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Model-based predictions on health benefits and budget impact of implementing empagliflozin in people with type 2 diabetes and established cardiovascular disease

Aim: To perform a model-based analysis of the short- and long-term health benefits and costs of further increased implementation of empagliflozin for people with type 2 diabetes and established cardiovascular disease (eCVD) in Sweden. Materials and Methods: The validated Institute for Health Economics Diabetes Cohort Model (IHE-DCM) was used to estimate health benefits and a 3-year budget impact,

Women’s experience of the decision-making process for home-based postnatal midwifery care when discharged early from hospital : A Swedish interview study

INTRODUCTION Women and their families are often excluded from reproductive decisionmaking processes in postnatal care, and do not know which choices they have. Shared decision-making is a critical but challenging component of maternity care quality. The aim was to explore women's experience of the decision-making process about early return from hospital with home-based postnatal midwifery care. ME

On Control and Estimation of Large and Uncertain Systems

Avhandlingen, som är av sammanläggningstyp och innehåller 6 konferensartiklar, behandlar reglering av storskaliga och system med osäkra modeller. Den första artikeln introducerar ett deterministiskt alternativ till "multiple-model estimation" för ändliga mängder av linjära system. Estimatet är en interpolation av Kalman-filter estimat och har begränsad förstärkning från störningar till punktskattnThis thesis contains an introduction and six papers about the control and estimation of large and uncertain systems. The first paper poses and solves a deterministic version of the multiple-model estimation problem for finite sets of linear systems. The estimate is an interpolation of Kalman filter estimates. It achieves a provided energy gain bound from disturbances to the point-wise estimation e

Real-world costs of continuous insulin pump therapy and multiple daily injections for type 1 diabetes : A population-based and propensity-matched cohort from the Swedish National Diabetes Register

OBJECTIVE To investigate real-world costs of continuous insulin pump therapy compared with multiple daily injection (MDI) therapy for type 1 diabetes. RESEARCH DESIGN AND METHODS Individuals with type 1 diabetes and pump therapy in the Swedish National Diabetes Register (NDR) since 2002 were eligible. Control subjects on MDI were matched 2:1 using time-varying propensity scores. Longitudinal data

Navigating between rules and reality : a qualitative study of HIV positive MSM’s experiences of communication at HIV clinics in Sweden about the rules of conduct and infectiousness

The rules of conduct given to people living with HIV in Sweden in accordance with the Swedish Communicable Diseases Act stipulate disclosure obligation to sexual partners and mandatory condom use. Since 2013, treating physicians have the possibility to exempt patients from this disclosure obligation when no considerable risk of transmission is present. This study explored experiences of communicat

Understanding and Improving Continuous Experimentation : From A/B Testing to Continuous Software Optimization

Kontrollerade experiment (t.ex. A/B test) används av många företag med användarintensiva produkter för att förbättra mjukvara med hjälp av användardata. Några företag anammar ett experimentdrivet tillvägagångssätt för mjukvaruutveckling med kontinuerliga experiment (KE). Med KE så utvärderas alla förändringar som påverkar användare med ett experiment och det finns specialiserade roller som aktivt Controlled experiments (i.e. A/B tests) are used by many companies with user-intensive products to improve their software with user data. Some companies adopt an experiment-driven approach to software development with continuous experimentation (CE). With CE, every user-affecting software change is evaluated in an experiment and specialized roles seek out opportunities to experiment with functiona

Cost analysis of informal care : estimates from a national cross-sectional survey in Sweden

Background: Over the past decades, informal care has increased in most OECD-countries. Informal care is costly to caregivers and to society in the form of lost income and direct costs of providing care. Existing evidence suggests that providing informal care affects caregivers’ overall health. However, estimates of the social costs of informal care based on national data on individuals are current

Swedish primary care physicians’ intentions to use telemedicine : A survey using a new questionnaire – physician attitudes and intentions to use telemedicine (pait)

Background: Research on intentions to use telemedicine in primary care is sparse. This survey study explored primary care physicians’ intentions to use telemedicine by using a newly developed questionnaire: Physician Attitudes and Intentions to use Telemedicine. Methods: An anonymous web-survey with questions focusing on theory-based predictors of behavioral intentions such as Attitudes, Subjectiv

Asthma referrals : A key component of asthma management that needs to be addressed

Heterogeneity of asthma and difficulty in achieving optimal control are the major challenges in the management of asthma. To help attain the best possible clinical outcomes in patients with asthma, several guidelines provide recommendations for patients who will require a referral to a specialist. Such referrals can help in clearing the uncertainty from the initial diagnosis, provide tailored trea

Implementation of Choice From Participants' Perspectives: A Study of Community Mental Healthcare Reform in Sweden.

The aim of this study was to explore participants' experiences and opinions about a free-choice system in relation to policy objectives articulated by the national government and local authorities. A case study was conducted. Thirty five informants participated. Qualitative interviews were undertaken. Results discussed are how to address different dimensions of choice, not only where, also what, b

Romanfigurer ger liv åt tentans patientfall

I Lund avslutas läkarutbildningens tionde termin med en MEQ-skrivning (Modified Essay Questions). Höstterminen 2002 hämtade vi bakgrundsmiljö och persongalleri till frågornas fallbeskrivningar från ett skönlitterärt verk. Initiativet föll väl ut hos studenterna – de tyckte att boken var bra och att upplägget var utmärkt. Också författaren var nöjd – efter vår »medikalisering« lärde han känna sina

Statslöshet i internationell rätt : en begreppshistorisk analys av begreppet statslöshet i dokument från International Law Commission år 1952-54 och UNHCR år 2014-2015

Denna uppsatsen undersöker begreppet statslöshet i en världsstruktur där fokus ligger på att erhållande av nationalitet är essentiellt vid infriande av mänskliga rättigheter. Efter andra världskriget blev många statslösa och därför undersöker jag i denna uppsats begreppet statslöshets innebörd i dokumenten från International Law Commission under 1952-1954. Jag jämför begreppets innebörd från ovans

En ren rätt - Ett arbete om renskötselrätten och dess grunder utifrån Girjasdomen

Denna framställning utgör en rättslig analys av Gällivare tingrätts dom angående Girjas sameby. Denna dom är i skrivande stund inte slutligt avgjord utan har överklagats till hovrätten. Tingsrätten slöt sig till att rennäringslagen stred mot egendomsskyddet i regeringsformen och lämnade denna lag utan avseende. Domstolen dömde till samebyns fördel i målet med stöd av rättsinstitutet urminnes hävd.This essay accounts for a legal analysis of a case that has been ruled by a Swedish district court (Girjasdomen). This case is appealed to a court of appeal, so the matter has not yet become final. The court stated that parts of the reindeer industry law (rennäringslagen) were not applicable in the current case due to the conflict with the property protection (egendomskyddet). The court ruled in f

Responsibility to protect - En analys av skyldigheten att skydda

Humanitära interventioner, alltså militära ingripanden i en stat utan dess samtycke för att skydda befolkningens mänskliga rättigheter, har under de senaste årtiondena varit omdiskuterade. Interventionernas förespråkare menar att vi alla har en moralisk skyldighet att hjälpa människor i nöd. De som är kritiska till interventionerna menar att dessa innebär en kränkning av en av folkrättens hörnstenHumanitarian interventions, that is to say military interventions in a state, without its permission, to protect the population’s human rights, have during the past decades been controversial. The advocates of the interventions regard it as everyone’s duty to help humans in need. The interventions’ critics argue that the interventions are a violation of one cornerstone of the international law, th

Responsibility to Protect and International Law - The Case of the Rohingya

Rohingya-muslimerna i Myanmar har utsatts för diskriminering och förtryck i många decennier. Sedan 2012 har våldet i Myanmar eskalerat till vad många menar är folkmord. De påstådda brotten har fått uppmärksamhet i det internationella samfundet och särskilt inom området internationella mänskliga rättigheter. Examensarbetet gör en kritisk granskning av frågor relaterade till det internationella ansvThe Rohingya, a Muslim minority group in Myanmar have been subject to discrimination and repression for many decades. Since 2012, the violence in Myanmar has escalated to mass atrocity crimes, arguably amounting to genocide. The alleged crimes have gained attention in the international community and especially in the field of international human rights law. This thesis makes a critical examination

KURSI - Furniture for Lodges in Nepal (Mountaineous Region)

This project named Kursi aims to address the design challenges specific to the moun- tainous regions of Nepal. These areas are renowned for trekking and can only be reached after days of arduous hiking or by air travel, typically through helicopters. Tourism plays a significant role in the lives of the local communities, and the landscape has adapted to accommodate these temporary residents who

Factors associated with patients self-reported adherence to prescribed physical activity in routine primary health care

Background: Written prescriptions of physical activity have increased in popularity. Such schemes have mostly been evaluated in terms of efficacy in clinical trials. This study reports on a physical activity prescription referral scheme implemented in routine primary health care (PHC) in Sweden. The aim of this study was to evaluate patients' self-reported adherence to physical activity prescripti