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Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

Cultured Mast Cells from Patients with Asthma and Controls Respond with Similar Sensitivity to Recombinant Der P2-Induced, IgE-Mediated Activation

The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with asthma and healthy controls under identical conditions. Mast cells were cultured from peripheral blood from twelve patients with an objectively confir

Uttorkning av träregelväggar efter översvämning

Klimatförändringarna med stigande havsnivåer gör att förutsättningarna för vårt byggande måste förändras i kustnära områden. Länsstyrelsen i Skåne har fattat ett beslut om att mark under +3 meter över havet döms ut för bebyggelse. Kommunerna vid kusten får då mycket svårt att expandera, och vill därför kunna hitta eventuella lösningar för att kunna bygga i utsatta lägen. En möjlig lösning är att aWith the climate change sea levels are rising which changes the boundary conditions for sites along the coast. The County Administrative Board of Skåne has decided that new buildings should be built at least 3 meters above sea level. Because of this decision the coastal municipalities have problems with expanding further, and are really keen on finding alternative solutions in order to allow build

Children´s Rights in Education : Experiences from 16 countries in Global South during 18 years as researchers and teachers

The aim of this report book in Sociology of Law, and Child Rights Institute, Lund University, is to gather, sum up and report, in a summarizing overview in an introduction followed by three concluding articles, our main experiences as researchers and teachers after 2016.That year, 2016, the English version of the Sida-funded international training program, Child Rights, Classroom and School Manage