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Sleeping-related distress in a palliative care population : A national, prospective, consecutive cohort

Background: Sleep, a multi-dimensional experience, is essential for optimal physical and mental wellbeing. Poor sleep is associated with worse wellbeing but data are scarce from multi-site studies on sleeping-related distress in palliative care populations. Aim: To evaluate patient-reported distress related to sleep and explore key demographic and symptom distress related to pain, breathing or fat

De hjälper oss till rätta : normaliseringsarbete, självbestämmande och människor med psykisk utvecklingsstörning

For people with learning disabilities care in institutions has been replaced by a life in community settings e.g. group homes, where a number of persons (4-5) are living with staff support. My case-studies cover three elderly and three more lately produced such units as well as a ward in a nursing home. Data were gathered through participant observations and semistructured interviews with staff an

Association between time interval from neoadjuvant chemoradiotherapy to surgery and complete histological tumor response in esophageal and gastroesophageal junction cancer : a national cohort study

The optimal time interval from neoadjuvant therapy to surgery in the treatment of esophageal cancer is not known. The aim of this study was to investigate if a prolonged interval between completed neoadjuvant chemoradiotherapy and surgery was associated with improved histological response rates and survival in a population-based national register cohort. The population-based cohort study included

Investigating the mechanical characteristics of bone-metal implant interface using in situ synchrotron tomographic imaging

Long-term stability of endosseous implants depends on successful bone formation, ingrowth and adaptation to the implant. Specifically, it will define the mechanical properties of the newly formed bone-implant interface. 3D imaging during mechanical loading tests (in situ loading) can improve the understanding of the local processes leading to bone damage and failure. In this study, titanium screws

Geophysical Induced Polarisation (IP) laboratory measurements on E. coli-sand mixtures

The aim of the MIRACHL project is the characterisation and monitoring of in-situ remediation of chlorinated hydrocarbon contamination using an interdisciplinary approach and geophysical methods, such as DCIP (direct current induced polarisation) to investigate the remediation process. To interpret these geophysical field IP data, lab investigations with different kinds of bacteria are necessary to

Risk factors for seroma formation after axillary lymph node dissection with special focus on the impact of early shoulder exercise

Background: Shoulder and arm dysfunction such as reduced range of motion (ROM) and seroma formation, are common complications following axillary lymph node dissection (ALND). There are conflicting results on the effect of early postoperative exercise on the risk of seroma. This study aims to present incidence of symptomatic seroma formation in a large, population-based cohort, and assesses whether

Vertical III-V nanowire tunnel field-effect transistors : a circuit perspective

The energy scaling of integrated circuits has reached its limit because the operating voltage of Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFET) based switches has reached its minimum value. MOSFETs are limited by thermionic emission and cannot achieve a subthreshold swing (SS) below 60 mV/decade at room temperature. Tunnel Field-Effect Transistors (TFET), which operate on field modula

Lexical transfer in second- and third language early vocabulary acquisition

Comparing lexical transfer in second- and third language early vocabulary acquisition The present study compared 30 functional English monolinguals and 30 highly proficient (CEFR C1+) Swedish–English bilinguals. They acquired vocabulary in a pseudo-language derived from typologically unrelated Finnish. None of the participants had productive proficiency in Finnish although for societal reasons the

An exploratory open-label multicentre phase I/II trial evaluating the safety and efficacy of postnatal or prenatal and postnatal administration of allogeneic expanded fetal mesenchymal stem cells for the treatment of severe osteogenesis imperfecta in infants and fetuses: the BOOSTB4 trial protocol

Introduction Severe osteogenesis imperfecta (OI) is a debilitating disease with no cure or sufficiently effective treatment. Mesenchymal stem cells (MSCs) have good safety profile, show promising effects and can form bone. The Boost Brittle Bones Before Birth (BOOSTB4) trial evaluates administration of allogeneic expanded human first trimester fetal liver MSCs (BOOST cells) for OI type 3 or severe

Oleogels as controlled delivery systems for probiotics

A new encapsulation strategy for probiotics is highly needed to tackle the challenge of significant viability loss of bacteria during storage and passage through the gastrointestinal system. A new controlled delivery system for probiotics based on EC oleogels is proposed in this thesis. A relatively non-complicated in vitro lipolysis model was established to evaluate the relative conversion from t

Multicentric Use of Commercially Available Infrarenal Endografts During Fenestrated Endovascular Aortic Repair : A Feasibility Study

Purpose: This study aimed to assess the feasibility and short-term outcomes of different manufactured proximal and distal stent graft components during fenestrated endovascular aortic repair (FEVAR). Materials and methods: A multicenter retrospective review was conducted at 3 aortic centers, involving all consecutive patients who underwent FEVAR utilizing a customized Dacron-based tubular proximal

To give or not give antibiotic prophylaxis for planned caesarean section : An assessment of risk of postpartum prescription of antibiotics depending on prophylaxis regimen

Introduction: No national recommendation for antibiotic prophylaxis for planned caesarean section in Sweden exists. Swedish delivery units have chosen different strategies. Some units routinely administer antibiotic prophylaxis to all women for whom a caesarean section is planned, while other units give prophylactic antibiotics to risk groups only. We took advantage of this “natural experiment” to

Long-term follow-up of the randomized, prospective Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE) trial

Background: Early substitution of calcineurin inhibitor (CNI) with mammalian target of rapamycin inhibitors has been shown to improve kidney function and reduce intimal hyperplasia in heart transplant (HTx) recipients but data on long-term outcome of such a regime are still sparse. Methods: In the SCHEDULE trial, 115 de novo HTx recipients were randomized to (1) everolimus with reduced exposure of

Mapping trait versus species turnover reveals spatiotemporal variation in functional redundancy and network robustness in a plant-pollinator community

Functional overlap among species (redundancy) is considered important in shaping competitive and mutualistic interactions that determine how communities respond to environmental change. Most studies view functional redundancy as static, yet traits within species—which ultimately shape functional redundancy—can vary over seasonal or spatial gradients. We therefore have limited understanding of how

Ledarskap i socialt arbete - En studie av efterfrågade variabler vid rekrytering av ledare på mellannivå

Authors: Karin Lindsjö and Johanna Rydiander Title: Leadership in social work: A study of requested variables regarded middle level leaders during recruitment [translated title] Supervisor: Kristina Göransson Assessor: Staffan Blomberg Although working as a leader at middle level within social work is an interesting research area with its complex nature, there is not much science regarding this f

Can the Act on System of Choice Empower Women? An interview study of female entrepreneurs' experiences on the Swedish homecare market

When the Act on System of choice was implemented on the Swedish homecare market in 2009, there seemed to be an assumed understanding that by increasing competition on the eldercare market through privatization it would create better opportunities for women. Entrepreneurship was phrased as a solution for empowering and emancipating women in breaking out from a fixed role in low-status professions.

Targeting SphK2 in hypertension-induced neurodegeneration

Does treating high blood pressure improve neurodegeneration High blood pressure, also called hypertension could damage the brain. Our research tries to understand how lowering blood pressure affects the hypertensive brain. Hypertension is the disease that people have abnormally high blood pressure. Nowadays, 1 in 5 people worldwide have hypertension, accounting for 1.13 billion people. This cause

Stepping Down Fatigued or Not: What Makes Flight Crews Decide to Step Down From Duty.

With the emergence of industrialisation, the work-life balance has become a point of discussion in many industries, among which the aviation industry. Distortions in the work-life balance became especially apparent when 24/7 economies evolved, and industries made a transition to facilitate and serve these economies. Incidents and accident have since then been related to fatigue more than before. T

Kriminalteknisk bevisning och kriminalteknikerns roll i brottmålsprocessen

The increasingly frequent use of forensic evidence in the prosecution of criminal cases should in the long run result in increased analysis of its effectiveness. To date, such analysis has been limited, most probably due to rights of parties to use forensic evidence to support their respective arguments in cases and the rights of the courts to assess and rely on such evidence in criminal cases. Pr