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Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

Stem cell transplantation can improve behavioral recovery after stroke in animal models but whether stem cell-derived neurons become functionally integrated into stroke-injured brain circuitry is poorly understood. Here we show that intracortically grafted human induced pluripotent stem (iPS) cell-derived cortical neurons send widespread axonal projections to both hemispheres of rats with ischemic

5-year mental health and eating pattern outcomes following bariatric surgery in adolescents : a prospective cohort study

Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra

Patient choice, entry, and the quality of primary care : Evidence from Swedish reforms

Policies aiming to spur quality competition among health care providers are ubiquitous, but their impact on quality is ex ante ambiguous, and credible empirical evidence is lacking in many contexts. This study contributes to the sparse literature on competition and primary care quality by examining recent competition enhancing reforms in Sweden. The reforms aimed to stimulate patient choice and en

Older persons' experiences with wearable sensor-based fall risk screening in free-living conditions - a qualitative study

BACKGROUND: Falls are common among older persons and can have a major impact on their lives. Wearable sensors used in free-living conditions (moving naturally in one's daily living environment) can be used to predict falls and fall risks. To understand if using the wearable sensors is an acceptable way for older persons to be screened for fall risks, it is important to have knowledge of older pers

Shear force capacity of cross laminated timber beams : Numerical investigations of fracture behaviour

This paper deals with numerical investigations of cross laminated timber (CLT) beams. Previous investigations have revealed discrepancies between experimental test results and suggested design methods regarding shear force capacity of such beams. To gain further understanding of the failure behaviour and the shear force capacity, nonlinear finite element analyses have been performed, using a cohes

Risk of Stroke in Patients With Atrial Fibrillation Is Associated With Stroke in Siblings : A Nationwide Study

Background: It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. Methods and Results: In this nationwide study of the Swedish population, patients with AF and t

Revisiting Public Support for the Euro, 1999–2017 : Accounting for the Crisis and the Recovery

This article explores the evolution and determinants of public support for the euro since its creation in 1999 until the end of 2017, thereby covering the pre-crisis experience of the euro, the crisis years and the recent recovery. Using uniquely large macro and micro databases and applying up-to-date econometric techniques, the authors revisit the growing literature on public support for the euro

Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Background: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential confound

No title

Vi ser en förändring i relationen mellan det samtida individualiserade jaget och en ny typ av emotionell marknadsföring. Genom att undersöka det svenska rakhyvel-företaget Estrids Instagramflöde och image tar vi reda på om och hur dessa kan tänkas genomsyras av denna emotionella cool-kapitalism. Med hjälp av teorier grundade i postfeminism, transparens och audience labour utreder vi den roll emoti

Riitta ojala

Creating Ecological Citizenship An Example of Voluntary Oil-Combating in Finland Thesis Submitted in Fulfilment of the Requirements of LUMES – Lund University Master’s Programme in International Environmental Science At Lund 21st of November 2005 Author: Riitta Ojala Lund University LUMES Alakatu 6 39700 Parkano, Finland E-mail: riitta.ojala.296@student.lu.se Phone: +46 73 65 12 109 Supervisor: An

https://www.lumes.lu.se/sites/lumes.lu.se/files/riitta_ojala.pdf - 2026-05-30

Blood Levels of Dendritic Cell Populations in Patients with Moderate to Severe Traumatic Brain Injury

Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells activated by TBI remains poorly defined. Several animal models showing invasion of circulating classical dendritic cells type 2 (cDC2s) to the traumatically in

Differential effects of overexpression of mutant huntingtin and TDP-43 in agouti-related protein neurons in the arcuate nucleus of the hypothalamus in mice

The spectrum of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS) and Huntington disease (HD) are fatal neurodegenerative disorders with no major disease-modifying therapies. Recent work has shown that the hallmark pathological proteins TAR DNA binding protein of 43 kDa (TDP-43) in FTD/ALS and mutant huntingtin (mHTT) in HD may be interlinked. Furthermore, these disorders share early

Ultra-hypofractionated versus conventionally fractionated radiotherapy for localised prostate cancer (HYPO-RT-PC) : 10-year outcomes of an open-label, randomised, phase 3, non-inferiority trial

BACKGROUND: HYPO-RT-PC is a phase 3 trial comparing ultra-hypofractionated and conventionally fractionated radiotherapy in intermediate-to-high-risk localised prostate cancer. This 10-year update reports long-term efficacy and toxicity outcomes.METHODS: In this open-label, randomised, phase 3, non-inferiority trial done in ten centres in Sweden and two in Denmark, we recruited men aged 75 years or

Impact of the COVID-19 pandemic on emergency and elective hip surgeries in Norway

Background and purpose — Many countries implemented strict lockdown policies to control the COVID-19 pandemic during March 2020. The impacts of lockdown policies on joint surgeries are unknown. Therefore, we assessed the effects of COVID-19 pandemic lockdown restrictions on the number of emergency and elective hip joint surgeries, and explored whether these procedures are more/less affected by loc