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Activation of the contact system has two classical consequences: initiation of the intrinsic pathway of coagulation, and cleavage of high molecular weight kininogen (HK) leading to the release of bradykinin, a potent proinflammatory peptide. In human plasma, activation of the contact system at the surface of significant bacterial pathogens was found to result in further HK processing and bacterial

The ribosome and tRNA levels of Escherichia coli cells, transformed with a native or mutated Vitreoscilla hemoglobin genes (vhb), were investigated using asymmetrical flow field-flow fractionation (AFFFF). Mutagenesis of vhb by error-prone PCR was carried out to alter the growth behavior of microaerobically cultivated native VHb-expressing E. coli. A VHb mutant, pVMT1, was identified, which was ab

Several interactions of cytokines with extracellular matrix molecules are mediated by proteoglycans, such as biglycan and decorin. Using surface plasmon resonance, we show for the first time that tumour necrosis factor-alpha (TNF-alpha) binds to both biglycan and decorin with K(d)s of 0.81 microM and 1.23 microM respectively, a binding that was confirmed by Scatchard plots using a solid phase assa

The nucleotide sequences of the variable region genes encoding five different human, high affinity antibodies, specific for the major neutralization determinant (AD-1) expressed by human cytomegalovirus glycoprotein B (gp58/116), have been determined. Three of the five heavy chain variable regions belonged to the small VHV-family, although they combined with a diverse set of light chains (V kappa

Popular Abstract in Swedish Boken handlar om jag-begreppet i tanke och tal. Huvudfrågan är vad vi menar när vi säger 'jag. Relaterade frågor rör vilka sorters jag-kunskap och självmedvetande som behövs för att kunna tala om sig själv. Betoningen ligger på menings- och referensteorier, men ett stort utrymme ägnas även åt jag-tankar och jagbegreppets roll för tänkande i allmänhet.The subjct of this book is the first person in thought and language. The main question is what we mean when we say 'I'. Related to it are questions about what kinds of self-consciousness and self-knowledge are needed in order for us to have the capacity to talk about ourselves. The emphasis is on theories of meaning and reference for 'I', but a fair amount of space is devoted to 'I'-thoughts and t

PurposeThe aim of the study is to understand how meaning is assigned to online searching by viewing it as a mundane, yet often invisible, activity of everyday life and an integrated part of various social practices.Design/methodology/approachSearching is investigated with a sociomaterial approach with a starting point in information searching as entangled across practices and material arrangements

The ultrastructure of the chromatophores of two decapod crustaceans, Crangon crangon and Pandalus borealis, is investigated. The pigment appears macroscopically as small units, so-called chromatosomes. These contain separate chromatophores of different colors, and each color is composed of several chromatophores. Each chromatophore contains pigment granules, tubuli (ca. 210 Å), a network of cister

The present work is a continuation of the morphological studies of the nauplius eye and frontal organs of the Crustacea. The previous papers on this topic comprised the Decapoda (ELOFSSON, 1963) and the Malacostraca (ELOFSSON, 1965). Its has been found that the nauplius eye and frontal organs of the Crustacea are separated into four different types. These comprise the Phyl-lopoda, Anostraca, Maxil

The Zvejnieki burial ground in northern Latvia is one of the largest concentrations of burials from the Mesolithic and Neolithic in Northern Europe. The 308 burials, dominated by primary inhumation, excavated in the 1960s and 1970s have become important references for understanding the hunter-gatherer mortuary practices in the region. Recent excavations, implementing a taphonomy-focused archaeotha

The paper analyses the hegemony of the growth paradigm through the example of its naturalisation in capitalist production and consumption relations. Applying a combination of theoretical elements from the Marxian tradition, the Regulation approach and Bourdieusian sociology, emphasis is placed on how the growth imperative is reflected in people’s minds and bodies. It becomes hegemonic because it a

The influence of different dryer fabrics on the contact coefficient has been studied experimentally under various conditions. A bench-scale drying apparatus, in which the fabric could be fixed at variable tensions, was used in the experiments. A technique for measuring the heat flux and surface temperatures of the paper sample and the hot surface was developed. Three paper grades were used in the