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The amyloid β-protein (Aβ) is believed to play a central role in Alzheimer’s disease (AD) pathogenesis and there is great interest in understanding the process of Aβ aggregation, its underlying mechanism and the species generated during aggregation and their biological activity. Although Aβ has been studied for more than 30 years, analysis of its aggregation has been hampered by structural and che

Emergency management requires precise and reliable information about the current situation of emergency, existing sources and facilities, while more than 80% of this information has spatial component or location. Considering the urgent and time sensitive nature of emergency situations, it is necessary to collect and use spatial information of the current state of the emergency within the minimum w

Air quality data assimilation aims to find a best estimate of the control parameters (see theory chapter) for those processes of the atmosphere which govern the chemical evolution of biologically relevant height levels, typically located in the the lowermost atmosphere. As in data assimilation (see theory chapters), we have to resort to numerical models to complement usually sparse observation net

Fluctuation relations are powerful equalities that hold far from equilibrium. However, the standard approach to include measurement and feedback schemes may become inapplicable in certain situations, including continuous measurements, precise measurements of continuous variables, and feedback induced irreversibility. Here we overcome these shortcomings by providing a recipe for producing detailed

In this article, we experimentally demonstrate a way of controlling the group velocity of an optical pulse by using a combination of spectral hole burning, the slow-light effect, and the linear Stark effect in a rare-earth-ion-doped crystal. The group velocity can be changed continuously by a factor of 20 without significant pulse distortion or absorption of the pulse energy. With a similar techni

The small-disturbance electro-mechanical dynamics of a power system can be translated to an equivalent circuit model with inductances and capacitances. Damping control of active power in proportion to local frequency as with a VSC-HVDC link or an energy storage then corresponds to introducing a resistor in the circuit model. This letter shows that impedance matching can be used to select resistor

Methods for simple and fast detection and differentiation of bacterial species are required, for instance, in medicine, water quality monitoring, and the food industry. Here, we have developed a novel label array method for the counting and differentiation of bacterial species. This method is based on the nonspecific interactions of multiple unstable lanthanide chelates and selected chemicals with

Desulfurization at medium temperature was investigated with focus on impacts of temperature and CO2 concentration under Oxyfuel firing and Regenerative Calcium Cycle (RCC) conditions. Investigation started with thermodynamic analysis and ThermoGravimetric Analysis (TGA). Tests were then conducted by a bench-scale fixed-bed type reactor, using a synthetic gas mixture. Various parameters were evalua

Under appropriate conditions, neural tissues transplanted into the adult mammalian brain can survive, integrate, and function so as to influence the behavior of the host, opening the prospect of repairing neuronal damage, and alleviating symptoms associated with neuronal injury or neurodegenerative disease. Alternative mechanisms of action have been postulated: nonspecific effects of surgery; neur

• Transforming present production and consumption systems towards Circular Economy will require that new models for value provision are devised by companies and accepted by consumers• Numerous factors drive companies towards initiating the shift to more circular material flows• Businesses also face many barriers on their way towards circular business models• There is opportunity space to collectiv

This dissertation deals with design and characterization of functional structures for scattering of electromagnetic waves. An abundance of these structures can be found in nature, such as the structural coloration in the feathers of a peacock, the scales of butterflies and the shell of scarab beetles. Human design of structures providing specific interactions with electromagnetic waves have a long

Disease-modifying treatments remain an unmet medical need in Parkinson's disease (PD). Such treatments can be operationally defined as interventions that slow down the clinical evolution to advanced disease milestones. A treatment may achieve this outcome by either inhibiting primary neurodegenerative events ("neuroprotection") or boosting compensatory and regenerative mechanisms in the brain ("ne

The objective of the present study is the investigation of possibilities for boosting peptide antiinflammatory effects by tryptophan end-tagging, including identification of underlying mechanisms for this. In doing so, effects of tryptophan end-tagging of KYE21 (KYEITTIHNLFRKLTHRLFRR), a peptide derived from heparin co-factor II, on membrane and lipopolysaccharide (LPS) interactions were investiga

The UNESCO Post-2015 Development Agenda proposes equitable quality education and lifelong learning for all as its overarching goals for education. A holistic quality approach is espoused to encourage lifelong learning and thereby build inclusive, sustainable, and prosperous societies. Their quality goals are particularly ambitious given that the practical recommendations for inclusive education ne

In 1977 WHO published in the Bulletin a Memorandum on Methods for the Detection of Haemophilia Carriers. This was produced following a WHO/WFH (World Federation of Haemophilia) Meeting of Investigators in Geneva in November 1976, and has served as a valuable reference article on the genetics of haemophilia. The analyses discussed were based on phenotypic assessment, which, at that time, was the on

This chapter explores the ultrasonic additive manufacturing (UAM) advanced solid-state metal additive/subtractive manufacturing process that combines ultrasonic welding and computer numerical control milling to fabricate solid metal components, layer-by-layer, from metal foils. The chapter will discuss the three key abilities of UAM: complicated geometries, dissimilar material bonding, and object

The impedance bandwidth of a small antenna is a critical design parameter. In the present paper, we present stored energies which can be used as a tool to predict the largest possible bandwidth for antenna designs within a given region. These predictions are given in terms of the best possible Q-factor that can be attained within the region. The here presented energies are valid for structures tha