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Objective: To update and expand upon prior Osteoarthritis Research Society International (OARSI) guidelines by developing patient-focused treatment recommendations for individuals with Knee, Hip, and Polyarticular osteoarthritis (OA) that are derived from expert consensus and based on objective review of high-quality meta-analytic data. Methods: We sought evidence for 60 unique interventions. A sy
Forest Canopy Height (FCH) is one of the key variables for understanding forest structure distribution and growth. Remotely sensed data such as the NASA Ice, Cloud and Land Elevation Satellite-2 (ICESat-2) ATL08 provides accurate FCH measurements; however, its point-based nature limits spatial continuity. This study addresses the challenge by generating a continuous FCH map over the West Usambara
Horizontal gene transfer (HGT) is a major driver of evolution and a key source of innovation in the microbial world. Mobile genetic elements (MGEs), such as plasmids and phages, often act as agents of HGT or as vehicles for cargo genes, some of which define the adaptive potential of the host organism in specific environments. These genes are involved in immunity, anti-immunity, virulence, and anti
This thesis creates multiple indices to score and rank developing countries with regard to their suitability for engaging in debt-for-climate swaps, and thus identify the most suitable country candidates. The origin of debt-for-climate swaps lies in the 1980s, and after a period of diminished use and attention they have become a topic of discussion again, especially in the last two years. Desp
We study the Coulomb chain where particles are restricted to one dimension and experience three-dimensional Coulomb interactions with their nearest and next-to-nearest neighbours. The distances between consecutive particles are treated as random variables. It is shown that the correlation between clusters of consecutive variables decay exponentially with the number of variables separating them. Th
This thesis examines how female-targeting fintech firms can internationalize in ways that genuinely promote financial inclusion for women. Conducted as an exploratory interview study with Female Invest, it builds on the broader observation that gender remains largely absent from fintech’s outlook. The study addresses two key research gaps. First, financial inclusion efforts often overlook how cult
Machine Protection Systems (MPS) at the European Spallation Source (ESS) aim to protect equipment from damage while minimizing accelerator downtime with respect to safety and availability requirements. Main Control Room operators and MPS experts rely on alarm systems to effectively detect faults and guide intervention actions. Current implementations in the Fast Beam Interlock System (FBIS) are pr
I use the full count data of census year 1910 to examine the intermarriage determinants in Swedish immigrants and the consequences to those who were married to natives compared to their counterparts in endogamy. The results from intermarriage determinants were in line with prior research in general. The results showed that immigrants in exogamy with natives wouldn’t have a high probability o
This thesis aims to address the complex legal challenges related to the responsibility of multinational corporations for human rights violations and environmental harm in global supply chains. Starting from the context of increasing pressure on transnational businesses and the shortcomings of soft law instruments such as the UN Guiding Principles and the OECD Guidelines, the study examines the pot
The Azerbaijani city of Shusha stands out as an exemplary place for reconstruction based on the principles of sustainable development in the post-conflict era. This research examines the city of Shusha’s aim of building a sustainable city model from scratch and focuses on two major directions: the transition to solar-based systems in the city’s energy supply and the establishment of a clean transp
Wind damage is one of the most economically and ecologically significant natural disturbances in European forests, yet the cloud cover that follows major storms routinely blocks optical satellite acquisitions for weeks, precisely when rapid damage mapping is most valuable. Synthetic aperture radar (SAR) circumvents this limitation through all-weather imaging, but pixel-level windthrow detection fr
Synthesis of molecularly imprinted polymer microspheres using precipitation polymerization was first reported in 1999 in Lund. The synthetic approach attracted great interest for molecular imprinters worldwide due to its simplicity. Following the initial demonstration of feasibility for material synthesis, imprinted polymer microspheres were found to exhibit good colloidal stability qualifying for
To further understand the inter-relationship of the familial transmission of major depression (MD) and alcohol use disorder (AUD), we examine, via a multivariable Cox proportional hazards model, risks for AUD and MD in 1,244,516 individuals born in Sweden from 1970 to 1990 to intact mother-father pairs as a function of parental diagnoses of MD and/or AUD. Across the nine possible mating types, we
Marketing is an important function and practice in everyday business. It involves getting potential customers interested in a product or service through value-oriented arguments. In this way, marketing plays a pivotal role in driving the consumption of goods and services. Given the increasing consumption of goods and services, decreasing product lifetimes, and increasing levels of waste in all pro
The field of biomedicine is constantly investing significant research efforts in order to gain a more in-depth understanding of the mechanisms that govern the function of body compartments and to develop creative solutions for the repair and regeneration of damaged tissues. The main overall goal is to develop relatively simple systems that are able to mimic naturally occurring constructs and can t
This commentary discusses the role of increasingly artificial intelligence-infused big tech platforms in facilitating and normalising high-emission lifestyles and consumption practices. It introduces the notion of algorithmically facilitated emissions to initiate a shift from a logic of ‘climate collapse by design’ to a logic of ‘emissions reduction by design’. Reducing consumption-based emissions
The unification of quantum mechanics and general relativity has long been elusive. Only recently have empirical predictions of various possible theories of quantum gravity been put to test, where a clear signal of quantum properties of gravity is still missing. The dawn of multi-messenger high-energy astrophysics has been tremendously beneficial, as it allows us to study particles with much higher
A central challenge in linguistics pertains to understanding how the polished, static form of a written text emerges from the messy, moment-by-moment decisions of the writer. While the structures of finished texts have been extensively theorized, and the real-time cognitive processes of writing have been widely studied, the relationship between these real-time processes and the functional linguist
