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The manipulation and focusing of submicron/nanometre-scale objects are becoming increasingly important in the fields of biology, chemistry, and materials science. Acoustofluidics provides for the high throughput and precise manipulation of cells and particles with simple equipment. However, application to submicron/nanoparticles is challenging due to the particle volume dependence of the acoustic
The pancreatic islet is a highly structured micro-organ that produces insulin in response to rising blood glucose. Here we develop a label-free and automatic imaging approach to visualize the islets in situ in diabetic rodents by the synchrotron radiation X-ray phase-contrast microtomography (SRμCT) at the ID17 station of the European Synchrotron Radiation Facility. The large-size images (3.2 mm ×
Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in vaccination, autoimmunity, and cancer. Here, we use fate mapping, functional analyses, and comparative cross-species transcriptomics to show that RORγt+ DCs are a co
Objectives: To assess amide proton transfer weighted (APTw) MR imaging capabilities in differentiating high-grade glial tumors across alpha-thalassemia/mental retardation X-linked (ATRX) expression, tumor-suppressor protein p53 expression (p53), O6-methylguanine-DNA methyltransferase promoter (MGMTp) methylation, isocitrate dehydrogenase (IDH) status, and proliferation marker Ki-67 (Ki-67 index)
We present a wall-to-wall map of dominant tree species in Swedish forests accompanied by pixel-level uncertainty estimates. The tree species classification is based on spatiotemporal metrics derived from Sentinel-1 and Sentinel-2 satellite data, combined with field observations from the Swedish National Forest Inventory and auxiliary data on geomorphometry and canopy height. We apply an extreme g
Transcription factor cooperation is essential for specifying the heterogeneous dendritic cell (DC) lineages that orchestrate adaptive immunity, yet how it drives subset diversification remains poorly understood. Here, we employed a sequential anchored screen of 70 transcription factors using direct cellular reprogramming to identify regulators that specify type 2 conventional DCs (cDC2s) and plasm
Chronic obstructive pulmonary disease (COPD) is commonly caused from smoking cigarettes that induce biological stress responses. Previously we found disorganized endoplasmic reticulum (ER) in fibroblasts from COPD with different responses to chemical stressors compared to healthy subjects. Here, we aimed to investigate differences in stress-related gene expressions within lung cells from COPD and
Natural killer (NK) cells represent the cytotoxic member within the innate lymphoid cell (ILC) family that are important against viral infections and cancer. Although the NK cell emergence from hematopoietic stem and progenitor cells through multiple intermediate stages and the underlying regulatory gene network has been extensively studied in mice, this process is not well characterized in humans
Osteoarthritis is one of the most common musculoskeletal diseases and increases the risk of severe cardiovascular disease, like heart attack and stroke. In some individuals, osteoarthritis and cardiovascular disease will co-occur. This co-occurrence might be due to shared risk factors, for example high age, lifestyle factors and/or a shared genetic liability for the two diseases. Here, we show tha
Controlling the streaming flow in acoustically actuated microchannels enables the targeted motion of suspended micro-objects. This can offer novel approaches for rare cell studies or cell sorting in medicine or basic biology. In this work, we utilize the temperature dependence of the acoustic body force, which originates from the interaction of an acoustic field with gradients in compressibility o
1 Quousque tandem abutere UTVÄRDERING, RAPPORT 2015:275 Att genomföra ett självständigt arbete vid Lunds universitet -studenters perspektiv ola holmström | Lunds Universitet Kvalitet och Utvärdering Lunds universitet Box 117 221 00 Lund Tel. vx: 046-222 00 00 Tel: 046-222 70 45 Fax: 046-222 40 07 ISBN 978-91-7623-521-8 (Serien Utvärdering Rapporter är en fortsättning av serien Utvärderingsenheten
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/sjalvstandiga_arbeten_vid_lu.pdf - 2026-07-22
Microsoft Word - thesis final doc 10 des 98 version 2000.doc Hördur V. Haraldsson Is ecological living in Sweden different from conventional living? i Is ecological living in Sweden different from conventional living? -A case study of the ecological village Toarp and the conventional town Oxie in south Sweden Master’s thesis December 1998 By Hörður V. Haraldsson Supervisors: Janusz Niemczynowicz,
https://www.lumes.lu.se/sites/lumes.lu.se/files/haraldsson_hordur.pdf - 2026-07-22
Farmers’ Knowledge and Perception towards the Sustainable Adoption of Sugar Beet in Kenya LUND UNIVERSITY International Master’s Programme in Environmental Science Farmers’ Knowledge and Perception towards a Sustainable Adoption of Sugar Beet in Kenya A Thesis Submitted in Partial Fulfillment for the Award of a Master of Science Degree in Environmental Science at Lund University, Sweden Author: Su
https://www.lumes.lu.se/sites/lumes.lu.se/files/sosu_edward.pdf - 2026-07-22
Uppsatsmall IMPLEMENTERINGEN AV ARBETSREHABILITERING ENLIGT IPS- MODELLEN I ETT VÅRDTEAM FÖR NYINSJUKNADE I PSYKOS – EN ÖVERSIKTLIG RAPPORT Ulrika Bejerholm & Helene Hillborg 2 Copyright: Ulrika Bejerholm, professor i psykiatrisk hälso- och sjukvårdsforskning, Lunds universitet; Helene Hillborg, doktor i handikappvetenskap, Lunds universitet; 2016 Form och design: Anna K Blomgren, 2016 3 Förord Vi
https://www.cepi.lu.se/sites/cepi.lu.se/files/cepi_misa_midhagen_rapport_.pdf - 2026-07-22
Aberrantly expressed cytokines in the bone marrow (BM) niche are increasingly recognized as critical mediators of survival and expansion of leukemic stem cells. To identify regulators of primitive chronic myeloid leukemia (CML) cells, we performed a high-content cytokine screen using primary CD34+ CD38low chronic phase CML cells. Out of the 313 unique human cytokines evaluated, 11 were found to ex
α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has several physiologically relevant properties, including binding of heme and radicals as well as enzymatic reduction, that are used in the protection of cells and tissue. Research has revealed that A1M can ameliorate heme and ROS-induced injuries in cell cultures, organs, explants and animal models. Recently, i
As cardio metabolic disease manifestations tend to cluster in families there is a need to better understand the underlying mechanisms in order to further develop preventive strategies. In fact, genetic markers used in genetic risk scores, important as they are, will not be able alone to explain these family clusters. Therefore, the search goes on for the so called missing heritability to better ex
A 27-year-old woman (gravida 2, para 1) was transported to the regional university hospital in gestational week (GW) 34 + 4 due to a three-day history of fever, abdominal pain and reduced foetal movements. She had developed a dry cough one day prior to the admission (Figure S1). The woman, was slightly overweight (BMI 27 kg/m2 ) but otherwise healthy. She had normal antenatal check-ups and an obst
