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Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. Methods: This was a longitudinal cohort study using d
Objectives: We aimed to map the correlation between thermoluminescent dosimeters (TLDs) and Gafchromic film for measuring absorbed doses and to compare minimum, maximum, and mean absorbed doses over larger regions of interest and at various craniofacial organs and tissues during cone beam computed tomography (CBCT) exposure of the mandibular third molar region. Study Design: We positioned TLDs at
The problem of finding maximum (or minimum) witnesses of the Boolean product of two Boolean matrices (MW for short) has a number of important applications, in particular the all-pairs lowest common ancestor (LCA) problem in directed acyclic graphs (dags). The best known upper time-bound on the MW problem for n × n Boolean matrices of the form O(n2.575) has not been substantially improved since 200
To complete a new Swedish railway line in a much shorter timeframe than today, alter natives to the traditional methods need to be explored. One option is the use of prefabricated concrete slabs elevated on piers, analogous to the concept used in China for building new railways in record time (He et al., 2017). The method has the advantage of directly tackling the barrier effects exhibited by trad
This paper focuses on how one can relate management thinking/practices to entrepreneurial processes in the context of formal organization. In order to do this we develop a number of related 'spatial concepts' providing us with the possibility of describing entrepreneurship as a 'creation and use of space for play/innovation'. Using concepts of space, the managerial and the entrepreneurial dimensio
Accident models and analysis methods affect what accident investigators look for, which contributory factors are found, and which recommendations are issued. This paper contrasts the Sequentially Timed Events Plotting (STEP) method and the Functional Resonance Analysis Method (FRAM) for accident analysis and modelling. The main issue addressed in this paper is the comparison of the established mul
A bilinear system model of a continuous tank reactor from a biotechnology application (F. Mandenius et al., 1987) is studied. The concentrations of the substrate sugar and the product ethanol were measured on-line and utilized to control the flow-rate through the fermenter. The system can be integrated analytically making it possible to describe the reachable sets. Limited controllability is found
The direct problem of time dependent electromagnetic scattering in the dispersive sphere is solved by a wave splitting technique. The electric field is expanded in a series involving vector spherical harmonics, leading to a system of wave equations for each term. These systems are reduced to scalar wave equations for each term, which are solved via reflection operators. Some preliminary numerical
Using the optical double resonance and level crossing methods, properties of several excited S , P , and D states in 39 K were studied. The S and D states were populated using stepwise excitation with the first P state as an intermediate level. An rf lamp and a CW dye laser were used in the first and second excitation steps, respectively. The studied P states were populated in the cascade decay of
Nonlinear propagation of electromagnetic waves is an important problem in optics. Often the properties of the nonlinear media are not fully understood. The solution of an inverse problem can provide an aid to that understanding. An inverse transmission problem is posed, it is one of reconstructing the medium parameters, by measurement of a wave that has been propagated through the nonlinear medium
This paper studies regional museum, archives and arts education commissions of the Region of Scania, reformed in 2009, from a policy analysis perspective. It describes the background, design and implementation of the new policy and analyses its effects. The paper gives detailed information on the complexities of policy tool design and implementation, and discusses it in the light of regional gover
The aim of this study is to systematically compare parametric and non-parametric techniques for analyzing trends in annual NDVI derived from NOAA AVHRR sensor in order to examine how trend type and departure from normality assumptions affect the accuracy of detecting long-term change. To generate annual data, the mean NDVI of a four-month long ‘green’ season was computed for fifteen sites (located
