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Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding

Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou

Prospective observational study of tofacitinib in ulcerative colitis - analysis of clinical data, fatigue and health-related quality of life during the induction phase

BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and

Utvc21 ht 2017 schedule 2017-09-29

BIDS UTVC21 Lectures and seminars 2017 (Updated 2017-09-29) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Course Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Allen et al

https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_ht_2017_schedule_2017-09-29.pdf - 2026-04-23

Slutrapport LU Land Horizon Scan 2020

Microsoft Word - Bilaga 1_Detaljerad metodbeskrivning_JD.docx Samverkan för en hållbar markanvändning – vilka utmaningar behöver lösas? En systematisk framtidsspaning inom ramen för samverkansinitiativet LU Land Huvudförfattare: Maria von Post, Juliana Dänhardt och Henrik G. Smith Medförfattare: Cecilia Akselsson, Johanna Alkan Olsson, Emily Boyd, Sara Brogaard, Pål Börjesson, Yann Clough, Johan E

https://www.luland.lu.se/sites/luland.lu.se/files/2021-11/Slutrapport%20LU%20Land%20Horizon%20scan_2020.pdf - 2026-04-23

Årscykel bisyssla

Sektionen HR har tagit fram ett universitetsgemensamt stöd i form av en årscykel för bisyssla. Genväg:Ta del av årshjulets olika steg i löptext Årscykelns olika stegJanuariUppstart årlig anmälningsskyldighet för lärare – under första kvartalet.Information till prefekter och lärare om att bisyssla ska anmälas senast 31 mars. Hantering av anmälningar och eventuella beslut om upphörande av bisyssla.F

https://www.hr-webben.lu.se/arscykel-bisyssla - 2026-04-21

LTH_2014.book

LTH_2014.book 1 Innehåll Gemensamma föreskrifter och information läsåret 2014/15 ..........................2 Arkitektutbildning ..........................................................................................6 Brandingenjörsutbildning .............................................................................12 Civilingenjörsutbildning i bioteknik ......................................

https://www.lth.se/fileadmin/lth/anstallda/utbildningsadministration/studiehandbok/SHB_2014-15.pdf - 2026-04-21

Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility.

Dysfunction in various parts of immune defence, such as immune response, immune complex clearance, and inflammation, has an impact on pathogenesis in systemic lupus erythematosus (SLE). We hypothesised that combinations of common variants of genes involved in these immune functions are associated with susceptibility to SLE. The following variants were analysed: HLA DR3, HLA DQ2, C4AQ0, Fcgamma rec

Vårterminen 2024

Här hittar du som är student eller medarbetare hos oss information om valbara kurser, kalendarium för hela terminen. JanuaryWeek 3: 15-21 January15.1    Official start of spring semester15.1     MFAAR meeting 10.00-11.0015.1     Meeting with the exchange students 11.00-11.3015.1    ALL STUDENTS 12.00-13.00 Student forum with lunch WELCOME TO NEW SEMESTER 19.1    Application portal BFA and MFA prog

https://www.khm.lu.se/varterminen-2024 - 2026-04-21

Relationship of the Hormone-Sensitive Lipase-Mediated Modulation of Cholesterol Metabolism in Individual Compartments of the Testis to Serum Pituitary Hormone and Testosterone Concentrations in a Seasonal Breeder, the Mink (Mustela vison).

The role of cholesterol differs in the two compartments of the testis. In the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. Here we evaluate the hormone-sensitive lipase (HSL) modulation of the cholesterol metabolism in each compartmen

Assessing the spatial variability in peak season CO2 exchange characteristics across the Arctic tundra using a light response curve parameterization

This paper aims to assess the spatial variability in the response of CO2 exchange to irradiance across the Arctic tundra during peak season using light response curve (LRC) parameters. This investigation allows us to better understand the future response of Arctic tundra under climatic change. Peak season data were collected during different years (between 1998 and 2010) using the micrometeorologi

Expression, activity, and subcellular localization of testicular hormone-sensitive lipase during postnatal development in the guinea pig

The present work reports on testicular hormone-sensitive lipase (HSL), the biological significance of which has been documented in male fertility. The HSL protein levels and enzymatic activity were measured, respectively, by densitometry of immunoreactive bands in Western blots, performed with antibodies against recombinant rat HSL, and by spectrophotometry in seminiferous tubules (STf) and inters

Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G

Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the

Nyhetsbrev Från GÅS-projektet Mars 2025

Nyhetsbrev från GÅS-projektet mars 2025 Professor Sölve Elmståhl har ordet Temat för detta nyhetsbrev är nya forskningsfynd i GÅS-studien. Show as web page I detta nyhetsbrev berättar vi om aktuella forskningsfrågor och resultat som utgår ifrån insamlade data från GÅS- projektet.  Fler projekt rör riskfaktorer för vanliga kroniska sjukdomar som nedsatt njur- och lungfunktion, högt blodtryck och på

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2025-10/Nyhetsbrev%20fra%CC%8An%20GA%CC%8AS-projektet%20mars%202025.pdf - 2026-04-23

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Stomstabilisering av prefabricerade betonghus - Fördelning av vindlaster till stabiliserande väggar LTH Ingenjörshögskolan vid Campus Helsingborg Institutionen för byggvetenskaper/ Avdelningen för byggnadskonstruktion Examensarbete: Linn Adolfsson Lina Carlsson  Copyright Linn Adolfsson, Lina Carlsson LTH Ingenjörshögskolan vid Campus Helsingborg Lunds universitet Box 882 251 08 Helsingborg LTH S

https://www.byggmek.lth.se/fileadmin/byggnadskonstruktion/publications/THID/adolfsson_carlsson.pdf - 2026-04-21