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Patient choice and socioeconomic disparities in the quality of healthcare : Evidence from Swedish registry data

This study explores socioeconomic disparities in how patients trade off quality against other features when choosing their primary care provider. We use a unique registry dataset linking the choices of individuals who recently moved to a new market, and therefore need to select a new provider, with detailed individual-level measures of socioeconomic status (SES) and provider-level measures of pati

Exercise Systolic Blood Pressure Response During Cycle Ergometry is Associated with Future Hypertension in Normotensive Individuals

AimsWe aimed to investigate the association between the exercise systolic blood pressure (SBP) response and future hypertension (HTN) in normotensive individuals referred for cycle ergometry, with special regard to reference exercise SBP values and exercise capacity.Methods and resultsIn this longitudinal cohort study, data from 14 428 exercise tests were cross-linked with Swedish national registr

Meaning of home attenuates the relationship between functional limitations and active aging

Background and aims: Active aging is the process through which people strive to maintain wellbeing when growing old. Addressing the lack of research on active aging in the context of housing, the aim was to describe active aging among people aged 55 and older considering relocation and investigate whether perceived housing moderates the relationship between functional limitations and active aging.

Silica seed particles improve the efficiency and throughput of nanoparticle acoustic trapping

Silica has rarely been used as a seed particle material in acoustic trapping of nanoparticles. Here we use fluorescent nanoparticles, which are frequently used as a model system, to demonstrate that throughput and nanoparticle trapping efficiency can be improved by using silica seed particles as opposed to traditionally used polystyrene seed particles. The 10 times larger dipole scattering coeffic

Performance Based Specification of Wood - Project CLICKdesign

This paper introduces the ForestValue research project CLICKdesign - delivering fingertip knowledge to enable service life performance specification of wood. The consortium is working on a primary innovation to move from the complex, fragmented and general to the easy-to-use, consolidated and specific by provision of a digital tool for specifiers. Other materials tackle this and provide designers

The Swedish Environmental Classification and Information System for Pharmaceuticals - An empirical investigation of the motivations, intentions and expectations underlying its development and implementation

In 2005 the Swedish Association of the Pharmaceutical Industry (LIF) initiated a national environmental classification and information system for pharmaceuticals. This investigation reports the results from a survey, conducted among the persons involved in the start-up process. The aim of this study is to generate knowledge contributing to the clarification of the motivations, expectations, and in

Inflammatory bowel disease induces pathological α-synuclein aggregation in the human gut and brain

Aims: According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous system (ENS) and spreads to the brain through the vagus nerve. In this work, we studied whether inflammatory bowel diseases (IBDs) in humans can progress with the emergence of pathogenic α-synuclein (α-syn) in the gastrointestinal tract and midbrain dopaminergic neurons. Methods:

Structuring Concepts of Legal Personhood : On Legal Personhood as a Cluster Property

Legal persons have traditionally been understood as entities with legal rights and/or duties. This traditional concept of legal personhood has been challenged during the last decades: In legal practice through the global development in law where previous legal non-persons such as different non-human natural entities, non-human animals, fetuses and artificial intelligences have been ascribed, or be

The role of extracellular vesicle fusion with target cells in triggering systemic inflammation

Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring bioactive molecules from donor to recipient cells. As a result, EV fusion leads to the modulation of cellular functions and has an impact on both physiological and pathological processes in the recipient cell. This study explores the impact of EV fusion on cellular responses to inflammatory signaling. O

Whole-channel acoustic energy and acoustophoretic efficiency frequency spectrum by the in-flow focusing method

The in-flow focusing method, introduced herein, enables rapid and straightforward measurements of the whole-channel acoustic energy of acoustic flow-through devices. The method is applied to assess the whole-channel acoustic energy and acoustophoretic efficiency frequency spectra of a bottom-actuated silicon-glass and a side-actuated glass chip. The input variables are the time-independent geometr

How to evaluate exertional breathlessness using normative reference equations in research

Purpose of review Breathlessness is a common, distressing and limiting symptom in people with advanced disease, but is challenging to assess as the symptom intensity depends on the level of exertion (symptom stimulus) during the assessment. This review outlines how to use recently developed normative reference equations to evaluate breathlessness responses, accounting for level of exertion, for va

Livsdugliga data i gränslandet mellan vård, styrdokument och teknik

Biblioteks- och informationsvetenskaplig forskning har visat hur infrastruk-turer och data inte är neutrala utan bidrar till att forma både det som de re-presenterar och sammanhangen där de används. Vi utgår från dessa insik-ter och diskuterar i artikeln en nyhetsrapportering från november 2015 som handlade om en eventuell förändring av abortgränsen i Sverige. Registerda-ta från Svenskt Neonatalt Library and information studies research has shown how infrastructures and data are, contrary to common perceptions, not neutral but take part in sha- ping what they represent and the contexts in which they are used. Starting off from these insights we discuss Swedish media reports from November 2015 about a possible alteration of the abortion limit due to recent findings in neonatal care and rese

The cost and burden of cancer in the European Union 1995–2014

Background: There is an intense debate about the cost of cancer and the value of new treatments. However, there is limited data on the cost of cancer in the European Union (EU) and how costs relate to the burden of disease. This paper presents new estimates on the development of the cost of cancer in the EU 1995–2014, with a focus on the major cost components: total health expenditure, cancer drug

Comparator report on patient access to cancer medicines in Europe revisited

In a new report, the Swedish Institute for Health Economics (IHE) compares the cancer situation in EU28 plus Norway and Switzerland. The report builds on a previous comparative study conducted in 2005 and provides a comprehensive view of the development of cancer in Europe over the past two decades. The report shows that the number of people diagnosed with cancer continue to increase in Europe, up