Sökresultat

Objectives To determine the incidence rate (IR) and predictors of myocardial infarction (MI) in patients with antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) as well as to estimate the IR ratio (IRR) of MI in AAV versus the background population. Methods 325 patients diagnosed with AAV 1997-2016 in Skåne, Sweden were included. Data were collected from the time of AAV dia

The objectives of this study were to explore active aging among people listed with an interest in relocation, and the relationships between active aging and aspects of perceived home. Using cross-sectional data from the 2022 RELOC-AGE project ( N  = 1,509, mean age = 70 years), linear regression analysis was conducted. Women and individuals with higher self-rated health and education reported hig

Heterogeneous integration of III-V narrow bandgap transistors on silicon technology is desirable for high frequency circuit implementations. Such high-speed transistors must, however, scale to large gate widths to be suitable for general circuit design. Averaging among many variable channels is a key challenge for nanowire devices. A simplified, but high-speed compatible, nanowire device process w

Three new cobalt complexes of the general formula [Co(II)(L)(CH3CN)]2+, where L is one of three pentadentate nitrogen-donor ligands based on the N4Py framework, have been synthesized and characterized. The capacity of the three complexes to effect photocatalytic proton reduction has been examined. Their photocatalytic activities in the presence of [Ru(bpy)3]2+, acting as a photosensitizer, and asc

Purpose: The purpose is to describe the Malmö Breast Tomosynthesis Screening Project from the beginning to where we are now, and thoughts for the future. Approach: In two acts, we describe the efforts made by our research group to improve breast cancer screening by introducing digital breast tomosynthesis (DBT), all the way from initial studies to a large prospective population-based screening tri

Operando resonant photoelectron spectroscopy (RPES) combined with modulated chemical excitation revealed the dynamic evolution of Ce3+/Ce4+ redox states at the surface of CeO2 during the CO oxidation reaction. Using alternating CO and O2 pulses as chemically modulated signals, we monitored the surface states in the valence band region, unveiling the evolution of electronic structure during the cat

We determined the 2025-2040 impact of climate and land use land cover change on streamflow in the Sironko catchment. LULCC was predicted using Cellular Automata Markov. The climate was statistically downscaled from the 29 GCMs of the IPCC Fifth Coupled Model Intercomparison Project using the delta method of the Agricultural Model Inter-comparison and Improvement Project under five climate regimes

Pd-Ga alloy nanoparticles with tunable compositions were produced by combining spark ablation with a downstream injection of a metal-organic precursor. This dual-process approach enables control over nanoparticle composition and morphology by adjusting precursor flow rate and sintering temperature. At lower precursor flows, uniform Pd-Ga nanoparticles form, exhibiting stable Pd5Ga2 and Pd2Ga phase

Purpose: To achieve the high sensitivity of digital breast tomosynthesis (DBT), a time-consuming reading is necessary. However, synthetic mammography (SM) images, equivalent to digital mammography (DM), can be generated from DBT images. SM is faster to read and might be sufficient in many cases. We investigate using artificial intelligence (AI) to stratify examinations into reading of either SM or

By combining the quantitative advantage of laser absorption spectroscopy and the superior spatiotemporal resolution of high-speed microscopic imaging, we report, for the first time, the transient aluminum monoxide (AlO) concentration distribution around a burning micro-sized aluminum droplet in water-vapor-rich ambient. Arrangement of two lasers at resonant and non-resonant wavelengths, respective

OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy

Apolipoprotein E4 (ApoE4), the major genetic risk factor for Alzheimer's disease (AD), is vital for understanding cellular processes involved in AD pathogenesis. Evidence implicates endosomes as a central player in AD, where endosomal enlargement in neurons is among the earliest changes in AD. This enlargement was reported to be enhanced in APOE4 carriers. Cells internalize ApoE into endosomes for

Single cell sequencing technologies (scRNA-seq, scATAC-seq, etc.) have revolutionized the study of complex tissues and unique organisms, providing researchers with a much needed species agnostic tool to study biological processes at the cellular level. To date, scRNA-seq technologies are expensive, require sufficient cell quantities, and need biological replicates to avoid batch effects or artifac

Proper arterial versus venous endothelial lineage identity is required to establish a hierarchical network of arteries and veins and prevent the occurrence of life-threatening arteriovenous malformations. The molecular mechanisms that govern arteriovenous lineage specification remain however incompletely understood. Here, we demonstrate that the transcription factor Prdm16 is expressed in arterial

The Iberian ribbed newt (Pleurodeles waltl) constitutes a central model for probing the basis of vertebrate regeneration. Here, we present the sequencing and chromosome-scale assembly of the 20.3Gb P. waltl genome, which exhibits the highest level of contiguity and completeness among giant genome assemblies. We uncover that DNA transposable elements are the major contributors to its expansion, wit

This paper examines how the concept ‘nature-positive’ as a means to enhance biodiversity is defined and used, viewed through the lens of power. Building on a three-dimensional conceptualization of power, we elaborate on i) how ‘nature-positive’ enters and remains on business and policy agendas, ii) different interpretations from both ecological and business perspectives, and iii) the governance of

III-Nitride high-electron mobility transistors (HEMTs) grown on AlN substrates offer significant advantages for high-power, high-frequency applications due to AlN high thermal conductivity and ultra-wide bandgap. However, achieving high-quality thin GaN channel layers on AlN is challenging because of lattice mismatch, which leads to columnar growth. In this work, we present the development of a tw

Objective: To determine bone shape changes over two years after acute anterior cruciate ligament (ACL) injury and to compare knees treated with ACL reconstruction (ACLR) vs no ACLR. Design: We used prospective data involving 129 young adults (46 ​% female, mean age 25 years) with recent ACL injury from a subcohort within the prospective multicenter NACOX study. Patients were treated according to S

BACKGROUND: The predictive value of atrial conduction abnormalities, reflected by P-wave indices (PWI), and their association with biomarkers signaling fibrosis for the development of atrial fibrillation (AF) in patients with heart failure (HF) remains underexplored.OBJECTIVE: We aim to investigate the associations between PWI, fibrosis biomarkers, and the risk of incident AF in patients with HF.M