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2021-06-01 Call for proposals for research funding in BECC for the years 2021-2022 BECC (Biodiversity and Ecosystem Services in a Changing Climate) welcomes proposals for research funding within the vision and aims of BECC. This is a joint call between Lund university (LU) (up to 7 million SEK) and University of Gothenburg (UGOT) (up to 2 million SEK) and aims at a continued consolidation of the c
Course evaluation for GEON04 2015 report For 2015, it was the fourth time the Master course GEON04 was taught. This year the student group was smaller, 7 students. The statics for the course are shown below, and in this summary only general comments are made. All involved teachers have received the full report, including comments on each lecture. The involved teachers were asked to reflect upon th
https://www.geology.lu.se/sites/geology.lu.se/files/geon04_course_evaluation_2015.pdf - 2026-05-28
Background Olaparib, a novel, orally active poly(ADP-ribose) polymerase (PARP) inhibitor, induced synthetic lethality in BRCA-deficient cells. A maximum tolerated dose and initial signal of efficacy in BRCA-deficient ovarian cancers have been reported. We therefore assessed the efficacy, safety, and tolerability of olaparib alone in women with BRCA1 or BRCA2 mutations and advanced breast cancer. M
Att förutsäga framtiden – modellering som ett verktyg för att förutsäga vattenkvantitet och vattenkvalitet Inom 100 år så kommer klimatet förändrats avsevärt om utsläpp av växthusgaser fortsätter i samma takt som idag. Detta kommer påverka temperatur, nederbörd vilka i sin tur påverkar flödet av vatten i Sverige. Ett avrinningsområde består av olika jordtyper, vegetation och topografi, vilka allClimate change will alter the hydrological cycle in the 21st century with implications for the water balance and water quality. As characteristics of the landscape may vary significantly between nearby locations, hydrological models need to be able to delineate responses attributed to specific landscape characteristics, to estimate their responses to altered climatic drivers. Small streams are the
The Baltic Sea is one of many aquatic ecosystems that show long-term declines in dissolved silicate (DSi) concentrations due to anthropogenic alteration of the biogeochemical Si cycle. Reductions in DSi in aquatic ecosystems have been coupled to hydrological regulation reducing inputs, but also with eutrophication, although the relative significance of both processes remains unknown for the observ
The aim of this thesis was to elucidate developments in epidemiology, clinical manifestations and complications in Chlamydia trachomatis (C.trachomatis) and Mycoplasma genitalium (M.genitalium) infection. In study I the frequencies of non-gonococcal salpingitis, gonococcal salpingitis and ectopic pregnancy (EP) were observed over a period of 28 years and correlated to the prevalence of Neisseria g
The increase and range extension of wolves (Canis lupus L) and brown bears ( Ursus arctos L) in Scandinavia inevitably impacts moose (Alces alces L.) populations and, as a consequence, the size and composition of the hunter harvest must be adjusted. We used a sex- and age-structured moose population model to delineate optimal harvest strategies under predation and to compare the resulting harvest
1. In a correlative study, we investigated the relative importance of fish predation, refuge availability and resource supply in determining the abundance and size distributions of the introduced and omnivorous signal crayfish (Pacifastacus leniusculus) in lakes and streams. Moreover, the biomass and food selection of predatory fish was estimated in each habitat type and stable isotopes of carbon
Background: Although omic-based discovery approaches can provide powerful tools for biomarker identification, several reservations have been raised regarding the clinical applicability of gene expression studies, such as their prohibitive cost. However, the limited availability of antibodies is a key barrier to the development of a lower cost alternative, namely a discrete collection of immunohist
The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). (I and II) Autoantibodies to the C3 cleaving enzyme complex of the alternative pathway, C3 nephritic facto
Katalysatorer påskyndar en reaktion utan att själva förbrukas; denna mening känner nog många igen från sin skoltid. Andra har hört talas om katalysatorer som något de "har i bilen". Mycket riktigt är det främst i bilar där vi i våra vardagliga liv stöter på katalysatorer. Här används de för att omvandla de mycket giftiga gaserna kolmonoxid och kväveoxid till för människorna ofarligt kvävIn order to fully understand the underlying processes of catalysis, it is vital to combine measurements of the catalyst surface, where the reaction occurs, with measurements of the gas concentration close to the catalyst. We have developed a convenient setup, which uses a single laser system to visualise the gas surrounding a working catalyst in situ at realistic operating conditions. Planar Lase
Purpose: To assess the additional value of subtraction ictal single-photon emission computed tomography (SPECT) coregistered to MRI (SISCOM) for localization of the epileptogenic zone in patients with drug-resistant epilepsy scheduled for invasive video-EEG (VEEG) before epilepsy surgery by a descriptive study from clinical practice. Methods: Forty-nine consecutive epilepsy patients between Januar
Background: The aim of this study was to examine in elderly men a relationship between depressive symptoms, peripheral vascular disease and cerebral blood flow (CBF). Methods: Population-based cohort study started with an examination of 809 men at age 55, followed by the first (age 68ys) and second follow up (age 82ys). 128 survivors were examined at age 82 with Tc-99m-HMPAO-SPECT to estimate CBF,
Our aims were to characterize familial hypercholesterolemia (FH) in a Swedish FH population and to further elucidate the clinical expression and treatment response in relation to genotype. Secondly, we wanted to identify gene variants, which may have impact on cholesterol levels in apparently healthy subjects. In the search for sequence alterations in the large LDL receptor gene we introduced and
Apart from the substantive public procurement rules, harmonising national provisions for the award of public contracts, the Community also strives to ensure compliance with those rules. For that purposes the Remedies Directive 89/665/EEC has been adopted to ensure that effective and rapid remedies are available to aggrieved bidders. This directive has recently been amended by Directive 2007/66/EC
The regulation of the European parliament and the Council (EG) nr. 864/2007 on the law applicable to non-contractual obligations is known as Rome II. Rome II contains a conflict rule in art. 7 which determines the law applicable to a claim involving environmental damages connected with more than one state. This conflict rule does not only apply to cases of damage to property and persons, but also
Background: Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional indepen
OBJECTIVES: The predictive ability of the STarT Back Tool (SBT) has not yet been examined among acute/subacute back and/or neck pain in a primary care setting in respect to health-related quality of life (HRQoL) and work ability outcomes. The aim of this study was to evaluate the SBT's predictive validity for HRQoL and work ability outcomes at long-term follow-up in a population with acute/subacut
Abstract: Cardiovascular diseases and diabetes mellitus are closely linked by sharing common risk factors, such as obesity, insulin resistance, hypertension and dyslipidaemia. These intermediate risk factors are affected by the joint effects of environment and genetics. Although a multitude of studies aimed to disentangle the effects of gene-environment interactions, many of the published gene-en
