because solutions are searched for within the same paradigms that give rise to the problems. This research questions the vision of linear material growth and searches for ways to sustain economic growth without putting the natural environment under stress. The research explor

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Purpose: To describe the clinical phenotype of the complete type of X-linked congenital stationary night blindness (CSNB1) with different types of mutations in the NYX gene. Methods: The clinical and genetic data from 18 male patients with eight different mutations from two ophthalmological institutes were reviewed. The variability in refractive error, reduced visual acuity and full-field electror

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Abstract in UndeterminedThe use of a polar diagram method for describing and evaluating the machinability ofInconel 718 was explored. Five key parameters of the work material, representing themechanical and physical properties, which have the strongest influence on its machinability,were employed in the diagrams. These five parameters were integrated into asingle polar diagram, used to describe th

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Although Moral Foundations Theory claims that the foundations of morality are universal, there are still few studies addressing it through non-English measures. In the current research, 540 persons filled out a Swedish translation of the Moral Foundations Questionnaire, and 332 of them filled out political attitude measures. Confirmatory factor analyses suggested that the fit of the five-factor mo

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Purpose – The purpose of this paper is to provide a theoretical framework for conceptualizing critical and creative thinking within doctoral study and to illuminate the connecting and diverging points between the two phenomena in a way that clarifies their developmental relationships. Design/methodology/approach – The conceptual framework is founded in a synthesized understanding of both new and

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Many psychiatric illnesses are associated with early mortality and with an increased risk of developing physical diseases that are more typically seen in the elderly. Moreover, certain psychiatric illnesses may be associated with accelerated cellular aging, evidenced by shortened leukocyte telomere length (LTL), which could underlie this association. Shortened LTL reflects a cell's mitotic history

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The Euro50 is a proposed optical telescope with an equivalent aperture of 50 m. It will have a segmented primary mirror and full adaptive optics. To study the interaction of the telescope structure, the control system and the optics, an integrated simulation model has been formulated. The mechanical model is a modal version of an Ansys finite element model. The optics model is based on ray tracing