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BACKGROUND: Resection is the cornerstone of curative treatment for many nonmetastatic gastric cancers (GCs), but the population treatment patterns remains largely unknown. This large international population-based study aimed at investigating the treatment patterns and trends for nonmetastatic GC in Europe and the United States and at exploring factors associated with resection.METHODS: Data of pa

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The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects. The international COVID19-NMR consortium seeks to provide such new approaches by gathering scientific expertise worldwide. In particular, making available viral proteins and RNAs will pave th

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Argonauts of industry: Knowledge gathering and technologies in use in Sweden’s industrial breakthroughIn this article we explore how knowledge transfer about industrial production and new technologies affected Sweden’s rapid industrialisation in the second half of the nineteenth century. Focusing on two case studies taken from the Swedish glass and gunpowder industries, we argue for the importance

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Background: Most family studies on venous thromboembolism (VTE) have focused on first-degree relatives. Objectives: We took a pedigree-based approach and examined the risk of VTE and cardiometabolic disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods: From the Swedish population, we identified a total of 482 185 pedigrees containing a mean of 14.2

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Over the last 10,000 y, humans have manipulated fallow deer populations with varying outcomes. Persian fallow deer (Dama mesopotamica) are now endangered. European fallow deer (Dama dama) are globally widespread and are simultaneously considered wild, domestic, endangered, invasive and are even the national animal of Barbuda and Antigua. Despite their close association with people, there is no con

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COVID-19 was first identified in Wuhan City in December 2019 and spread throughout Hubei Province and other parts of China. After causing significant morbidity and mortality in China, by February 2020, it had spread to numerous other countries, infecting millions of people and causing a large number of deaths across the world. The COVID-19 pandemic put a burden on almost all areas of the world inc

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Environmental change is disrupting mutualisms between organisms worldwide. Reported declines in insect populations and changes in pollinator community compositions in response to land use and other environmental drivers have put the spotlight on the need to conserve pollinators. While this is often motivated by their role in supporting crop yields, the role of pollinators for reproduction and resu

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Urbanization is a major contributor to biodiversity declines. However, studies assessing effects of urban landscapes per se (i.e., disentangled from focal habitat effects) on biodiversity across spatial scales are lacking. Understanding such scale-dependent effects is fundamental to preserve habitats along an urbanization gradient in a way that maximizes overall biodiversity. We investigated the i

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Land sharing versus land sparing describes contrasting strategies to conserve biodiversity while maintaining agricultural production. We comprehensively reviewed empirical studies comparing land-sharing and land-sparing strategies to assess how these were conceptualized and how consequences for biodiver- sity, commodity production, and additional ecosystem services have been quantified. Out of 52

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INTRODUCTION: Climate change is one of the 21st century's biggest public health issues and health care contributes up to 10% of the emissions of greenhouse gases in developed countries. About 15 million laparoscopic procedures are performed annually worldwide and single-use medical equipment is increasingly used during these procedures. Little is known about costs and environmental footprint of th

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This article explores the burgeoning Nepalese hip-hop scene – commonly known as nep-hop – as a discursive intervention in the post-war politics of Nepal. Its core argument is that nep-hop oftentimes demonstrates an ethos of peacebuilding through popular culture. Indeed, many songs explicitly criticize violence, war, and the political leaders who recently brought the nation to a civil war. Yet, thi

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Prostate-specific antigen (PSA) is a serine protease secreted by hath normal prostate glandular celts and prostate cancer cells. The major proteolytic substrates for PSA are the gel-forming proteins in semen, semenogelin (Sg) I and II. On the basis of the PSA cleavage map for Sg I and II, a series of small peptides (ie., ≤ 7 amino acids) was synthesized and coupled at the COOH terminus to 7-amino-

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Introduction: Etiological diagnosis of neurocognitive disorders of middle-old age relies on biomarkers, although evidence for their rational use is incomplete. A European task force is defining a diagnostic workflow where expert experience fills evidence gaps for biomarker validity and prioritization. We report methodology and preliminary results. Methods: Using a Delphi consensus method supported

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This article presents the investigation of two linen shirts which form part of the funerary dress of Bishop Peder Pedersen Winstrup (1605–1679), buried 1680 in Lund Cathedral, southern Sweden. When the grave was opened in 2013, it was discovered that the body had been naturally mummified, and that the funerary dress, including the linen, was well-preserved. Extant Early Modern linen garments are r

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Background: Previous research suggests that interactions between preschool teachers and children in early care and educational contexts can contribute to the child’s positive attachment development and socioemotional adjustment. Objective: Investigate how the transition process to preschool is organized and whether various ways of organizing it may differently influence family–teacher relationship

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The great variety of earth's microorganisms and their functions are attributed to the heterogeneity of their habitats, but our understanding of the impact of this heterogeneity on microbes is limited at the microscale. In this study, we tested how a gradient of spatial habitat complexity in the form of fractal mazes influenced the growth, substrate degradation, and interactions of the bacterial st