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Stupidity is generally thought of as a hindrance to learning: an epistemic vice that stands in the way of knowledge and understanding. In this article, I challenge this idea by exploring some of the meanings of stupidity that place it in a positive relation to learning. In this light, the article discusses two notions of stupidity: stupidity as unfinished thought and stupefaction through study. I
Poststructuralist perspectives need to be reconciled with political economic readings of urban globalization. One approach complements the other: the enactment of distantiated circuits and the territorialization of flows occur within existing geographies of uneven development while contingently reproducing or reshaping such spatial conditions of possibility. We argue that broadening the realm of c
In this study, we investigate the molecular structural characteristics of organic remains in various cellular organelles from a 180 Ma Jurassic royal fern belonging to the Osmundaceae family of ferns, and compare their carbon isotopic compositions to a now-living species of royal fern (Osmunda regalis). We discovered molecular structural va
The role of raw plantain flour (RPF) and its citric acid (CA)-esterified counterpart (EPF) on the carbohydrate nutritional properties of cookies was investigated. Cookies were elaborated with commercial wheat flour (CWF), RPF, EPF, or a CWF-EPF blend, and assessed for composition, starch digestibility, texture and sensory properties. EPF-cookie showed the lowest digestible starch (DS) content and
Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy. Early diagnosis may allow initiation of treatment before irreversible damage has occurred. However, diagnosis is commonly delayed well into adulthood because of the nonspecific character of initial symptoms. Here, we report findings in a neonate who was evaluated because of a positive family history of OAT defici
A search for the electroweak production of charginos and sleptons decaying into final states with two electrons or muons is presented. The analysis is based on 139 fb- 1 of proton–proton collisions recorded by the ATLAS detector at the Large Hadron Collider at s=13 TeV. Three R-parity-conserving scenarios where the lightest neutralino is the lightest supersymmetric particle are considered: the pro
This protocol describes the design and use of CRISPRi-mediated transcriptional silencing in human iPSCs, for loss-of-function studies in brain development research. The protocol avoids single cell selection, thereby eliminating side effects of clonal expansion and sites of viral integration. We also describe a neural progenitor differentiation protocol and discuss the challenges of target-specific
A Poisson integral formula for a weighted Laplacian in the unit disc Beskrivning: In this paper a counterpart of the classical Poisson integral formula is found for a weighted Laplace differential operator in the unit disc. In the process the corresponding Dirichlet boundary value problem is solved for arbitrary continuous boundary data. The associated power series expansions are calculated and in
The logistics concepts at BMW's engine factory in Munich are continuously revised, in order to optimise the logistics process. The objective of this thesis work is to study if it would be profitable to use an individual, reusable package for transporting and handling engine wiring harnesses in order to prevent damages. Approach The work was divided into different stages. First the flow of th
Climate change is considered to be among the most serious threats to the sustainability of the world's environment, the health and well being of its people and the global economy. The rising levels of greenhouse gases in the global atmosphere are expected to cause a rise in global temperatures. In Kyoto, December 1997, the Kyoto Protocol was written under which industrialised countries have ad
Abstract Title: The video surveillance industry in the USA - the future development and the technology shift Seminar date: 4/6 - 2010 Course: FEKP01, Degree Project Graduate Level, Business Administration, Graduate Level, 15 University Credit Points (ECTS-cr) Authors: Johan Lindgren and Marc Palm Mentor: Thomas Kalling Key words: Technology shift, Video surveillance industry, Organizational Learni
This report describes the methodology for performing a quantitative risk analysis for a unidirectional road tunnel. By using representative accident scenarios, a basic queue model and performing an evacuation analysis the amount of casualties for each scenario can be estimated. By using the described methodology it gives the decision-makers a good idea of the risk level in the tunnel. The results
Recent spinal cord literature abounds with descriptions of genetic preprogramming and the molecular control of circuit formation. In this paper, we explore to what extent circuit formation based on learning rather than preprogramming could explain the selective formation of the monosynaptic projections between muscle spindle primary afferents and homonymous motoneurons. We adjusted the initially r
The use of molecular data to study the evolutionary history of organisms has revolutionized the field of systematics. Now with the appearance of high throughput sequencing (HTS) technologies, more and more genetic sequence data are available. One of the important sources of genetic data for phylogenetic analyses has been mitochondrial DNA. The limitations of mitochondrial DNA for the study of phyl
Objectives: The primary objective was to investigate the utility of blood-basedbiomarkers of amyloid, tau, and neurodegeneration for (i) screening, (ii)enrichment, and (iii) tracking response to treatment in clinical trials of Alzheimer’sdisease.Methods: Longitudinal, participant-level data used in these studies was drawn fromthe Swedish BioFINDER study and the ADNI study. Participants were classi
This paper presents a two-stage procedure to create a surface integrity predictor. The first stage includes data clustering, which allows to evaluate the achievable surface quality. The second stage consists in training the model to predict which cluster the machined surface will belong to. To demonstrate the applicability, an experimental plan for machining of Inconel 718 in milling was developed
Herein, we present KiMoPack, an analysis tool for the kinetic modeling of transient spectroscopic data. KiMoPack enables a state-of-the-art analysis routine including data preprocessing and standard fitting (global analysis), as well as fitting of complex (target) kinetic models, interactive viewing of (fit) results, and multiexperiment analysis via user accessible functions and a graphical user i
