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This paper describes the several phases which led, from the conceptual design, prototyping, construction and tests with beam, to the installation and operation of the BRAN (Beam RAte of Neutrals) relative luminosity monitors for the LHC. The detectors have been operating since 2009 to contribute, optimize and maintain the accelerator performance in the two high luminosity interaction regions (IR),

Doctoral education in medicine, engineering, technology and science (METS) is in many ways different from doctoral education in the humanities or social sciences. In the METS disciplines, typically, students and supervisors work and publish together within the supervisors’ research projects. The projects are usually financed by the supervisors’ research grants and their success, in terms of high q

Background: Severity of the primary unilateral cleft lip/nose deformity (UCL/N) is postulated to play a key role in postoperative complications, aesthetic result, and need for secondary surgery. There is no validated and widely accepted classification scheme of initial cleft severity. The purpose of this study was to validate the Unilateral Cleft Lip Cleft Severity Index as a reliable tool for eva

Massive parallel sequencing (MPS) is increasingly used for human identification purposes in forensic DNA laboratories. Forensic DNA samples are by nature heterogeneous and of varying quality, both concerning DNA integrity and matrices, creating a need for assays that can handle low amounts of DNA as well as impurities. Commercial short tandem repeat (STR) analysis kits for capillary electrophoresi

Lifetime measurements are presented for the ls2p3P1, 2 levels for He-like C V and N VI. From the measured lifetimes, transition probabilities are deduced for both allowed and spin-forbidden transitions. The values for the 1s23S0-1s2p3P1 transition rates, 0.29 × 108 and 1.38 × 108 s-1 for C V and N VI respectively, are found to be in good agreement with theory.

The orbit and physical parameters of the previously unsolved double-lined eclipsing binary Tyc 5227-1023-1, discovered during the search for RR Lyr variable candidate members of the Aquarius stream, are derived using high-resolution chelle spectroscopy and V, i' photometry. A synthetic spectral analysis of both components has been performed, yielding metallicity [M/H] =-0.63± 0.11 for both stars a

The asymmetric formal hydroamination of enamines using a CuH catalyst is reported. The method provides a straightforward and efficient approach to the synthesis of chiral 1,2-dialkyl amines in good yields with high levels of enantioselectivities for a broad range of substrates, and should have significant value for the preparation of molecules bearing a 1,2-diamine motif.

The value of a statistical life (VSL) is a widely used measure for the value of mortality risk reduction. As VSL should reflect preferences and attitudes to risk, there are reasons to believe that it varies depending on the type of risk involved. It has been argued that cancer should be considered a "dread disease," which supports the use of a "cancer premium." The objective of this study is to in

Dysfunction of the gastrointestinal tract has now been recognized to affect all stages of Parkinson's disease (PD). The consequences lead to problems with absorption of oral medication, erratic treatment response, as well as silent aspiration, which is one of the key risk factors in developing pneumonia. The issue is further complicated by other gut abnormalities, such as small intestinal bacteria

Emboldened by the aesthetic,- emotional-, and corporeal turns in the study of world politics, International Relations (IR) scholars are increasingly paying attention to the political dimension of affects and emotions. Yet while, so far, affect and emotions have been studied as (micro-political) forces that circulate between bodies in the context of the everyday, little attention has been given to

Objective: To update and expand upon prior Osteoarthritis Research Society International (OARSI) guidelines by developing patient-focused treatment recommendations for individuals with Knee, Hip, and Polyarticular osteoarthritis (OA) that are derived from expert consensus and based on objective review of high-quality meta-analytic data. Methods: We sought evidence for 60 unique interventions. A sy

INTRODUCTION: Idiopathic Parkinson's disease (PD) is a progressive neurodegenerative disorder related to α-synuclein misfolding and aggregation. For this reason, it belongs to the family of 'synucleinopathies', which also includes some other neurological diseases. Although imaging and ancillary investigations may be helpful in the diagnostic workup, the diagnosis of PD mostly relies on the clinici

The purpose of this paper is to understand the relationship between the formal (governance established in law) and informal institutions (governance not established in law) that underpin the planning, operation and improvement of local and regional public transport, by using case studies of four countries: Britain (more specifically England, outside London); the Netherlands; Germany; and Sweden. T