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Hypertension is considered the major modifiable risk factor for the development of cognitive impairment. Because increased blood pressure is often accompanied by an activation of the immune system, the concept of neuro-inflammation gained increasing attention in the field of hypertension-associated neurodegeneration. Particularly, hypertension-associated elevated circulating T-lymphocyte populatio

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The development of business ecosystems in smart cities is currently hampered by the absence of established approaches for facilitating long-term value and sustainability. In our view, the underlying reason is the lack of collective action involving various organizations in the design process. Collective action for the good of the whole ecosystem does not take place in existing participatory practi

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Although microfinance is often thought of as a tool to address poverty in developing countries, it is also being introduced in a number of countries in the developed world. The paper presents a qualitative study of the first year of the introduction of microfinance to address vulnerable groups in Sweden. Savings banks and nonprofit organisations collaborated in the introduction of microfinance as

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Geophysical methods provide important information for mapping the subsurface. In semiarid areas, a detailed knowledge of the aquifers geometry can assist to a better management of groundwater. In the Valle Alto (Bolivia), which is a semiarid region, there is gap in the knowledge about the aquifer system geometry and hydrogeological processes. Local reports indicated problems in some wells such as

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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of TNF inhibitors in comparison with placebo and other treatment strategies in adult patients affected by psoriatic arthritis.

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During the COVID-19 pandemic, we are likely to see a significant increase in the requests for rapid assessment of cardiac function, due to the frequent pre-existence of cardiac pathologies in patients admitted to hospital, and to the emergence of specific cardiac manifestations of this infection, such as myocarditis, sepsis related cardiomyopathy, stress induced cardiomyopathy and acute coronary s

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Due to its reported high sampling frequency and precision, the Tobii Pro Spectrum is of potential interest to researchers who want to study small eye movements during fixation. We test how suitable the Tobii Pro Spectrum is for research on microsaccades by computing data-quality measures and common properties of microsaccades and comparing these to the currently most used system in this field: the

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Rhodothermus marinus has the potential to be well suited for biorefineries, as an aerobic thermophile that produces thermostable enzymes and is able to utilize polysaccharides from different 2nd and 3rd generation biomass. The bacterium produces valuable chemicals such as carotenoids. However, the native carotenoids are not established for industrial production and R. marinus needs to be genetical

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This study aims to reveal the obstacles to achieving quality in distance learning during the Coronavirus (COVID-19) pandemic and was based on a large sample of professors and students of universities in the Arab world (Algerian, Egyptian, Palestinian, and Iraqi). The primary aim of this research was to investigate the various ways in which students pursued their studies at home during the universi

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Purpose: The European Union Driver License Committee recently developed a questionnaire as a screening tool for obstructive sleep apnea (OSA) named the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers. We sought to address the reliability of the Turkish version of this questionnaire. Methods: The EUROSAS was translated into Turkish. Using a “test-retest approach”, dat

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This paper presents a novel methodology to in-vivo estimate the elastic constants of a constitutive model proposed to characterize the mechanical behavior of the breast tissues. An iterative search algorithm based on genetic heuristics was constructed to in-vivo estimate these parameters using only medical images, thus avoiding invasive measurements of the mechanical response of the breast tissues

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The serum metabolome contains a plethora of biomarkers and causative agents of various diseases, some of which are endogenously produced and some that have been taken up from the environment1. The origins of specific compounds are known, including metabolites that are highly heritable2,3, or those that are influenced by the gut microbiome4, by lifestyle choices such as smoking5, or by diet6. Howev

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How can anthropologists negotiate access in high-profile, bureaucratic apparatuses, such as a UN human rights monitoring mechanism – and what can a detailed account of these negotiations tell us of such apparatuses, their operational dynamics and the processes through which they exert an impact, broadly construed? This article addresses these questions through the notion of tactical subjectivity b

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This chapter presents the theory of ecologically unequal exchange (EUE). The theory explains asymmetric transfers of non-monetary, biophysical resources and environmental harms between different countries or regions. The chapter provides a cursory review of the literature on methods for empirically identifying such asymmetries and testing hypotheses derived from the theory. To identify EUE require

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Nano-ceramic particles can serve as reinforcing agents for metallic materials to improve their mechanical properties. However, it is important to ensure chemical compatibility between the matrix and particles. In the present study, magnesium composites with and without nano-hydroxyapatite (nHA) particles were fabricated for bone reconstruction applications. Two different techniques were used, Conv

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For all involved in astronomy, the importance of monitoring and determining astrophysical magnetic-field strengths is clear. It is also a well-known fact that the corona magnetic fields play an important part in the origin of solar flares and the variations of space weather. However, after many years of solar corona studies, there is still no direct and continuous way to measure and monitor the so

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A microcalorimetric vessel for monitoring the initial phases of cytotoxic reactions in the micro-submicrowatt region has been designed and tested. The vessel is intended to be used witha multichannel microcalorimetric system from Thermometric, Järfälla, Sweden and can be built up stepwise in a modular way. The different functions of perfusion, stirring and addition of small amounts of soluble immu

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This is a protocol for a Cochrane Review (Overview). The objectives are as follows:. The aim of this study is to evaluate the benefits and harms of different interventions used in the management of TTN of the newborn.