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Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel
This master thesis work was performed in collaboration with BioGaia AB, a Swedish biotech- company producing probiotic supplements containing the bacteria Limosilactobacillus reuteri. The products provided by BioGaia contain live microorganisms. Therefore, a method suitable for the correct enumeration of living cells is crucial in probiotic samples and today the so-called plate count method is use
Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N-acetylcysteine (NAC). The inflammatory mediator, h
Background: IgE-mediated allergy is associated with immunoglobulin heavy constant G chain (Fcγ) (GM) genes (IGHG) on chromosome 14q32.3. Investigation of the alternative GM allotypes of γ3, γ1 and γ2 chains has disclosed new structural and functional IgG subclasses and B-cell variants, with possible effects on childhood asthma. Objective: To investigate different IGHG (GM) gene complexes in a
This article provides an overview of the findings from the Information Systems (IS) Well-Being Project that was started in the fall of 2020. There were two goals of this project: 1) to understand the physical, mental, social, and financial well-being of IS academics during the COVID-19 pandemic, and 2) to theorize the downstream effects of the pandemic on the health of the IS research ecosystem. T
Prekonceptionell hälsa och rådgivning Kvinnor och mäns levnadsvanor inför graviditet påverkar fostret och det blivande barnets hälsa. Under våren 2019 ges en utbildning i Prekonceptionell hälsa och rådgivning vid Lunds universitet. Utbildningen är den första kursen i Sverige inom prekonceptionell hälsa, vilket gör den unik i sitt slag. Den riktar sig till barnmorskor generellt, och i synnerhet til
https://www.medicin.lu.se/sites/medicin.lu.se/files/prekonceptionell_halsa_20181218.pdf - 2026-07-15
Throughout five chapters, the thesis deals with the issues of international humanitarian and human rights law arising out of the practice of punitive house demolition, that is repetitively utilized in the Occupied Palestinian Territories by the Israeli authorities, in response to the acts of insurgency/terrorism. The first chapter (Introduction) enables the reader to get a glimpse of the precise o
