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The paper describes a novel method for self tuning cylinder pressure based heat release computation that is suitable for online usage in e.g. combustion phasing control applications. The method estimates the polytropic exponents and cylinder pressure offsets immediately preceding and succeeding the combustion event respectively using a fast nonlinear least squares method. The polytropic exponent a

Embedded systems are a characteristic but intangible part of an embedding environment. This poses a severe testing problem that gets further aggravated in embedded networks. The co-presence of hardware and software needs both behavioral and structural aspects to be covered, preferably by a single on-chip paradigm. The paper investigates the potential role of neural networks and introduces a Built-

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Popular Abstract in English Energy savings and climate change mitigation have been discussed in the world since the oil crisis in the 1970s and the building sector has been seen as one of the largest contributors to global warming effects in the world. Energy efficiency in buildings is a critical issue to be addressed in order to reduce electricity energy used in buildings and is one of the main tMozambique, situated in south-east Africa, has sub-tropical and tropical climate and plenty of natural resources for energy production. The country is however poor, and only about 25% of the population has access to electricity from the grid. A very large part of the energy used in the country is used in the residential sector, and there is a general lack of knowledge, regulations and tools concer

The Baltic Sea is one of many aquatic ecosystems that show long-term declines in dissolved silicate (DSi) concentrations due to anthropogenic alteration of the biogeochemical Si cycle. Reductions in DSi in aquatic ecosystems have been coupled to hydrological regulation reducing inputs, but also with eutrophication, although the relative significance of both processes remains unknown for the observ

Intermittent Parathyroid Hormone (PTH)((1-34)) has an established place in osteoporosis treatment, but also shows promising results in models of bone repair. Previous studies have been dominated by closed fracture models, where union is certain. One of the major clinical needs for anabolic therapies is the treatment of open and high energy fractures at risk of non-union. In the present study we th

Background: Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional indepen

BACKGROUND: Hemostatic disorders are common in obstetric complications. Thromboelastography (TEG (R)) simultaneously measures coagulation and fibrinolysis within 10 to 20 minutes. Our primary aim in this prospective longitudinal study was to obtain knowledge about physiological changes in TEG (R) variables during normal pregnancy and 8 weeks postpartum. The secondary aims were to compare TEG (R) v

In the present work we have selected a collection of statistical and mathematical tools useful for the exploration of multivariate data and we present them in a form that is meant to be particularly accessible to a classically trained mathematician. We give self contained and streamlined introductions to principal component analysis, multidimensional scaling and statistical hypothesis testing. Wit

Background Olaparib, a novel, orally active poly(ADP-ribose) polymerase (PARP) inhibitor, induced synthetic lethality in BRCA-deficient cells. A maximum tolerated dose and initial signal of efficacy in BRCA-deficient ovarian cancers have been reported. We therefore assessed the efficacy, safety, and tolerability of olaparib alone in women with BRCA1 or BRCA2 mutations and advanced breast cancer. M

BACKGROUND: Dietary factors are thought to have an important role in gastric and esophageal carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined the risks of gastric cancer and esophageal adenocarcinoma associated with meat consumption within the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort. METHODS: A total of 521,457 men and women

Abstract in Danish Formål: Formålet er at beskrive tuberkulosens (tbc.) epidemiologi i Danmark de sidste 25 år, specielt udviklingen i den danske befolkning. Metode: Et registerstudie af anmeldte tilfælde af tbc. i Danmark 1972-1996: Fra 1970-1989 i DIKE's register, fra 1990-1996 i EPI-registeret, epidemiologisk afd., Statens Serum Institut. Resultater: tbc.-incidensen faldt jævnt fra 1972 indtiThe present study is based on notified cases of tuberculosis (TB) in the National tbc. register 1972-1996. A decline in Tb incidence was seen from 1972 and until the mid-1980's. Subsequently the trend has reversed due to an increasing number of TB cases in foreigners. In 1996, 60% of all cases of TB in Denmark were found in foreigners reflecting the rising number of refugees and their families arr

This thesis treats different aspects of automotive control-systems and consists of four papers covering different areas in this large field. The first paper presents a 9-degrees-of-freedom dynamic model of a tractor-semitrailer vehicle, aimed at simulation and evaluation of active chassis-systems for stability enhancements. Special focus is put on inclusion of the dynamics of load transfer, which

Objective. Increasing survival of extremely low birth weight (ELBW; birth weight < 1000 g) infants raises a concern regarding the risks of adverse long-term outcome such as cognitive dysfunction. Few studies have reported long-term follow-up of representative regional cohorts. The objective of this study was to assess the 5-year outcome of a prospectively followed national ELBW infant cohort. Meth

Patients with acute asthma attending the emergency room were included in a double-blind, double-dummy and parallel group study to investigate whether a dry powder inhaler (Turbuhaler) can be used in acute asthma. If so, the aim was to establish the potency relationship between a beta 2-agonist (salbutamol) administered by the dry powder inhaler and the pressurized metered-dose inhaler (pMDI). Eigh

The topic of the thesis is codesign of flexible real-time control systems. Integrating control theory and real-time scheduling theory, it is possible to achieve higher resource utilization and better control performance. The integration requires new tools for analysis, design, and implementation. The problem of scheduling the individual parts of a control algorithm is studied. It is shown how sub