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BackgroundGraft-contaminating tumor cells correlate with inferior outcome in high-risk neuroblastoma patients undergoing hematopoietic stem cell transplantation and can contribute to relapse. Motivated by the potential therapeutic benefit of tumor cell removal as well as the high prognostic and diagnostic value of isolated circulating tumor cells from stem cell grafts, we established a label-free
When Diffusion Tensor Imaging (DTI) is used in clinical studies, statistical hypothesis testing is the standard approach to establish significant differences between groups, such as patients and healthy controls. However, diffusion tensors contain six degrees of freedom, and the most commonly used univariate tests reduce them to a single scalar, such as Fractional Anisotropy. Multivariate tests th
This chapter focuses on legal interpretation, reflecting on policy options between pluralism and harmonisation in two separate levels: (1) the desirability of establishing, or not, further harmonisation of interpretative rules, criteria and praxis in IP law; (2) whether internal harmonisation or systemic coherence between different areas of law and regulation that affect the same object or legal f
Background: Sports-related concussion (SRC) is increasingly recognized as a potential health problem in ice hockey. Quality of life (QoL) in players retiring due to SRC has not been thoroughly addressed. Materials & methods: QoL using the Sports Concussion Assessment Tool 5th Edition, Impact of Event Scale-Revised and Short Form Health Survey was measured in Swedish ice hockey players who reti
Background: Managing acute abdominal pain in the large and growing population of Roux-en-Y gastric bypass (RYGB)–operated patients poses a challenge to general surgeons, because of diagnostic limitations and the risk of internal herniation. Objective: To investigate the diagnoses, management, and outcome of RYGB patients admitted for acute abdominal pain. Setting: University Hospital, Sweden. Meth
The erection process of in situ cast concrete frameworks in multi-storey housing consists of multiple on site activities in which labour, equipment and materials are interacting in a complex system. Studies have shown that the current process involves a wide range of non-value adding activities, resulting in poor process efficiency. This paper presents a model developed for discrete-event simulati
Inflammation influences several steps of adult neurogenesis, but whether it regulates the functional integration of the new neurons is unknown. Here, we explored, using confocal microscopy and whole-cell patch-clamp recordings, whether a chronic inflammatory environment affects the morphological and electrophysiological properties of new dentate gyrus granule cells, labeled with a retroviral vecto
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To meet the demands of high electrical efficiencies in combination with low emissions for gas turbine-based power plants, wet cycles have gained new interest. The combustion chamber is a key component in such a power plant. Detailed investigations are necessary to gain insight into the formation of hazardous emissions such as CO and NOx. In this paper, computational fluid dynamics (CFD) has been e
The main topic of this PhD thesis is complexity reduction of linear time-invariant models. The complexity in such systems is measured by the number of differential equations forming the dynamical system. This number is called the order of the system. Order reduction is typically used as a tool to model complex systems, the simulation of which takes considerable time and/or has overwhelming memory
This is a study of wool in Icelandic history in a broad context, whereby wool production serves as a channel to central aspects of 18th-century society. The objective is to explore ideas about Iceland’s economy that were current in the 18th century in the light of developments in Denmark at the time, to place these ideas in the context of the recent introduction of workshopmanufacturing to Iceland
Famous for its many New Kingdom stelai and funerary shrines, Speos of Horemheb and magnificent quarries, this paper presents a preliminary report on a lesser acknowledged feature of Gebel el Silsila: its quarry marks. Focusing here on the northern section – Partition B – of Silsila East’s Main Quarry, seventeen individual quarry faces display totally 376 quarry marks, which have been divided into
The Dalby Gospel Book, dating from the eleventh century, is the oldest preserved complete manuscript with a medieval Scandinavian provenance, and has rightly been considered a document of great historical importance. Local patriotism has coloured its attribution by scholars to Dalby, with arguments presupposing judgemental quality assessments, questionable Anglo-Saxon parallells and alleged scriba
From a control design point of view, modern diesel engines are dynamic, nonlinear, MIMO systems. This paper presents a method to find low-complexity black-box dynamic models suitable for model predictive control (MPC) of NOx and soot emissions based on on-line emissions measurements. A four-input-five-output representation of the engine is considered, with fuel injection timing, fuel injection dur
A moral Historiography without Moralism. Critical views on modern Church History Efforts for realism without moral judgments have identified morals with present law. This leads to positivistic positions, where moral questions are being answered with references to historical legal situations only, without moral implications. With the political changes 1989–1990 a change in historiography followed.
Studiens syfte är att undersöka hur flöjtpedagoger yrkesverksamma på kulturskolor i Sverige beskriver sin undervisning med fokus på utveckling av det flöjtistiska hantverket hos nybörjare. Forskningsfrågorna som besvaras är: Vilket/vilka mål har flöjtpedagogerna med sin undervisning? Vilka flöjtistiska byggstenar anser flöjtpedagogerna vara nödvändiga att grundlägga hos nybörjarna? Hur arbetar flöThe aim of this study is to examine how flute teachers, working in the municipal Swedish music schools, describe the music education, focusing on the development of the beginner's technical skills of flute playing from a hermeneutic point of view. The research questions are: What are the flute teachers´ aims of their teaching? What basic skills of flute playing do they consider as important in
Water for firefighting is often associated with drinking water, due to fire hydrants. Fire hydrants have been installed in towns for a long time and are one of the most common ways for the rescue service to get hold of water for extinguishing fires. This report evaluates the ways that the rescue service uses their water and how the get continuously water to the fire site. Other extinguishing metho
The Scanian Economic-Demographic Database (SEDD) has been assembled by the Centre for Economic Demography (CED), Lund University. It contains information about the demographic and economic conditions of people that have lived in 5 parishes in Scania from the 17th century until the present. The SEDD database has been integrated with geographic data, which are digitized from four independent histori
