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It is disclosed a circuit for extracorporeal blood treatment in which a flow-inverting device is interposed between a blood treatment unit and a blood pump placed on an artery branch connected with a vascular access of a patient. The flow-inverting device allows the blood flow within the filtering unit to be kept unchanged even following an inverted circulation in the patient-side artery and vein
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Background: GEOMAGIA50.v3 for sediments is a comprehensive online database providing access to published paleomagnetic, rock magnetic, and chronological data obtained from lake and marine sediments deposited over the past 50 ka. Its objective is to catalogue data that will improve our understanding of changes in the geomagnetic field, physical environments, and climate. Findings: GEOMAGIA50.v3 for
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Many migratory birds have changed their timing of arrival at breeding grounds in response to recent climate change. Understanding the adaptive value and the demographic consequences of these shifts are key challenges. To address these questions we extend previous models of phenological adaptation to climate change under territory competition to include feedback from population dynamics, winter sur
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Shrubs have increased in abundance and dominance in arctic and alpine regions in recent decades. This often dramatic change, likely due to climate warming, has the potential to alter both the structure and function of tundra ecosystems. The analysis of shrub growth is improving our understanding of tundra vegetation dynamics and environmental changes. However, dendrochronological methods developed
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Background: Type 2 diabetes and its cardiovascular disease complications are the major public health threats of our century. Although physical activity and dietary changes are the cornerstones in prevention of diabetes, their broad implementation is not elementary and other complementary lifestyle regimens are needed. Summary: Vasopressin (VP) is the main regulator of body water homeostasis, and a
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We propose a signal-to-noise criterion which predicts whether a feature of a given size and scattering strength, placed inside a larger object, can be retrieved with two common X-ray imaging techniques: coherent diffraction imaging and projection microscopy. This criterion, based on how efficiently these techniques detect the scattered photons and validated through simulations, shows in general th
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In every human being, there is a substantial proportion (1-2 kg) of total body weight constituted by the gut microbiota content in the gastro-intestinal system. Recent research findings, based on mapping of the microbiome, have stated that in healthy subjects, the gut microbiota richness and diversity is higher as compared to obese subjects or patients suffering from cardiometabolic disease, or ev
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Mixed cultures of a heterotrophic nitrifier/aerobic denitrifier, Thiosphaera pantotropha, and an autotrophic nitrifier, Nitrosomonas europaea, were grown in chemostats under dual ammonia-and acetate limitation. Because of simultaneous nitrification and denitrification by T. pantotropha, the activity of the cultures was evaluated from nitrogen balances as complete as possible. Under most conditions
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The key steps in cellular signaling and regulatory pathways rely on reversible noncovalent protein-ligand binding, yet the equilibrium parameters for such events remain challenging to characterize and quantify in solution. Here, we demonstrate a microfluidic platform for the detection of protein-ligand interactions with an assay time on the second timescale and without the requirement for immobili
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Object: To present population-based and age related incidence of surgery and clinical outcome for adult patients operated for hydrocephalus, registered in the Swedish Hydrocephalus Quality Registry (SHQR). Methods: All patients registered in SHQR during 2004–2011 were included. Data on age, gender, type of hydrocephalus and type of surgery were extracted as well as three months outcome for patient
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A new detailed kinetic mechanism for formaldehyde and methanol combustion has been developed using the Konnov mechanism, version 0.6, as a starting point. In total, 82 reactions of the formaldehyde and methanol subsets were reviewed and updated using a systematic approach. Rate constants were selected based on thorough evaluation of available experimental and theoretical data. No modifications of
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This paper suggests an infrastructure perspective, as suggested by Star and Bowker (2006), as an analytical framework for studying the research evaluation landscape. An infrastructure is suggested to be understood, not as a concrete technology, but as a system of contextual factors including ‘Actors/Stakeholders’, ‘Technical systems’, and ‘Evaluation practices’. How the framework can be operationa
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There is substantial evidence that preschooler’s performance in early math is highly correlated to math performance throughout school as well as academic skills in general. One way to help children attain early math skills is by using targeted educational software and the paper discusses potential gains of using such software to support early math development. Furthermore it is argued that the con
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Flow injection analysis provides a convenient platform for the use of biosensors in the monitoring of bio-processes. A major requirement in bioprocess monitoring is real time information about various process parameters like concentration of products and substrates, flow rates, and injection volumes. Depending on the application, the monitoring requirements vary and this results in a need for diff
